GCP Compliance Manager - Clinical Programs & Trials

For Hybrid working, there is an expectation of 12 days per month onsite. This role can also be provided on a Remote working basis, subject to eligibility criteria. Eligibility for remote work can be discussed at interview stage.

Location: Westworks, London, UK. Other Locations: Dublin, Ireland. This role is based in London, UK. Novartis is unable to sponsor Visas for this location.

Step into a role where your expertise helps Clinical Trial Teams navigate some of their most complex and high‑risk decisions. As a GCP Compliance Manager – Clinical Programs & Trials, you will operate as a trusted partner embedded within the clinical trial environment, working across a portfolio of studies to provide expert guidance on Good Clinical Practice and support teams staying in compliance.

Key Responsibilities

• Provide compliance oversight for clinical programs and trials, ensuring adherence to Good Clinical Practice standards.
• Act as primary compliance partner to Clinical Trial Teams, enabling decision‑making on complex regulatory scenarios.
• Lead cross‑functional discussions and resolution of quality issues using structured investigation and root cause analysis.
• Translate complex regulatory requirements into clear, actionable guidance for cross‑functional clinical stakeholders.
• Coordinate inspection readiness activities, including preparation and inspection management, in addition to subsequent CAPA management.
• Monitor key indicators and trends to detect early signals and support proactive mitigation strategies.
• Deliver self‑assessment checks and controls, sharing insights to strengthen compliance and continuous improvement.
• Collaborate across functions, including Quality Assurance and Development, to ensure aligned and effective compliance practices.
• Support quality assessments of programs and trials and enable informed, risk‑based decision‑making.
• Champion a strong culture of quality, data integrity, and accountability across Global Clinical Operations and beyond.

Essential Requirements

• Advanced degree in science, engineering, or related discipline.
• Significant experience in clinical operations and clinical trial management within a pharmaceutical or healthcare environment.
• Strong knowledge of Good Clinical Practice standards and global regulatory requirements.
• Proven ability to investigate complex issues, perform root cause analysis, and develop effective corrective actions.
• Excellent communication skills with ability to translate technical compliance concepts into clear, practical guidance.
• Strong problem‑solving mindset with curiosity and ability to navigate ambiguity and regulatory trade‑offs.
• Demonstrated ability to work effectively in cross‑functional, matrixed teams and influence diverse stakeholders.
• Ability to work independently, manage multiple trials simultaneously, and prioritise across competing demands.

Desirable Requirements

• Experience supporting audits and inspections, including preparation and interaction with health authority inspections.
• Openness to adopting and experimenting with artificial intelligence and new technologies to optimize ways of working.

Benefits & Rewards

At Novartis, we’re committed to reimagining medicine together - and rewarding the people who make it happen. The base salary offered is determined based on gender-neutral objectives, such as relevant skills, competencies and experience in accordance with the Novartis pay setting policy and upon joining Novartis will be reviewed periodically. In addition to your base salary, you may be eligible for a performance-based bonus depending on certain performance parameters. The rewards of being part of our team go far beyond base pay and incentives. We also offer a variety of competitive benefits in kind to help you thrive personally and professionally, such as insurance plans, retirement plans, wellbeing resources and global recognition programs. In addition, we provide flexible and hybrid working options, where possible, and minimum 14 weeks paid parental leave.

Pay equity is a fundamental principle of our employment policy and reflects our commitment to create a diverse, equitable and inclusive environment that treats all employees with dignity and respect, as outlined in our Code of Ethics.

Novartis is committed to building an outstanding, inclusive work environment and diverse teams’ representative of the patients and communities we serve.

Improving the lives of people living with disease takes more than innovative science. It takes a focus on the needs of people and a community committed to meeting them. It takes a team of people like you. Working together. Learning together. Thriving together. Discover how you can join us in changing people’s lives.