RCI & CAPA Senior Manager

You will lead Root Cause Investigation (RCI) and Corrective and Preventive Action (CAPA) activities across research and development and related functions. You will work closely with quality, safety, clinical and regulatory to resolve complex issues and reduce future risk. We value clear thinkers who listen, influence with empathy, and drive practical, data-led solutions. This role offers visible impact, real career growth and the chance to shape processes that help us unite science, technology and talent to get ahead of disease together.

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme. We embrace modern work practices; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work.

Responsibilities

• Lead end-to-end root cause investigations for cross-functional and high-risk issues, using structured methods to reach evidence-based conclusions.
• Coach and support colleagues on investigation tools, risk assessment and SMART CAPA design.
• Oversee the CAPA closure and effectiveness implementation.
• Partner with process owners and stakeholders to simplify workflows, reduce recurrence and improve issue management practices.
• Facilitate the management review and oversight by proactively monitoring signals and business performance.
• Assess Issues for criticality and Serious Breaches.

Why you?

Basic Qualifications & Skills

• Degree in a life science, engineering, quality, or related field, or equivalent experience.
• Significant experience in issue investigation, CAPA management, quality or risk roles within pharmaceutical, vaccines, or life sciences settings.
• Demonstrated experience leading root cause analyses and implementing CAPAs in a regulated environment.
• Strong knowledge of quality management systems and applicable regulatory expectations.
• Proven ability to influence across a matrix organisation and lead cross-functional teams.
• Comfortable working in a hybrid model, with an expectation to be on-site regularly.

Preferred Qualifications & Skills

• Advanced degree (MSc, PhD or equivalent) in a relevant discipline.
• Formal training or certification in root cause analysis, Six Sigma, Lean or similar methodologies.
• Experience supporting regulatory inspections or preparing for audits.
• Experience of assessing Issues for criticality and Serious Breaches.
• Track record of process improvement and measurable impact through CAPA effectiveness.
• Experience working with digital tools for quality management, analytics or workflow tracking.
• Familiarity with global regulatory frameworks and guidance relevant to clinical and quality activities.

Closing

Closing Date for Applications – 12th of February 2026 (COB)

Please take a copy of the Job Description, as this will not be available post closure of the advert. When applying for this role, please use the “cover letter” of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

About GSK: At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at UKRecruitment.Adjustments@gsk.com where you can also request a call. Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide.