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- Tasks: Join us to explore cancer evolution and contribute to groundbreaking research in lung cancer.
- Company: The Francis Crick Institute is Europe's largest biomedical research hub, driving innovation in health sciences.
- Benefits: Enjoy 28 days of leave, health support, gym discounts, and a collaborative work environment.
- Why this job: Be part of a dynamic team tackling crucial scientific questions with cutting-edge technology.
- Qualifications: PhD required; experience in cancer genomics, R or Python proficiency, and a collaborative spirit needed.
- Other info: We value diversity and encourage applications from all backgrounds; reasonable adjustments available.
The predicted salary is between 38500 - 50500 £ per year.
Postdoctoral Project Research Scientist – (C Swanton) Cancer Evolution and Genome Instability Laboratory page is loaded
Postdoctoral Project Research Scientist – (C Swanton) Cancer Evolution and Genome Instability Laboratory
Apply locations London time type Full time posted on Posted Yesterday job requisition id R2341
Salary for this Role:
From £45,500 with benefits, subject to skills and experience.
Job Title:
Postdoctoral Project Research Scientist – (C Swanton) Cancer Evolution and Genome Instability Laboratory
Reports to:
Charles Swanton (C)
Closing Date:
11/Aug/2025 23.59 GMT
Job Description:
Postdoctoral Project Research Scientist – (C Swanton) Cancer Evolution and Genome Instability Laboratory
Reporting to: Charles Swanton, Principal Investigator, Deputy Clinical Director
Contact term: This is a full-time 2 year position on Crick terms and conditions of employment.
About us
The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.
The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We’ve removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy.
About the role
Our research direction investigates the role of cell lineage upon lung cancer initiation, both in homeostasis and in the context of challenge with non-mutagenic carcinogens.
Our research is committed to advancing our understanding the biology of lung tumour evolution based around analysis of next generation sequence (NGS) data and the tumour microenvironment from the TRACERx longitudinal lung cancer program. Leveraging genomic, transcriptomic and epigenomic sequencing as well as spatial immunophenotyping data from patient samples, our aim is to trace the intricate evolutionary trajectories of lung tumours across space and time. This work will unveil the key drivers of cancer progression, immune resistance mechanisms, and potential vulnerabilities within the tumour landscape.
As a Postdoctoral Project Research Scientist in the Swanton lab, your main responsibilities will be to work with the informatics team on TRACERx project, whilst also contributing to other projects throughout the lab. If you have experience in Bioinformatics, are fluent in R or Python as well as experience in evolutionary or cancer biology, we would love to hear from you.
Please see the full job description here.
See more about the lab here.
What you will be doing
As a Postdoctoral Project Research Scientist at the Crick, some of your main responsibilities will be:
- To decipher evolutionary mechanisms during lung cancer initiation and progression.
- To employ novel informatics techniques based on evolutionary principles to the analysis of tumour subclonal evolution.
- To understand cancer biology and the relevant literature sufficiently to take own ideas forward as lead author on new projects.
- To work within the informatics team of the TRACERx and TRACERx EVO programs.
- To record all experiments and code in an accurate timely, clearly presented and reproducable manner, and use this to prepare data summaries and reports as and when required.
- To attend, and report research results at regular group and external meetings.
- To contribute to the dissemination of scientific results by means of writing papers for publication, and presenting orally and in poster form at national and international meetings.
About you
You will have:
- PhD
- Previous experience with cancer genomics NGS data
- Fluent in R or Python
- Evidence of significant contribution to high impact publications
- Experience with HPC environments
- Experience of collaboration with clinicians and wet lab scientists or work within a multi-disciplinary environment
About Working at the Crick
Our values
Everyone who works at the Crick has a valuable role to play in advancing the Crick’s mission and shaping our culture!
- We arebold . We make space for creative, dynamic and imaginative ideas and approaches. We’re not afraid to do things differently.
- We areopen . We’re highly collaborative and interactive, and make sure our activities are visible to the outside world.
- We arecollegial . We show respect for one another, work cooperatively and support the wider community.
At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances. We actively encourage applications from individuals of all genders, ethnicities, abilities, and experiences. Weare aDisability Confident: Committed employer andwant to ensure that everyone can apply and be part of our recruitment processes and sowe\’llmake reasonable adjustments if you need them – just let us know when you apply. If you needassistancewith applying (i.e., would like to apply by phone or post) please email:
Find out more about life at the Crick.
What will you receive?
At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development:
- Visas: Applicants for this role will be eligible for sponsorship to work in the UK
- Generous Leave : 28 days of annual leave, plus three additional days over Christmas and bank holidays.
- Pension Scheme : Defined contribution pension with employer contributions of up to 16%.
- Health & Well-being :
- 24/7 GP consultation services.
- Occupational health services and mental health support programs.
- Eye care vouchers and discounted healthcare plans.
- Work-Life Balance :
- Back-up care for dependents.
- Childcare support allowance.
- Annual leave purchase options.
- Crick Networks offering diverse groups’ support, community and inclusive social events.
- Perks :
- Discounted gym memberships, bike-to-work scheme, and shopping discounts.
- Subsidised on-site restaurant and social spaces for team interaction.
Please note you must meet the essential criteria listed within the Role Profile, to have your application reviewed.
We reserve the right to withdraw this advert at any given time due to the number of applications received.
About Us
The Francis Crick Institute is a biomedical discovery institute researching the biology underlying human health.
At the Crick, scientists and staff collaborate to stretch the very limits of what we know about how life works. Our work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections and neurodegenerative diseases.
The Francis Crick Institute is a charity, founded by the Medical Research Council, Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London.
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Postdoctoral Project Research Scientist – [C Swanton] Cancer Evolution and Genome Instability L[...] employer: Francis Crick Institute Ltd
Contact Detail:
Francis Crick Institute Ltd Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Postdoctoral Project Research Scientist – [C Swanton] Cancer Evolution and Genome Instability L[...]
✨Tip Number 1
Network with professionals in the field of cancer research and bioinformatics. Attend relevant conferences or seminars where you can meet researchers from the Crick Institute or similar institutions. This can help you gain insights into their work and potentially lead to valuable connections.
✨Tip Number 2
Familiarise yourself with the latest research and publications from the Swanton lab and the TRACERx project. Understanding their current projects and methodologies will allow you to speak knowledgeably about how your skills and experiences align with their goals during interviews.
✨Tip Number 3
Demonstrate your coding skills in R or Python by working on relevant projects or contributing to open-source initiatives. Having a portfolio of your work can showcase your abilities and make you stand out as a candidate who is proactive and skilled.
✨Tip Number 4
Prepare for potential interviews by practising answers to common questions related to cancer biology and bioinformatics. Be ready to discuss your previous research experiences and how they relate to the role, as well as your approach to collaboration within multidisciplinary teams.
We think you need these skills to ace Postdoctoral Project Research Scientist – [C Swanton] Cancer Evolution and Genome Instability L[...]
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights relevant experience in bioinformatics, cancer genomics, and programming languages like R or Python. Emphasise any significant contributions to high-impact publications.
Craft a Compelling Cover Letter: In your cover letter, express your passion for cancer research and how your background aligns with the goals of the Swanton lab. Mention specific projects or techniques you are excited about and how you can contribute.
Highlight Collaborative Experience: Since the role involves working within a multi-disciplinary environment, be sure to showcase any previous collaborations with clinicians or wet lab scientists. This will demonstrate your ability to work effectively in a team.
Proofread and Format: Before submitting your application, carefully proofread all documents for spelling and grammatical errors. Ensure that your formatting is consistent and professional, making it easy for the hiring team to read.
How to prepare for a job interview at Francis Crick Institute Ltd
✨Know Your Research
Familiarise yourself with the latest research in cancer evolution and genome instability. Be prepared to discuss how your previous work aligns with the lab's focus, particularly on lung cancer and NGS data analysis.
✨Demonstrate Technical Skills
Since the role requires proficiency in R or Python, be ready to showcase your coding skills. You might be asked to solve a problem or explain your approach to data analysis during the interview.
✨Prepare for Collaborative Questions
Expect questions about your experience working in multidisciplinary teams. Highlight any collaborations with clinicians or wet lab scientists, as this is crucial for the role.
✨Showcase Your Publications
Be ready to discuss your contributions to high-impact publications. This will demonstrate your ability to produce quality research and your understanding of the publication process in scientific communities.