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- Tasks: Lead groundbreaking research in genome editing and stem cell biology.
- Company: Join the Francis Crick Institute, Europe's largest biomedical research hub.
- Benefits: Enjoy generous leave, health support, and career development opportunities.
- Why this job: Make a real impact on human health through innovative scientific research.
- Qualifications: MSc or PhD in relevant field with hands-on stem cell experience.
- Other info: Collaborative environment fostering creativity and diversity.
The predicted salary is between 45700 - 64180 ÂŁ per year.
This is a full‑time permanent position on Crick terms and conditions of employment.
Salary for this Role: From ÂŁ45,700 with benefits, subject to skills and experience.
About us
The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world‑class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state‑of‑the‑art infrastructure, cutting‑edge facilities, and a creative and curious culture. We’ve removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high‑quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy.
About the Stem Cells and Organoid Platform (SCOP)
The Stem Cells and Organoid Platform (SCOP) at the Francis Crick Institute provides expert support to enable research involving human materials and data, while building institutional capability in key areas such as stem cell biology, genetic modification, and human model systems.
About the role
We are seeking a Senior Laboratory Research Scientist (SLRS) to lead gene editing and stem cell research with SCOP. You will drive innovative genome engineering strategies across research and service projects, working at the cutting edge of human model systems. Partnering closely with GeMS and other STPS, you will take scientific ownership of key initiatives, build shared capabilities and provide expert training and guidance. This is a highly visible role for an experienced scientist who thrives on hands‑on science, collaboration and impact.
What you’ll be doing
- Leading and delivering SCOP research and service projects, owning scientific direction and outcomes.
- Designing and implementing advanced gene editing strategies tailored to project needs.
- Working closely with GeMS and STPs to develop robust, innovative genome engineering solutions.
- Establishing shared methods and technologies with group leaders, strengthening institute capability.
- Staying at the forefront of CRISPR technologies through active horizon scanning and engagement.
- Training and mentoring researchers in gene editing and stem cell culture best practice.
- Engineering and maintaining high‑quality iPSC and ESC lines, ensuring reproducibility and QC.
- Supporting effective lab operations, including SOPs, biosafety, resources and equipment.
- Communicating clearly across teams, contributing to reports, collaboration and supportive research culture.
About you
You will have:
Essential:- A higher degree (MSc or PhD) in a relevant field, with strong research experience in stem cell biology.
- Hands‑on expertise in human pluripotent stem cell culture (iPSC and/or ESC) and core molecular biology techniques.
- Experience designing and delivering gene editing strategies using CRISPR/Cas9 and related technologies.
- Strong experimental design, troubleshooting and data analysis skills, with excellent attention to quality and reproducibility.
- Proven ability to manage multiple projects, work collaboratively and communicate effectively across multidisciplinary teams.
- Experience generating modified pluripotent stem cell lines (e.g. knockouts, knock‑ins, conditional alleles).
- Familiarity with advanced culture systems (e.g. organoids, assembloids) and/or automation tools.
- Knowledge of genome engineering workflows, reprogramming approaches, or bioinformatics tools for guide design and analysis.
About Working at the Crick
Our values: We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We’re not afraid to do things differently. We are open. We’re highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial. We show respect for one another, work cooperatively and support the wider community.
At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences.
What will you receive?
At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well‑being and development:
- Visas: Applicants for this role will be eligible for sponsorship to work in the UK.
- Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays.
- Pension Scheme: Defined contribution pension with employer contributions of up to 16%.
- Health & Well‑being: 24/7 GP consultation services. Occupational health services and mental health support programs. Eye care vouchers and discounted healthcare plans.
- Work‑Life Balance: Back‑up care for dependents. Childcare support allowance. Annual leave purchase options. Crick Networks offering diverse groups’ support, community and inclusive social events.
- Perks: Discounted gym memberships, bike‑to‑work scheme, and shopping discounts. Subsidised on‑site restaurant and social spaces for team interaction.
- Career support: Since September 2017 Crick has been a signatory to the Technician Commitment, an initiative across the research sector to ensure visibility, recognition, career development and sustainability for technicians working in higher education and research, across all disciplines.
Please note you must meet the essential criteria listed within the Role Profile, to have your application reviewed. We reserve the right to withdraw this advert at any given time due to the number of applications received.
Senior Laboratory Research Scientist - Genome Editing in Human Stem Cells employer: Francis Crick Institute
Contact Detail:
Francis Crick Institute Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior Laboratory Research Scientist - Genome Editing in Human Stem Cells
✨Tip Number 1
Network like a pro! Reach out to current or former employees at the Crick Institute on LinkedIn. A friendly chat can give us insider info about the team and culture, plus it might just get your name on the hiring manager's radar.
✨Tip Number 2
Prepare for the interview by diving deep into the latest CRISPR technologies and genome editing strategies. We want to see your passion and knowledge shine through, so brush up on those cutting-edge techniques and be ready to discuss how you can contribute to SCOP.
✨Tip Number 3
Show off your collaborative spirit! During interviews, share examples of how you've worked with multidisciplinary teams in the past. We love candidates who can communicate effectively and foster a supportive research culture.
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets seen. Plus, we’re all about making the process as smooth as possible, so if you need help, just reach out!
We think you need these skills to ace Senior Laboratory Research Scientist - Genome Editing in Human Stem Cells
Some tips for your application 🫡
Tailor Your Application: Make sure to customise your CV and cover letter to highlight your experience in stem cell biology and gene editing. We want to see how your skills align with the role, so don’t hold back on showcasing your hands-on expertise!
Show Off Your Collaboration Skills: Since we value teamwork, it’s important to mention any collaborative projects you've worked on. Share examples of how you’ve communicated effectively across multidisciplinary teams – this will really resonate with us!
Be Clear and Concise: When writing your application, keep it straightforward and to the point. We appreciate clarity, so make sure your key achievements and experiences stand out without unnecessary fluff.
Apply Through Our Website: We encourage you to submit your application through our website for a smoother process. It’s the best way to ensure your application gets into the right hands and is reviewed promptly!
How to prepare for a job interview at Francis Crick Institute
✨Know Your Science
Make sure you brush up on the latest advancements in genome editing and stem cell research. Be prepared to discuss your hands-on experience with iPSC and ESC culture, as well as any CRISPR/Cas9 projects you've led. This will show that you're not just familiar with the theory but have practical expertise.
✨Showcase Collaboration Skills
Since this role involves working closely with multidisciplinary teams, be ready to share examples of how you've successfully collaborated in the past. Highlight any experiences where you’ve partnered with other scientists or departments to achieve a common goal, as this aligns with the Crick's values of openness and collegiality.
✨Prepare for Problem-Solving Questions
Expect questions that assess your experimental design and troubleshooting skills. Think of specific challenges you've faced in your research and how you overcame them. This will demonstrate your ability to manage multiple projects and maintain high-quality standards, which is crucial for this position.
✨Communicate Clearly
Effective communication is key in this role. Practice explaining complex scientific concepts in a clear and concise manner. You might be asked to present your research findings or discuss methodologies, so being articulate will help you stand out as a candidate who can contribute to a supportive research culture.
