Principal Investigator

Principal Investigator

Reading Full-Time 48000 - 72000 £ / year (est.) No home office possible
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At a Glance

  • Tasks: Lead clinical trials, ensuring patient safety and data integrity.
  • Company: Join a fast-growing clinical research site network transforming trial delivery.
  • Benefits: Competitive pay, performance incentives, and centralised operational support.
  • Why this job: Make a real impact in clinical research while collaborating with top investigators.
  • Qualifications: Medical degree and prior clinical research experience required.
  • Other info: Opportunities to expand your research portfolio and shape future trials.

The predicted salary is between 48000 - 72000 £ per year.

Lead Physician – London

Overview

An exciting opportunity is available for a senior medical professional to take a leadership role in the delivery of clinical trials involving various Therapy area\’s. The position is ideal for someone with prior Principal Investigator experience and a strong interest in mental health innovation. You’ll be working across dynamic, multi-disciplinary teams, guiding trials from early phases through to completion, while maintaining the highest standards in clinical care, compliance, and operational delivery.

Role Focus

The successful candidate will be responsible for safeguarding participant wellbeing, ensuring trial integrity, and upholding compliance with all relevant clinical regulations and best practices. In this role, you’ll help shape the future of research in an evolving area of mental health treatment.

Key Duties and Responsibilities

  • Take full responsibility for the medical conduct of clinical studies as the lead investigator
  • Ensure all research activities comply with Good Clinical Practice (GCP) guidelines and regulatory standards
  • Conduct eligibility assessments, safety evaluations, and clinical reviews throughout the study lifecycle
  • Make appropriate clinical decisions regarding patient inclusion, dosing readiness, and follow-up care
  • Supervise the reporting of any adverse or serious adverse events and ensure timely communication with relevant oversight bodies
  • Mentor and support clinical teams involved in research delivery, providing ongoing guidance and medical input
  • Collaborate effectively with operational teams, sponsors, and external research partners
  • Review and sign off on essential clinical documentation, including source notes and trial case report forms
  • Oversee the use, control, and accountability of investigational products and other study-related medications
  • Monitor the collection and quality of structured clinical assessments and psychiatric rating scales
  • Keep up to date with developments in psychedelic research and relevant clinical guidelines

Skills and Experience Required

  • Medical qualification with active professional registration and licence to practise
  • Specialist accreditation or membership (e.g., psychiatry, internal medicine, or similar)
  • Prior experience acting as Principal Investigator on clinical trials
  • Solid understanding of regulatory frameworks including GCP, FDA, EMA, and other global standards
  • Previous involvement in psychiatric or CNS-focused studies preferred
  • Confident in managing clinical risk and making sound medical decisions
  • Proficient in clinical assessments and familiar with tools such as MINI, CAPS-5, or C-SSRS
  • Strong communicator, capable of working with diverse teams and external stakeholders
  • Comfortable with oversight of investigational products and protocol compliance

Principal Investigator employer: Green Life Science

Join a pioneering clinical research site network that prioritises innovation and collaboration, offering Principal Investigators the opportunity to lead impactful trials while benefiting from centralised operational support. With a focus on patient care and scientific excellence, our work culture fosters professional growth and provides access to a diverse range of high-quality studies, making it an ideal environment for those looking to advance their careers in clinical research.
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Contact Detail:

Green Life Science Recruiting Team

StudySmarter Expert Advice 🤫

We think this is how you could land Principal Investigator

✨Tip Number 1

Network like a pro! Reach out to fellow researchers and industry contacts on LinkedIn or at conferences. Building relationships can lead to opportunities that aren’t even advertised yet.

✨Tip Number 2

Showcase your expertise! Create a personal website or an online portfolio highlighting your research experience, publications, and any successful trials you've led. This gives potential employers a clear view of what you bring to the table.

✨Tip Number 3

Prepare for interviews by brushing up on the latest trends in clinical research. Be ready to discuss how you can contribute to patient safety and data integrity, as these are key areas for a Principal Investigator.

✨Tip Number 4

Don’t forget to apply through our website! We’re always looking for passionate PIs to join our innovative network. It’s a great way to get noticed and show your interest in being part of our collaborative community.

We think you need these skills to ace Principal Investigator

Medical Leadership
Clinical Research Experience
GCP Certification
Regulatory Compliance
ICH-GCP Knowledge
FDA Regulations Knowledge
EMA/MHRA Regulations Knowledge
Supervision Skills
Documentation Skills
Reporting Skills
Collaboration Skills
Patient Safety Focus
Data Integrity Management
Operational Excellence

Some tips for your application 🫡

Show Your Passion for Research: When writing your application, let your enthusiasm for clinical research shine through. We want to see how your experience aligns with our mission of transforming trial delivery and expanding patient access.

Highlight Relevant Experience: Make sure to detail your previous roles as a Principal Investigator or Sub-Investigator. We’re looking for specific examples that showcase your leadership skills and compliance with regulations like ICH-GCP and FDA guidelines.

Be Clear and Concise: Keep your application straightforward and to the point. We appreciate clarity, so avoid jargon and ensure your qualifications and experiences are easy to understand. This helps us see your fit for the role quickly!

Apply Through Our Website: Don’t forget to submit your application through our website! It’s the best way for us to receive your details and ensures you’re considered for this exciting opportunity in our growing network.

How to prepare for a job interview at Green Life Science

✨Know Your Stuff

Make sure you brush up on your clinical research knowledge, especially around ICH-GCP and regulatory compliance. Being able to discuss these topics confidently will show that you're not just a qualified candidate but also genuinely passionate about the field.

✨Showcase Your Leadership Skills

As a Principal Investigator, you'll be leading teams and overseeing trials. Prepare examples from your past experiences where you've successfully led a team or managed a project. This will help demonstrate your capability to handle the responsibilities of the role.

✨Understand the Organisation's Vision

Research the clinical research site network and understand their mission and values. Be ready to discuss how your goals align with theirs and how you can contribute to expanding patient access to research. This shows that you're not just looking for any job, but that you're invested in their specific mission.

✨Prepare Questions

Interviews are a two-way street! Prepare thoughtful questions about the organisation's approach to trial delivery and how they support their PIs. This not only shows your interest but also helps you gauge if this is the right fit for you.

Principal Investigator
Green Life Science
Location: Reading
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