Senior Product Manager - (Genomic Knowledge Management Products) - 12 Month FTC (we have office[...]

Genomics England is a global leader in enabling genomic medicine and research, focused on creating a world where everyone benefits from genomic healthcare. Building on the 100,000 Genomes Project, we support the NHS’s world‑first national whole genome sequencing service and run the growing National Genomic Research Library, alongside delivering numerous major genomics initiatives. By connecting research and clinical care at national scale, we enable immediate healthcare benefits and advances for the future. Our mission is to provide the evidence and digital systems so that by 2035 genomics could play a role in up to half of all healthcare interactions, whilst securing the UK’s position as the best place to discover, prove and benefit from genomic innovations.

We are hiring a Senior Product Manager to join our Genomic Knowledge Management at Genomics England on a 12‑month fixed‑term contract. This is a high‑impact role leading complex, data‑rich products that make genomic knowledge accurate, trusted and usable across healthcare and research. You will shape products and platforms spanning genomic annotation, reference data, gene‑disease evidence and other genomic knowledge systems that underpin accredited Software as a Medical Device (SaMD) clinical pipelines, research and decision‑making at national scale.

The role is not only about leading today’s products. You will also help shape the future of genomic knowledge capabilities, including the evolution of variant annotation, how emerging technologies and external capabilities could change our approach, and where Genomics England should build, buy, partner or reuse existing solutions. This role sits at the intersection of product, AI, engineering, data, genomics and healthcare. You will work with highly specialised experts to navigate complex dependencies, evolving evidence, technical change and regulatory constraints — bringing clarity to ambiguous problems and making well‑judged product decisions without needing to be the deepest domain expert in the room.

The successful candidate will combine strong product judgement with the ability to build trusted relationships, align different perspectives and lead through influence. You will be comfortable balancing immediate service needs with longer‑term product strategy, and making clear decisions across competing priorities, dependencies and risks.

Everyday responsibilities include:

• Lead the product strategy, roadmap, and outcomes for products within the Knowledge Management squad, ensuring they are aligned to service priorities and organisational OKRs.
• Own and prioritise a complex product backlog, balancing new development, maintenance, technical improvement, compliance, and stakeholder needs.
• Assess build, buy, partner and reuse options, bringing together user value, strategic fit, technical feasibility, cost, risk and long‑term sustainability.
• Work closely with engineers, technical leads, scientists, curators, clinical safety colleagues, service owners, and other product managers to frame problems, evaluate trade‑offs, and make confident decisions.
• Guide the squad through significant technical and data changes, including updates to clinical data, genomic annotation, reference data, and other knowledge assets that affect multiple services and products.
• Collaborate across squads and teams to align roadmaps, manage dependencies, and bring people with you through change, even where you do not have direct authority.
• Use evidence, user insight, operational data, and technical understanding to shape priorities and measure whether the squad is delivering value.
• Ensure products are reliable, well‑supported, and compliant with relevant regulatory, clinical safety, data, quality, and technical standards.
• Communicate clearly with stakeholders at different levels, providing transparency on priorities, risks, decisions, and progress.
• Create space for strategy and discovery while supporting a self‑organising squad to deliver high‑quality outcomes at pace.
• Contribute to a collaborative, inclusive, and continuously improving product community at Genomics England.

Skills and experience for success:

• Strong product management experience, with a track record of leading complex technical, data, scientific or platform products.
• Evidence of strong product leadership, including shaping strategy, roadmaps, priorities and measurable outcomes.
• Ability to make clear, well‑judged product decisions in ambiguous environments, balancing user needs, technical complexity, risk, regulatory considerations and organisational goals.
• Confidence working with highly specialised experts across technical, scientific, clinical or engineering domains, without needing to be the deepest domain expert in the room.
• Excellent stakeholder leadership, with the ability to influence senior leaders, align different perspectives and bring multidisciplinary teams together around shared outcomes.
• Ability to understand complex product ecosystems and make sound product decisions across dependencies between platforms, data products, APIs, services and downstream consumers.

Desirable skills:

• Genomics experience is valuable, but not essential. Product leadership is.
• We are keen to hear from people who have led complex products in specialist domains, whether that is bioinformatics, data platforms, AI/ML, scientific software or healthcare technology.

Qualifications: While your qualifications are certainly important, we are particularly interested in understanding the breadth and depth of your overall experience.

Additional Information:

• Salary from: £86,000
• Closing date for applications: Thursday 16th July

Benefits:

• Generous Leave: 30 days’ holiday plus bank holidays, additional leave for long service, and the option to apply for up to 30 days of remote working abroad annually (approval required).
• Family‑Friendly: Blended working arrangements, flexible working, enhanced maternity, paternity and shared parental leave benefits.
• Pension & Financial: Defined contribution pension (Genomics England double‑matches up to 10%, however you can contribute more if you wish), Life Assurance (3x salary), an Electric Vehicle salary sacrifice scheme and a Give As You Earn scheme.
• Learning & Development: Individual learning budgets, support for training and certifications, and reimbursement for one annual professional subscription (approval required).
• Recognition & Rewards: Employee recognition programme and referral scheme.
• Health & Wellbeing: Subsidised gym membership, a free Headspace account, and access to an Employee Assistance Programme, eye tests, flu jabs.

Equal opportunities and our commitment to a diverse and inclusive workplace:

Genomics England is actively committed to providing and supporting an inclusive environment that promotes equity, diversity and inclusion best practice both within our community and in any other area where we have influence. We are proud of our diverse community where everyone can come to work and feel welcomed and treated with respect regardless of any disability, ethnicity, gender, gender identity, religion, sexual orientation, or social background. Genomics England’s policies of non‑discrimination and equity will be applied fairly to all people, regardless of age, disability, gender identity or reassignment, marital or civil partnership status, being pregnant or recently becoming a parent, race, religion or beliefs, sex or sexual orientation, length of service, whether full or part‑time or employed under a permanent or a fixed‑term contract or any other relevant factor. Genomics England does not tolerate any form of discrimination, harassment, victimisation or bullying at work. Such behaviour undermines our mission and core values and diminishes the dignity, respect and integrity of all parties. Our People policies outline our commitment to inclusivity. We aim to remove barriers in our recruitment processes and to be flexible with our interview processes. Should you require any adjustments that may help you to fully participate in the recruitment process, we encourage you to discuss this with us.

Culture:

We have four key behaviours that represent what we would like Genomics England to feel like and the culture we want to encourage, in order for us to achieve our mission. These behaviours help us all work well together, deliver on our outcomes, celebrate our successes and share feedback with each other.

Blended working model:

Genomics England operates a blended working model as we know our people appreciate the flexibility that hybrid working can bring. We expect most people to come into the office a minimum of 2 times each month. However, this will vary according to role and will be agreed with your team leader. There is no expectation that people will return to the office full time unless they want to, however, some of our roles require full time on site attendance e.g., lab teams, reception team. Our teams and squads have, and will continue to reflect on what works best for them to work together successfully and have the freedom to design working patterns to suit, beyond the minimum. Our office locations are: Canary Wharf, Cambridge and Leeds.

Onboarding background checks:

As part of our recruitment process, all successful candidates are subject to a Standard Disclosure and Barring Service (DBS) check. We therefore require applicants to disclose any previous offences at point of application, as some unspent convictions may mean we are unable to proceed with your application due to the nature of our work in healthcare.