Senior Laboratory Research Scientist – Tumour and Host Metabolism Laboratory

Senior Laboratory Research Scientist – Tumour and Host Metabolism Laboratory

Full-Time 47080 - 47080 £ / year (est.) No working from home possible
Francis Crick Institute Ltd

At a Glance

  • Tasks: Design and implement experiments to explore cancer metabolism and cell behaviour.
  • Company: Join the Francis Crick Institute, Europe's largest biomedical research hub.
  • Benefits: Enjoy 28 days annual leave, health support, and a generous pension scheme.
  • Other info: Dynamic environment fostering innovation and career growth opportunities.
  • Why this job: Make a real impact in cancer research with cutting-edge techniques and a collaborative team.
  • Qualifications: PhD in molecular biology or related field with postdoctoral experience.

The predicted salary is between 47080 - 47080 £ per year.

Salary for this Role: From £47,080 with benefits, subject to skills and experience.

Reports to: Karen Vousden

Closing Date: 28th of August 2026 at 23.59pm

Details of the role:

  • Working pattern: This is a full-time, 2 year fixed term position on Crick terms and conditions of employment.

About us:

The Francis Crick Institute is Europe's largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions. The Crick is a place for collaboration, innovation and exploration across many disciplines.

The Research Lab:

We are looking for a Senior Laboratory Research Scientist position to join the Vousden Lab - Tumour and Host Metabolism Laboratory for two years. We focus on how changes in metabolism affect cancer development and progression.

About the role:

You will support several projects aimed at understanding the role of metabolism in controlling various aspects of cancer cell behaviour, such as the regulation of reactive oxygen species (ROS), epithelial to mesenchymal transition and cancer/host cell interactions. This post will be an exciting opportunity to be part of a research group that is focused on investigating how metabolism affects tumour development using various in vitro and in vivo techniques.

What you will be doing:

  • Design and implementation of experiments to assess nutrient and metabolic requirements of cancer cells.
  • Maintain cancer cells in culture and assess growth rates and survival.
  • Perform western blot analysis of protein expression.
  • Reagent preparation, sample accession and preparation.
  • Collaboration and interaction with other group members, as required.
  • General contribution to the smooth running of the lab, including contribution to general lab tasks.
  • Presentation and discussion of results at lab meetings.

About you:

  • PhD (or equivalent experience) in the area of molecular biology, cancer models and metabolism.
  • Understanding of oxidative stress and ROS.
  • Technical metabolomic or proteomic analysis.
  • At least 3 years postdoctoral experience (or equivalent experience).
  • Track record of writing papers as evidenced by publications or submitted manuscripts in refereed journals.
  • Evidence of data presentation at scientific meetings.
  • Experience of experimental design.
  • Ability to work independently and also capable of interacting within a group.
  • Metabolic pathway analysis (desirable).

About Working at the Crick:

Our values: Everyone who works at the Crick has a valuable role to play in advancing the Crick's mission and shaping our culture. We are bold, open, and collegial. At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery.

What will you receive?

  • Visas: Applicants for this role will be eligible for sponsorship to work in the UK.
  • Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays.
  • Pension Scheme: Defined contribution pension with employer contributions of up to 16%.
  • Health & Well-being: 24/7 GP consultation services, occupational health services and mental health support programs.
  • Work-Life Balance: Back-up care for dependents, childcare support allowance, annual leave purchase options.
  • Perks: Discounted gym memberships, bike-to-work scheme, and shopping discounts.

The Francis Crick Institute is a biomedical discovery institute researching the biology underlying human health.

Senior Laboratory Research Scientist – Tumour and Host Metabolism Laboratory employer: Francis Crick Institute Ltd

The Francis Crick Institute is an exceptional employer, offering a vibrant and collaborative work culture that fosters innovation and exploration in biomedical research. With generous benefits including 28 days of annual leave, a robust pension scheme, and comprehensive health and well-being support, employees are empowered to thrive both personally and professionally. The institute's commitment to diversity and inclusion, alongside opportunities for meaningful impact within a world-class organisation, makes it an attractive place for those seeking to contribute to groundbreaking scientific advancements.

Francis Crick Institute Ltd

Contact Details:

Francis Crick Institute Ltd Recruitment Team

We think you need these skills to ace Senior Laboratory Research Scientist – Tumour and Host Metabolism Laboratory

Molecular Biology
Cancer Models
Metabolism Analysis
Oxidative Stress Understanding
Technical Metabolomic Analysis
Proteomic Analysis
Experimental Design