At a Glance
- Tasks: Lead the reliability and performance of a cutting-edge data platform in genomics.
- Company: Join a pioneering TechBio company transforming healthcare with genomics.
- Benefits: Competitive salary, flexible working, generous leave, and comprehensive health benefits.
- Other info: Dynamic, inclusive culture with clear career progression and continuous learning opportunities.
- Why this job: Make a real impact on healthcare by shaping innovative data solutions.
- Qualifications: Expertise in large-scale OLAP systems and reliability engineering for data platforms.
The predicted salary is between 81000 - 99000 £ per year.
Location: Oxford or London (Hybrid)
The Mission: Why We Exist
Genomics is a science-led transatlantic TechBio combining large-scale genetic and health data with proprietary analytics to accelerate drug discovery and advance predictive, preventative healthcare. We are united by a single vision to help people live longer healthier lives, using the power of genomics.
Role Purpose
Genomics runs on multi-trillion-row, petabyte-scale genetic and health data. Mystra is the analytical data platform that makes that usable, and MystraAI is the agentic layer we are building on top of it. This is a Staff-level role that owns the reliability, performance, security and integrity of that infrastructure end-to-end — and sets the technical direction that other teams build on.
You will lead the analytical data platform and our Data-as-a-Service offering, shape the data foundations behind MystraAI, and line-manage a small team of engineers while staying deeply hands-on.
A Day in the Life
The role spans the full depth of the platform — from low-level infrastructure reliability and database internals up to the systems that serve data across the product. On any given day you might be:
- Architecting, tuning and operating multi-tenant ClickHouse or equivalent OLAP database clusters at multi-trillion-row, petabyte scale.
- Owning SLOs, observability, capacity planning and incident response for data-intensive systems and pipelines.
- Shaping Data-as-a-Service as a real product — a secure, multi-tenant, immutable release architecture.
- Powering agentic AI from the data platform — scaling the data foundations behind MystraAI.
- Treating security as a first-class architectural concern.
- Setting technical direction, mentoring and line-managing a small team of IC2/IC3 engineers.
Who You Are
You are a recognised specialist who leads through expertise — principal-level individual-contributor depth combined with the judgement to set standards others follow. You will bring:
- Large-scale OLAP / ClickHouse experience.
- Reliability engineering for data platforms.
- Data-as-a-Service productisation.
- Agent-ready data understanding.
- Multi-tenant security design.
- Technical leadership skills.
Your Package
We are committed to providing a transparent, supportive, and rewarding work environment.
- Competitive Salary: Salaries are externally benchmarked annually.
- Clear Career Path: A straightforward progression framework.
- Continuous Learning: Including external courses and a wide library of L&D materials.
- Holiday: 25 days annual leave, plus bank holidays, plus an extra 3-day company-wide shutdown at year-end.
- Financial & Health Security: Robust benefits including a market-leading pension scheme and comprehensive private health insurance.
- Enhanced Leave: Enhanced paid family leave to support all new parents.
- Flexible Working: Hybrid Working.
- Truly Inclusive Time Off: Our 'Bank Your Bank Holiday' program.
- Vibrant Social Culture: Regular Town Halls and team events.
- Green Commute: Cycle-to-Work scheme.
Ready to Build the Future? If this opportunity excites you, apply now! We are dedicated to creating a diverse environment and are proud to be an equal-opportunity employer.
Staff Site Reliability Engineer employer: Genomics
Genomics is an exceptional employer that fosters a collaborative and innovative work culture, ideal for those passionate about healthcare technology. With a hybrid work model, employees enjoy flexibility while being part of a team dedicated to impactful product delivery in regulated environments. The company prioritises professional growth, offering numerous opportunities for advancement and skill development in a rapidly evolving field.
