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- Tasks: Lead innovative drug development strategies and collaborate with cross-functional teams.
- Company: Join GSK, a leader in inclusive healthcare and innovation.
- Benefits: Competitive salary, remote work options, and opportunities for professional growth.
- Other info: Dynamic role with strong networking and leadership opportunities in a high-impact team.
- Why this job: Make a real impact in drug development and improve patient access to therapies.
- Qualifications: PhD or MD with experience in clinical pharmacology and drug development.
This job is with GSK, an inclusive employer and a member of myGwork – the largest global platform for the LGBTQ+ business community.
The Department of Clinical Pharmacology Modelling & Simulation Respiratory and Inflammation (CPMS R&I) at GSK is recruiting a director-level Clinical Pharmacologist. This role is based in UK or US, with remote working or placement at other European GSK sites possible for the right candidate.
Job Purpose:
The Director, Clinical Pharmacology sits within the newly established Clinical Pharmacology and Quantitative Medicine (CPQM) organisation, which aims to be a centre of excellence in Model‑Informed Drug Development (MIDD) by integrating clinical pharmacology, digital medicine, translational imaging and mechanistic/systems modelling. You will lead the end‑to‑end application of MIDD across the drug development lifecycle—from first‑in‑human studies through filing and lifecycle management—and provide clinical pharmacology strategy and evidence‑generation input. This is an opportunity to join a highly regarded, high‑impact team with a strong publication track record, reporting directly to the Respiratory, Immunology & Inflammation Research Unit (RIIRU).
Main responsibilities:
- Design & Execute Model Informed and Clinical Pharmacology strategies: Develop and implement robust MIDD & ClinPharm evidence strategies to de-risk and accelerate RIIRU programs. Aim for faster development, optimal dosing and stronger regulatory positioning across respiratory, inflammation, neurodegeneration and emerging areas - and support business development opportunities. Ensure robust ways of working and regulatory ready evidence.
- Draft and review clinical pharmacology regulatory content to support timely approvals and optimal labelling. Maintain up to date knowledge of FDA, EMA, CDE, PMDA and ICH expectations and embed regulatory considerations and best practices into study design and MIDD strategies.
- Build cross‑functional partnerships: Work closely with CPQM peers (digital medicine, translational imaging, MIDD specialists, mechanistic/systems modelling) and cross functional partners (biology, data science, computational biology, clinical, etc.). Maintain strong networks and share best practices in the CPMS community of practice. Build strong network key functions such as AI/ML, biomarkers, biostatistics, clinical operations, data science, computational biology and RWE to embed quantitative approaches into decision making at asset level.
- External engagement & scientific leadership: Raise GSK's profile in MIDD, clinical pharmacology, QSP and AI/ML integration through publications, conference presentations and active participation in scientific and regulatory fora to influence method adoption and regulatory dialogue.
Why you?
Basic Qualifications:
- PhD in life sciences or related discipline, MD, or PharmD, with experience in clinical pharmacology, modelling and simulation in pharmaceutical research and development.
- Significant experience in clinical pharmacology, modelling/simulation and drug development to solve practical problems in the pharmaceutical industry.
- Experience in pharmacometrics and their application to clinical questions in drug development.
Preferred Qualifications:
- Additional experience in respiratory and immunology would be beneficial.
- Demonstrated experience of collaboration in a multi-discipline team, using effective communication and taking personal accountability for timely delivery of results.
- Evidenced experience making sound judgement in complex situations and adapting to changing business needs by prioritising multiple tasks.
- Experience working with senior stakeholders in a cross functional environment.
- Track record of implementation of Model-Informed Drug Discovery and Development (MIDD) approaches to accelerate patient access to novel therapies and to expand therapeutic indications of marketed drugs.
- Drive and learning agility to build knowledge on a drug-disease system, symptom progression, standard of care, and trial design.
Director Clinical Pharmacology employer: Gsk
Contact Detail:
Gsk Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Director Clinical Pharmacology
✨Tip Number 1
Network like a pro! Reach out to professionals in the clinical pharmacology field on LinkedIn or at industry events. Building connections can lead to insider info about job openings and even referrals.
✨Tip Number 2
Prepare for interviews by researching GSK's recent projects and publications. Show them you’re not just another candidate; you’re genuinely interested in their work and how you can contribute to their mission.
✨Tip Number 3
Practice your pitch! Be ready to explain how your experience aligns with the role of Director, Clinical Pharmacology. Highlight your skills in MIDD and collaboration with cross-functional teams to make a strong impression.
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets seen by the right people. Plus, it shows you’re serious about joining the GSK team.
We think you need these skills to ace Director Clinical Pharmacology
Some tips for your application 🫡
Tailor Your CV: Make sure your CV is tailored to the Director, Clinical Pharmacology role. Highlight your experience in clinical pharmacology and modelling, and don’t forget to showcase any relevant achievements that align with GSK's goals.
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you're the perfect fit for this role. Mention your passion for Model-Informed Drug Development and how your background can contribute to GSK’s mission.
Showcase Your Collaboration Skills: GSK values teamwork, so be sure to highlight your experience working in multi-disciplinary teams. Share examples of how you've effectively communicated and collaborated with different stakeholders in your previous roles.
Apply Through Our Website: We encourage you to apply through our website for a smoother application process. It’s the best way to ensure your application gets the attention it deserves, so don’t miss out!
How to prepare for a job interview at Gsk
✨Know Your MIDD Inside Out
Make sure you have a solid understanding of Model-Informed Drug Development (MIDD) and its application in clinical pharmacology. Brush up on recent advancements and case studies, as this will show your passion and expertise during the interview.
✨Showcase Your Collaborative Spirit
GSK values teamwork, so be ready to discuss your experience working in multi-disciplinary teams. Prepare examples that highlight how you've effectively communicated and collaborated with different functions, especially in complex projects.
✨Stay Updated on Regulatory Standards
Familiarise yourself with the latest FDA, EMA, and ICH guidelines relevant to clinical pharmacology. Being able to discuss how these regulations impact study design and MIDD strategies will demonstrate your readiness for the role.
✨Prepare for Scenario-Based Questions
Expect questions that assess your problem-solving skills in real-world scenarios. Think about challenges you've faced in drug development and how you navigated them, particularly in relation to pharmacometrics and regulatory submissions.