Research Associate in Chemical Proteomics (10391)

The Rosalind Franklin Institute (the Franklin) is a technology institute established by the UK Government as a unique centre committed to advancing tools that are needed to transform healthcare in the future. The Institute brings together researchers in life and physical sciences, and engineering, to develop a spectrum of tools which we will use to image, interpret and intervene in biological systems. These insights will speed up the discovery of new medicines, help find new diagnostics and contribute to a deeper understanding of human health and disease.

As a Research Associate in Chemical Proteomics at the Franklin, you will bring scientific knowledge and skills to deliver a specific research project and/or you will bring independent, creative science, or specific skills to a team delivering a project or program. Through this work, you will build scientific independence, develop new science and leadership skills, and establish a growing reputation externally.

• Carry out analytical procedures that are applied for proteome characterisation to a high degree of precision, including sample preparation.
• Analyse and interpret quantitative proteomic data with a degree of statistical rigour using common freely available software packages.
• Help to devise then create proteomic methodologies (sample preparation, liquid chromatography (LC) and mass spectrometry) to address specific biological questions.
• Act as a source of information and advice to other members of the group on scientific protocols and experimental techniques.
• Assist with general laboratory maintenance including the troubleshooting and upkeep of nanoLCs, centrifugal evaporators, liquid handlers, and various MS equipment.
• Help devise methods (with others at the Franklin) for supporting an increasingly diverse set of sample sources including those from cell lines, cell samples, tissue samples and organoids.
• Work alongside the proteomics facility to ensure upkeep of nanoLCs, centrifugal evaporators, liquid handlers and various other MS equipment.
• Help liaise with the laboratory support and service staff, engineers, and scheduling servicing. This will include essential day‑to‑day maintenance, troubleshooting and minor servicing to ensure continuous operation.
• Enhance your research through collaboration with other researchers and make active contributions to exchanging of ideas through your own network.
• Work within a larger project team, contributing to Institute wide projects around key Franklin Challenges.
• Work together with the surrounding facilities to ensure efficient methods at the Franklin and Harwell environment.
• Publish research articles in leading academic journals.
• Present findings at national and international meetings/conferences.
• Support and develop others including day‑to‑day supervision of students or visitors in areas related to your research.
• Participate in and support the public engagement and widening access activities of the Franklin.
• Carry out any other duties that come up in the normal running of the facility and that can be reasonably requested of the post‑holder.

Whilst the role requires candidates to hold a PhD/DPhil (or equivalent), we may consider candidates who have submitted their PhD/DPhil thesis, in which case the initial appointment will be made at £37,500 per annum (to be increased on completion of the PhD/DPhil qualification). We are particularly interested in candidates who can deliver the responsibilities outlined above and are eager to contribute to the development of innovative mass‑spectrometry methodologies.

• 25 days holidays plus bank holidays and Christmas holiday shutdown
• Generous pension scheme (employer’s contribution currently up to 18%)
• Group Life Assurance
• Buying and Selling Annual Leave
• Workplace Nursery
• Salary Sacrifice Scheme
• Hub building with state‑of‑the‑art laboratories
• Hybrid and flexible working
• Training and development opportunities for staff at all levels
• Bus pass discount scheme and good transport links to Oxford and surrounding areas
• Cycle to Work Scheme
• Access to employee discount platform (Perkbox)
• Occupational Health and wellbeing support including Employee Assistance (24/7 support and counselling)
• Health Cash Plan
• Subsidised canteen and food outlets on campus
• Free on‑site parking
• Campus location in beautiful countryside with social and sports clubs open to staff

The closing date for applications is 23:59 on Sunday 29th March 2026. To be considered for this role, please submit a CV and cover letter explaining why you think you are the right person for this job. Please include information about your education and work experience. We are committed to creating an inclusive environment where every applicant has an equal opportunity to showcase their talents and abilities. This includes making adjustments for candidates with specific needs. Please contact us at [emailprotected] to discuss your requirements confidentially.