At a Glance
- Tasks: Lead the reliability and performance of a cutting-edge data platform in genomics.
- Company: Join a pioneering TechBio company transforming healthcare with genomics.
- Benefits: Competitive salary, flexible working, generous leave, and continuous learning opportunities.
- Other info: Dynamic, inclusive culture with excellent career growth and vibrant social events.
- Why this job: Make a real impact on healthcare by shaping innovative data solutions.
- Qualifications: Expertise in large-scale OLAP systems and reliability engineering for data platforms.
The predicted salary is between 81000 - 99000 £ per year.
Location: Oxford or London (Hybrid)
The Mission: Why We Exist
Genomics is a science-led transatlantic TechBio combining large-scale genetic and health data with proprietary analytics to accelerate drug discovery and advance predictive, preventative healthcare. We are united by a single vision to help people live longer healthier lives, using the power of genomics.
Role Purpose
Genomics runs on multi-trillion-row, petabyte-scale genetic and health data. Mystra is the analytical data platform that makes that usable, and MystraAI is the agentic layer we are building on top of it. This is a Staff-level role that owns the reliability, performance, security and integrity of that infrastructure end-to-end — and sets the technical direction that other teams build on.
You will lead the analytical data platform and our Data-as-a-Service offering, shape the data foundations behind MystraAI, and line-manage a small team of engineers while staying deeply hands-on.
A Day in the Life
The role spans the full depth of the platform — from low-level infrastructure reliability and database internals up to the systems that serve data across the product. On any given day you might be:
- Architecting, tuning and operating multi-tenant ClickHouse or equivalent OLAP database clusters at multi-trillion-row, petabyte scale.
- Owning SLOs, observability, capacity planning and incident response for data-intensive systems and pipelines.
- Shaping Data-as-a-Service as a real product — a secure, multi-tenant, immutable release architecture.
- Powering agentic AI from the data platform — scaling the data foundations behind MystraAI.
- Treating security as a first-class architectural concern.
- Setting technical direction, mentoring and line-managing a small team of engineers.
Who You Are
You are a recognised specialist who leads through expertise — principal-level individual-contributor depth combined with the judgement to set standards others follow. You will bring:
- Large-scale OLAP / ClickHouse experience.
- Reliability engineering for data platforms.
- Data-as-a-Service productisation.
- Agent-ready data understanding.
- Multi-tenant security design.
- Technical leadership skills.
Your Package
We are committed to providing a transparent, supportive, and rewarding work environment.
- Competitive Salary: Salaries are externally benchmarked annually.
- Clear Career Path: A straightforward progression framework.
- Continuous Learning: Including external courses and a wide library of L&D materials.
- Holiday: 25 days annual leave, plus bank holidays, plus an extra 3-day company-wide shutdown at year-end.
- Financial & Health Security: Robust benefits including a market-leading pension scheme and comprehensive private health insurance.
- Enhanced Leave: Enhanced paid family leave to support all new parents.
- Flexible Working: Hybrid Working.
- Truly Inclusive Time Off: Our 'Bank Your Bank Holiday' program.
- Vibrant Social Culture: Regular Town Halls and team events.
- Green Commute: Cycle-to-Work scheme.
Ready to Build the Future? If this opportunity excites you, apply now! We are dedicated to creating a diverse environment and are proud to be an equal-opportunity employer.
Staff Site Reliability Engineer in Oxford employer: Genomics
Genomics is an exceptional employer that fosters a collaborative and innovative work culture, ideal for those passionate about healthcare technology. With a hybrid work model, employees enjoy flexibility while being part of a team dedicated to impactful product delivery in regulated environments. The company prioritises professional growth, offering numerous opportunities for advancement and skill development in a rapidly evolving field.
StudySmarter Expert Advice🤫
We think this is how you could land Staff Site Reliability Engineer in Oxford
✨Join Local Tech Meetups
Get out there and mingle with fellow developers by joining local tech meetups. It’s a fantastic way to meet people who might be working at Genomics or know someone who does. Plus, you can pick up some trendy tech skills and trends while you're at it!
✨Contribute to Open Source Projects
Show off your coding chops by jumping into open-source projects. Not only does this give you practical experience, but it also gets you noticed in the dev community. You'll create a killer portfolio that speaks volumes about your skills to Genomics.
✨Tap into Online Developer Communities
Don’t underestimate the power of online developer communities like GitHub, Stack Overflow, and even Reddit. Participate in discussions, share your projects, and build your visibility. We can often find opportunities through these channels that can lead to a full-time gig at companies like Genomics.
✨Explore Job Boards Specifically for Tech Roles
Keep your eyes peeled on job boards that focus on tech roles. Sites like TechCareers or Stack Overflow Jobs can often have listings for companies like Genomics that might not show up on broader job sites. Make it a habit to check these regularly, and don’t hesitate to apply directly through our website!
We think you need these skills to ace Staff Site Reliability Engineer in Oxford
Some tips for your application 🫡
Show off your coding skills:When applying for a software engineering role, it's super important to showcase your coding skills. Make sure your CV includes your tech stack, any relevant programming languages you’re comfortable with, and examples of projects you've worked on. If you have a GitHub profile, link it up! We love to see code in action.
Tailor your portfolio:For a full-time role, we’d expect to see some solid examples of your work in your portfolio. Make sure to include at least two or three projects that highlight your problem-solving skills and your ability to work with different technologies. Focus on the projects that are most relevant to the position at Genomics.
Craft a killer cover letter:Your cover letter is your chance to stand out—make it personal! Explain why you want to work at Genomics and how your skills align with the role. Show us your passion for software development. We dig enthusiastic candidates who understand the value of collaboration and continuous learning!
Be clear and concise:When it comes to writing your CV and cover letter, clarity is key. Avoid jargon that could confuse us and stick to simple, direct language. Highlight your achievements with quantifiable results where possible, and keep everything easy to read. A well-organised application goes a long way!
How to prepare for a job interview at Genomics
✨Brush Up on Your Coding Skills
For a full-time software engineering role, it's crucial that we stay sharp with our coding abilities. Expect technical questions that might involve solving problems on the spot or discussing algorithms. Practise on platforms like LeetCode or HackerRank to get comfortable with the types of questions that often come up.
✨Know Your Tools and Frameworks
Make sure we’re well-acquainted with the tools and technologies listed in the job description. Familiarise ourselves with any specific frameworks or programming languages mentioned. If Genomics uses React or Node.js, for instance, be ready to discuss how we’ve used them in previous projects or coursework.
✨Showcase Your Projects
Bring along a portfolio that highlights our best work. This could be code samples, GitHub repositories, or any side projects we’ve built. Make sure we can talk through our thought process for each project, especially the challenges we faced and how we solved them—this shows our problem-solving skills in action.
✨Prepare for Behavioural Questions
While technical skills are key, full-time positions also require cultural fit. Be ready to discuss our previous experiences and how we handle teamwork, conflict, and deadlines. Brush up on the STAR method—Situation, Task, Action, Result—to clearly articulate our past experiences when discussing how we've contributed to a team.
