Principal Scientist, Innovation ETCT in Stevenage

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme. We embrace modern work practices; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work.

The Extracellular Targeted Cancer Therapeutics (ETCT) Biology Unit within the Oncology Research Unit is seeking an experienced Principal Scientist to contribute to internal initiatives designed to accelerate the build of a targeted biologics portfolio in Oncology. The candidate will collaborate with an experienced team of scientists in using bioinformatic data for target ID/validation and interface with key internal/external business partners to accelerate next generation biologics asset development. The successful applicant will have prior experience managing cross-functional biologics matrix teams with oversight of critical path biology in the preclinical development of novel biologics for cancer therapy.

In this role you will:

• Lead target discovery screening and early biologics programs, specifically antibody drug conjugates (ADCs) and T cell engaging bispecific antibodies (TCEs).
• Collaborate with internal platform groups to deliver success on externally partnered programs and/or technologies.
• Contribute to analyses of external technology to build next generation ADCs and TCEs.

Basic Qualifications & Skills:

We are looking for professionals with these required skills to achieve our goals:

• PhD or equivalent experience in Cancer Biology, Pharmacology, Cellular Biology, or related life science fields.
• Experience in progressing cancer therapies from target ID to candidate selection and supporting critical path mechanistic biology and/or in vivo translational studies.
• Experience executing target discovery/validation and experimental medicine development of biologics assets for cancer therapy.
• Experience leading cross-functional drug discovery project teams.
• Scientific experience leading hybrid internal/external collaboration teams.

Preferred Qualifications & Skills:

Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:

• Pharmaceutical or biotechnology industry research and leadership experience in preclinical oncology biologics drug discovery.
• Strong organizational and interpersonal skills and the ability to work independently.
• Excellent communication and collaboration skills, with a proven track record of working effectively in a multidisciplinary environment.

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.