Senior Scientist (Expression) in Macclesfield

We are currently recruiting for an experienced Senior Scientist (Expression) to join our Protein Sciences Team.

Our Company

Evotec is a leader in the discovery and development of novel small molecule drugs with operational sites in Europe and the US. The Company has built substantial drug discovery expertise and an industrialised platform that can drive new innovative small molecule compounds into the clinic. In addition, Evotec has built a deep internal knowledge base in the treatment of diseases related to neuroscience, pain, oncology, inflammation and metabolic diseases. Leveraging these skills and expertise the Company intends to develop best-in-class differentiated therapeutics and deliver superior science-driven discovery alliances with pharmaceutical and biotechnology companies.

Purpose of the Role

Responsible for establishing and execution of work plans for their protein science area. Accountable for protein science Project delivery from early drug discovery projects in their area of expertise, across modalities and therapeutic areas.

Key Accountabilities

• Design and execution of agreed work plans for early drug discovery projects.
• Responsible for supporting more than one project and may be asked to direct internal resources to achieve agreed goals.
• Will be expected to provide oversight of results to ensure quality to project specifications.
• Accountable, together with project counterparts, for the design of experiment, review of documentation and client presentations. Will conduct thorough data analysis ahead of product release to internal or external customers.
• Proposes experimental designs and novel approaches to identify/advance best strategies in addition to planning/executing project deliverables.
• Responsible for the implementation of standalone scientific services and deliverables to customers.
• Where responsible for reports will lead colleagues to co-develop plans for personal growth, aligned to business need.
• Represent the company at scientific and/or business conferences.
• Presents and publishes as appropriate peer-reviewed science increasing own and Evotec’s scientific reputation.

Knowledge & Experience

• Strong technical knowledge of Protein Biochemistry, Structural Biology or Biophysics with a proven ability to design and deliver results across target families within agreed timelines and budget, meeting agreed quality criteria.
• Design, clone, and optimise expression constructs for recombinant protein production in E. coli, insect (Baculovirus and S2), and mammalian systems.
• Execute small‐ to large‐scale expression experiments to maximise yield, solubility, and functionality.
• Assess quality via SDS‐PAGE, Western blot, and related analytics.
• Troubleshoot complex expression challenges with creative, data‐driven solutions.
• Experience of preparing and executing workplans and building trusted partnership with internal and external customers.
• Requires a track record of leading scientists across specialist fields.
• Requires a track record of facilitating employee growth through co-development of PDP.
• Track record of successful problem-solving, high-quality science and influencing of stakeholders and colleagues.
• Experience of scientific development and research work ideally with publications in a relevant scientific field.

Education and Qualifications

• Ph.D. degree or corresponding experience in a relevant scientific discipline with some relevant experience in industry.
• Alternatively, a relevant first degree and additional experience within drug discovery.

Evotec Leadership Competencies

• Understanding: Starts conducting more research and recognizes threats, trends, and changing circumstances; can articulate strategic assumptions.
• Beginning Risk-Taking: Willing to take small risks but often requires reassurance and support; hesitant to fully embrace innovative approaches.
• Emerging Initiative: Shows emerging initiative in driving outcomes, occasionally needs support and direction.
• Active Communication: Communicates actively, working on further clarity and responsiveness.
• Constructive Feedback: Actively seeks and provides constructive feedback, using it to improve processes and outcomes.
• Solid Team Interaction: Engages with the team regularly; further building out clarity and purpose of the interactions.
• Occasional Planning: Begins anticipating problems and improves on proactively taking precautions.

Benefits Package

• Pension on completion (but not subject to) of your 3-month probationary period. Contributions 5% for employees (salary sacrifice) and 5% for the employer. The employee can opt to increase their contribution, and the employer will match the increase up to a maximum of 7.5%.
• 25 days holiday plus bank holidays and additional length of service days awarded on the anniversary, up to a maximum of 30 days.
• Private health insurance with BUPA for the employee and their partner/family under the company scheme.
• Well being support 24/7 and counselling services.
• Permanent health insurance provides 75% of the base salary after the qualifying period.
• Private dental cover, on completion (but not subject to) of your 3-month probationary period.
• Eligibility to participate in the Company Bonus Scheme. This is a discretionary benefit.
• Career progression within the company, we have excellent training and support and continuing professional development opportunities.
• Cycle-to-work scheme.
• Refer a friend scheme, team and annual events, recognition awards and many more!

Onsite Facilities

• The company pays for secure onsite parking.
• Restaurant, Café, and Gastro pub.
• Gym and workout studio, running, walking, and cycling routes.
• Good public transport links with the shuttle bus service.