Senior Principal Engineer - Graph in Ware

The primary purpose of this role is to take technical accountability for the CMC Knowledge Graph, driving forward its design and implementation through being hands-on and by providing technical direction and oversight to the rest of the development team, while also working closely with Product Management, business representatives and other Tech & Data experts to ensure that it meets the business requirements.

More broadly, the role will additionally:

• Support the CMC Knowledge System Director, product managers, business leaders and other stakeholders to identify opportunities where Knowledge Graph and other Data & AI capabilities can have a transformative impact on GSK’s CMC and New Product Introduction (NPI) processes.
• Provide technical leadership for other Data & AI Products in the CMC/NPI portfolio.

The immediate priority in the role is to drive the technical work needed to productionise an existing proof-of-concept CMC Knowledge Graph and its associated analytics use-cases into a full-fledged, sustainable, supportable Data & AI Product.

In this role you will…

• Lead the ongoing technical design, development, testing and release of the CMC Knowledge Graph and other Data & AI solutions in CMC/NPI portfolio.
• Provide leadership, technical guidance, and mentorship to the development team (both internal staff and contractors), driving performance and continuous improvement, including identifying and realising opportunities to increase velocity.
• Use hands-on technical problem-solving expertise to address technical challenges throughout the product life-cycle.
• Support Product Management in creating and evolving a compelling Product vision and roadmap, using expertise and insights on the art-of-the-possible as well as in engaging users and other business stakeholders to gather feedback and identify system enhancements.
• Collaborate with Data & AI Architecture team and other stakeholders to ensure alignment with established architecture standards, contributing to and evolving them to incorporate new technologies and patterns as needed.
• Ensure compliance with relevant policies and procedures (including GxP validation where required).
• Provide input to, reviewing and approving key technical documents (e.g. design spec, validation plan).
• Stay updated with the latest advancements in Knowledge Graph and related technologies, recommending and implementing improvements to enhance system functionality and performance.
• Lead discovery / proof-of-concept activities to establish early technical feasibility of new Products or Product Features.

Basic Qualifications/Experience:

We are looking for professionals with these required skills to achieve our goals:

• Strong technical expertise in designing, developing, and supporting Knowledge Graphs, including proficiency in working with RDF graph technologies, preferably Azno.
• Proven track record in delivering complex data engineering projects in a cloud environment, preferably Azure.
• Experience in leading and managing technical teams.
• Expertise in data modelling/ontologies, data integration, and data transformation techniques.
• Strong programming skills and proficiency in utilising code repositories, such as Git, for efficient version control, collaboration, and code management.
• Experience with DevOps principles and CI/CD practices to automate software delivery, streamline development processes, and ensure efficient deployment and monitoring.

Preferred Qualifications/Experience:

If you have the following characteristics, it would be a plus:

• Understanding of pharmaceutical industry data and domain knowledge within CMC.
• Knowledge of GxP compliance requirements and experience implementing them in data engineering projects.

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organization where people can thrive.

Getting ahead means preventing disease as well as treating it, and we aim to positively impact the health of 2.5 billion people by the end of 2030.

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy.

We’re committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.

As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

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