Principal Scientist

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.Discover more about our company wide benefits and life at GSK on our webpage Life at GSK.At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people\’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients\’ needs and have the highest probability of success. We\’re uniting science, technology, and talent to get ahead of disease together.Principal Scientist As a Principal Scientist you will lead scientific work that helps teams make faster, better decisions. You will design, validate and execute experiments that support both early and late clinical studies. You will work closely with project teams, laboratory colleagues and external partners. We value clear thinkers who share knowledge, care about quality, and enjoy mentoring others. This role offers strong opportunities to grow your technical and leadership skills while contributing to GSK\’s mission of uniting science, technology and talent to get ahead of disease together. This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:Design, develop and validate robust spectral flow cytometry biomarker assays to support early and late clinical studies.Deliver, interpret and communicate complex scientific data to project/program teams within agreed timelines whilst managing multiple projects concurrently.Ensure high standards for data quality, record keeping and regulatory compliance in a GCP laboratory setting.Support assay transfers and collaborations with external partners and contract research organisations.Drive improvements in laboratory workflows, automation and data analysis to increase efficiency and reproducibility.Contribute to knowledge sharing across the organisation.Why you? Basic Qualifications & Skills We are looking for professionals with these required skills to achieve our goals:MSc or equivalent practical experience in cell biology, immunology, biomedical science, pharmacology or related discipline with a significant computational component OR strong experience in Industry in a similar field having gained an undergraduate degree in one of the disciplines named above.Proven hands-on experience in flow cytometry.Demonstrable experience in assay development and optimisation of 18+ colour panels.Strong data analysis skills and clear written and verbal communication for scientific audiences.Experience working with human biological samples and understanding of relevant safety and ethical requirements.Ability to manage multiple projects, prioritise tasks and meet deadlines in a collaborative team environment.Preferred Qualifications & Skills Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:PhD in a relevant scientific discipline.Practical experience with specific platforms such as the Cytek Aurora flow cytometer and OMIQ analysis software.Significant and demonstrable experience with computational approaches to high dimensional data analysis.Experience with both laboratory and analytical automation.Experience of assay validation, working within GCP or other regulated environments and familiarity with relevant regulatory expectations.Demonstrated ability to influence cross-functional teams and provide scientific leadership on projects.Please take a copy of the Job Description, as this will not be available post closure of the advert.Closing Date for Applications – 6th February 2026When applying for this role, please use the \’cover letter\’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people\’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients\’ needs and have the highest probability of success. We\’re uniting science, technology, and talent to get ahead of disease together.Find out more:Our approach to R&D.#LI-GSKWhy GSK?Uniting science, technology and talent to get ahead of disease together.GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive.We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.People and patients around the world count on the medicines and vaccines we make, so we\’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at UKRecruitment.Adjustments@gsk.com where you can also request a call.Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the Link where you will find answers to multiple questions we receiveImportant notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK\’s commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK\’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

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