Principal Investigator

Principal Investigator

Bristol Full-Time 48000 - 72000 £ / year (est.) No home office possible
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At a Glance

  • Tasks: Lead clinical trials, ensuring patient safety and data integrity.
  • Company: Innovative clinical research site network transforming trial delivery.
  • Benefits: Competitive pay, performance incentives, and centralised operational support.
  • Why this job: Shape the future of clinical trials while collaborating with top investigators.
  • Qualifications: Medical degree and prior clinical research experience required.
  • Other info: Join a growing network with opportunities to expand your research portfolio.

The predicted salary is between 48000 - 72000 £ per year.

Lead Physician – London

Overview

An exciting opportunity is available for a senior medical professional to take a leadership role in the delivery of clinical trials involving various Therapy area\’s. The position is ideal for someone with prior Principal Investigator experience and a strong interest in mental health innovation. You’ll be working across dynamic, multi-disciplinary teams, guiding trials from early phases through to completion, while maintaining the highest standards in clinical care, compliance, and operational delivery.

Role Focus

The successful candidate will be responsible for safeguarding participant wellbeing, ensuring trial integrity, and upholding compliance with all relevant clinical regulations and best practices. In this role, you’ll help shape the future of research in an evolving area of mental health treatment.

Key Duties and Responsibilities

  • Take full responsibility for the medical conduct of clinical studies as the lead investigator
  • Ensure all research activities comply with Good Clinical Practice (GCP) guidelines and regulatory standards
  • Conduct eligibility assessments, safety evaluations, and clinical reviews throughout the study lifecycle
  • Make appropriate clinical decisions regarding patient inclusion, dosing readiness, and follow-up care
  • Supervise the reporting of any adverse or serious adverse events and ensure timely communication with relevant oversight bodies
  • Mentor and support clinical teams involved in research delivery, providing ongoing guidance and medical input
  • Collaborate effectively with operational teams, sponsors, and external research partners
  • Review and sign off on essential clinical documentation, including source notes and trial case report forms
  • Oversee the use, control, and accountability of investigational products and other study-related medications
  • Monitor the collection and quality of structured clinical assessments and psychiatric rating scales
  • Keep up to date with developments in psychedelic research and relevant clinical guidelines

Skills and Experience Required

  • Medical qualification with active professional registration and licence to practise
  • Specialist accreditation or membership (e.g., psychiatry, internal medicine, or similar)
  • Prior experience acting as Principal Investigator on clinical trials
  • Solid understanding of regulatory frameworks including GCP, FDA, EMA, and other global standards
  • Previous involvement in psychiatric or CNS-focused studies preferred
  • Confident in managing clinical risk and making sound medical decisions
  • Proficient in clinical assessments and familiar with tools such as MINI, CAPS-5, or C-SSRS
  • Strong communicator, capable of working with diverse teams and external stakeholders
  • Comfortable with oversight of investigational products and protocol compliance

Principal Investigator employer: Green Life Science

Join our innovative clinical research site network, where we prioritise patient care and scientific excellence. With a strong focus on collaboration and operational support, we offer Principal Investigators the opportunity to lead diverse studies while enjoying competitive compensation and performance incentives. Our commitment to employee growth and a supportive work culture makes us an exceptional employer in the clinical research field.
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Contact Detail:

Green Life Science Recruiting Team

StudySmarter Expert Advice 🤫

We think this is how you could land Principal Investigator

✨Tip Number 1

Network like a pro! Reach out to fellow researchers and industry professionals on LinkedIn or at conferences. Building connections can lead to opportunities that aren’t even advertised yet.

✨Tip Number 2

Showcase your expertise! Create a personal website or an online portfolio highlighting your research experience, publications, and any relevant projects. This gives potential employers a quick glimpse of what you bring to the table.

✨Tip Number 3

Prepare for interviews by brushing up on common questions and scenarios specific to clinical trials. We recommend practising with a friend or mentor to build confidence and refine your responses.

✨Tip Number 4

Don’t forget to apply through our website! It’s the best way to ensure your application gets noticed. Plus, we love seeing candidates who are proactive about their job search.

We think you need these skills to ace Principal Investigator

Medical Leadership
Clinical Research Experience
GCP Certification
Regulatory Compliance
ICH-GCP Knowledge
FDA Regulations Knowledge
EMA/MHRA Regulations Knowledge
Supervision Skills
Documentation Skills
Reporting Skills
Operational Excellence
Collaboration Skills
Patient Safety Focus
Data Integrity Management

Some tips for your application 🫡

Tailor Your CV: Make sure your CV is tailored to highlight your experience as a Principal Investigator. Focus on your clinical research background, leadership skills, and any relevant certifications. We want to see how your unique experiences align with our mission!

Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you’re passionate about clinical research and how you can contribute to our innovative network. Keep it engaging and personal – we love to see your personality come through!

Showcase Your Compliance Knowledge: Since compliance is key in our field, make sure to highlight your understanding of ICH-GCP, FDA, and EMA/MHRA regulations in your application. We’re looking for candidates who can ensure patient safety and data integrity right from the start.

Apply Through Our Website: We encourage you to apply directly through our website for a smoother process. It’s the best way for us to receive your application and get you into our system quickly. Plus, you’ll find all the details you need about the role there!

How to prepare for a job interview at Green Life Science

✨Know Your Stuff

Make sure you brush up on your clinical research knowledge, especially around ICH-GCP and regulatory compliance. Being able to discuss these topics confidently will show that you're not just a candidate, but a knowledgeable leader ready to take charge.

✨Showcase Your Leadership Skills

As a Principal Investigator, you'll be leading teams and ensuring patient safety. Prepare examples from your past experiences where you've successfully led a team or managed a trial. This will help demonstrate your capability to oversee operations effectively.

✨Understand the Organisation's Vision

Familiarise yourself with the organisation's mission and values. Be ready to discuss how your goals align with theirs, particularly in expanding patient access to research. This shows that you're not just looking for a job, but are genuinely interested in contributing to their vision.

✨Prepare Questions

Interviews are a two-way street! Prepare insightful questions about the clinical trials they conduct and the support systems in place. This not only shows your interest but also helps you gauge if this is the right fit for you.

Principal Investigator
Green Life Science
Location: Bristol
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