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- Tasks: Lead groundbreaking research on RNAi and its role in fungal adaptation.
- Company: Join the innovative Quadram Institute, a leader in gut health research.
- Benefits: Competitive salary, collaborative environment, and opportunities for professional growth.
- Why this job: Make a real impact in science while working with top researchers globally.
- Qualifications: PhD in Genetics or Molecular Biology with strong RNAi and epigenetics knowledge.
- Other info: Dynamic, inclusive workplace with a commitment to diversity and equity.
The predicted salary is between 37500 - 45350 £ per year.
We are seeking an enthusiastic Research Scientist to join the Buscaino Laboratory at the Quadram Institute. This Wellcome Trust–funded project investigates how RNA interference (RNAi) regulates Candida albicans adaptation to host environments and contributes to the commensal to pathogen transition. This position is highly collaborative and contributes to a multidisciplinary effort to uncover how RNAi coordinates chromatin structure, genome stability and transcriptional responses during adaptation.
The post holder will support other lab members, troubleshoot and contribute to collaborative data interpretation, and participate in scientific publications and conference presentations. The post holder will be based at the Quadram Institute and will work closely with Prof Alessia Buscaino and members of her research group, as well as collaborating with two external partners: Prof Kevin Foster (University of Oxford) and Prof Ana Traven (Monash University).
The role:
- Lead experimental work integrating (epi)genomics and genetics approaches to determine how RNAi shapes genome organization and interacts with other epigenetic processes to facilitate fungal adaptation.
- Conduct chromatin profiling experiments (e.g., ChIP-seq, ATAC-seq) and Hi-C analysis in wild-type and RNAi-defective strains under different host-relevant gut conditions.
- Investigate how RNAi contributes to reversible, non-DNA-encoded regulation of gene expression.
- Generate and analyze RNAi mutants using molecular genetics; collaborate with the team’s bioinformatician to design robust genomics and epigenomics strategies.
- Contribute to scientific publications, conference presentations and the dissemination of findings at national and international meetings.
The ideal candidate:
- PhD in Genetics, Molecular Biology or related disciplines.
- Strong understanding of RNAi biology coupled with a solid foundation in epigenetics.
- Practical experience with genetic manipulation, including generating mutants and conducting functional assays.
Additional information:
- Salary on appointment within the range £37,500 to £45,350 per annum, depending on qualifications and experience.
- Full-time post for a contract of 24 months.
- This role meets the criteria for a visa application; qualified candidates are encouraged to apply.
- We are committed to equity, diversity and inclusion, and welcome applications from all sectors of society.
- The Institute values Respect, Innovation, Collaboration and Excellence, and we expect all employees to share and display these values.
- As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.
About the Quadram Institute: The Quadram Institute is a new interdisciplinary research institute dedicated to understanding how food and microbes interact to promote health and prevent disease. Its mission is to deliver healthier lives through innovation in gut health, microbiology and food.
The closing date for applications is 12 February 2026.
Research Scientist (RNAi Epigenetics) in London employer: Findauniversity Ltd.
Contact Detail:
Findauniversity Ltd. Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Research Scientist (RNAi Epigenetics) in London
✨Tip Number 1
Network like a pro! Reach out to current or former employees at the Quadram Institute on LinkedIn. A friendly chat can give us insider info about the lab culture and maybe even a referral!
✨Tip Number 2
Prepare for that interview! Brush up on your RNAi knowledge and be ready to discuss your past research experiences. We want to see how you can contribute to the team, so think of examples that showcase your skills.
✨Tip Number 3
Show your enthusiasm! When you get the chance to speak with the hiring team, let your passion for epigenetics and RNAi shine through. We love candidates who are genuinely excited about the work we do!
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets seen. Plus, it shows us you’re serious about joining the Quadram Institute family.
We think you need these skills to ace Research Scientist (RNAi Epigenetics) in London
Some tips for your application 🫡
Tailor Your CV: Make sure your CV is tailored to highlight your experience in RNAi biology and epigenetics. We want to see how your skills align with the role, so don’t be shy about showcasing relevant projects or research!
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to express your enthusiasm for the project and the collaborative nature of the role. Let us know why you’re excited about joining the Buscaino Laboratory and how you can contribute.
Showcase Your Collaborative Spirit: Since this position involves working closely with other researchers, make sure to highlight any past collaborative experiences. We love seeing how you’ve worked with others to achieve common goals in your previous roles.
Apply Through Our Website: Don’t forget to apply through our website! It’s the best way to ensure your application gets to us directly. Plus, it helps us keep track of all the amazing candidates like you who are interested in joining our team.
How to prepare for a job interview at Findauniversity Ltd.
✨Know Your RNAi Inside Out
Make sure you brush up on your understanding of RNA interference and its role in epigenetics. Be ready to discuss how it relates to Candida albicans and the specific experiments you might conduct, like ChIP-seq or Hi-C analysis.
✨Show Off Your Collaborative Spirit
Since this role is highly collaborative, think of examples from your past experiences where you've worked well in a team. Highlight how you supported others and contributed to joint projects, as this will resonate with the lab's culture.
✨Prepare for Technical Questions
Expect to be asked about your practical experience with genetic manipulation and functional assays. Be prepared to discuss specific techniques you've used, any challenges you faced, and how you overcame them.
✨Align with Their Values
Familiarise yourself with the Quadram Institute's values of Respect, Innovation, Collaboration, and Excellence. Think of ways you can demonstrate these values through your work ethic and past experiences during the interview.
