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- Tasks: Lead antibody screening and characterisation for transformative therapeutics in fibrosis and oncology.
- Company: Engitix Therapeutics, a pioneering biotech company in West London.
- Benefits: Join a mission-driven team with opportunities for impactful work and career growth.
- Other info: Dynamic environment focused on innovation and collaboration.
- Why this job: Make a real difference in developing therapies for life-threatening diseases.
- Qualifications: PhD or MSc with relevant experience in drug screening and antibody development.
The predicted salary is between 48000 - 72000 ÂŁ per year.
Your Mission Engitix Therapeutics is a pioneering biotech company dedicated to unlocking extracellular matrix biology to develop transformative therapeutics in fibrosis and oncology.
We are seeking an accomplished Senior Scientist of Antibody Screening to play a lead role in selecting and characterising therapeutic antibody drug candidates. You will utilise your expertise to establish screening cascades for characterising the antibody hits in drug discovery programs. Demonstrable experience of binding assays in multiple formats and in SPR is essential. Further expertise in cell‑based assays, epitope binning and/or developability profiling would be desirable.
Key Responsibilities- Establish hit‑to‑lead screening cascade assays to identify potent, functional and developable monoclonal antibodies, driving project progression through key milestones.
- Perform lab‑based binding assays, including ELISA and SPR.
- Manage CROs for antibody production and/or other antibody‑related activities.
- Analyse, interpret, report and present results in project meetings.
- PhD in Biomedical Sciences, Immunology, Biochemistry, Biotechnology, or a related discipline, plus 3 years’ experience in a drug screening environment; or an MSc plus 6 years of practical experience with a focus on immuno‑oncology or fibrosis.
- Familiarity with antibody drug development is essential, as is prior working experience in the biotech/pharma industry.
- Ability to work under pressure in a fast‑paced, biotech environment.
- Ability to plan, execute, and critically assess experiments independently.
- Excellent time‑management skills and ability to work to set deadlines.
- Excellent written and verbal communication skills and the ability to work effectively within a team.
- Strong troubleshooting skills, with a methodical approach, high attention to detail, and the ability to maintain accurate records.
- Fc effector function cell‑based assays for ADCP, ADCC and CDC.
- Experience of primary cell culture for cell types relevant to fibrosis and oncology research.
- High‑throughput screening approaches (e.g. 384‑well format).
- Epitope binning and/or antigen‑antibody characterisation approaches.
- Antibody developability profiling.
About Us Engitix is a growing biotech company based in White City Place, West London. We are dedicated to developing better therapies for advanced fibrosis and solid tumours by leveraging our pioneering extracellular matrix (ECM) platform. Our platform allows the synthesis of realistic in‑vitro 3D models that serve as tools to transform our ability to identify new targets and biomarkers, determine mechanisms of action and more accurately predict the efficacy of therapeutic candidates. Join us today in our mission to create a healthier future for patients with life‑threatening diseases such as fibrosis and cancer.
Senior Scientist, Antibody Screening employer: Engitix Therapeutics
Contact Detail:
Engitix Therapeutics Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior Scientist, Antibody Screening
✨Network Like a Pro
Get out there and connect with people in the biotech field! Attend industry events, join relevant online forums, and don’t be shy about reaching out to professionals on LinkedIn. We all know that sometimes it’s not just what you know, but who you know that can help you land that dream job.
✨Show Off Your Skills
When you get the chance to chat with potential employers, make sure to highlight your hands-on experience with binding assays and SPR. We want to see how your expertise can directly contribute to their projects. Be ready to discuss specific examples of your work and how it aligns with their mission.
✨Prepare for the Interview
Do your homework on Engitix and their innovative ECM platform. We recommend preparing thoughtful questions about their current projects and challenges in antibody screening. This shows you’re genuinely interested and ready to dive into their work culture.
✨Apply Through Our Website
Don’t forget to apply through our website! It’s the best way to ensure your application gets seen by the right people. Plus, we love seeing candidates who take the initiative to engage directly with us. Let’s make this happen together!
We think you need these skills to ace Senior Scientist, Antibody Screening
Some tips for your application 🫡
Tailor Your CV: Make sure your CV is tailored to highlight your experience in antibody screening and drug discovery. We want to see how your skills align with our mission at Engitix, so don’t hold back on showcasing relevant projects!
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you’re passionate about our work in fibrosis and oncology. Let us know how your background makes you the perfect fit for the Senior Scientist role.
Showcase Your Achievements: When detailing your experience, focus on specific achievements in your previous roles. We love numbers and results, so if you’ve improved processes or led successful projects, make sure to highlight those!
Apply Through Our Website: We encourage you to apply directly through our website. It’s the best way for us to receive your application and ensures you’re considered for the role. Plus, it shows you’re keen on joining our team!
How to prepare for a job interview at Engitix Therapeutics
✨Know Your Antibodies
Make sure you brush up on your knowledge of antibody drug development and the specific assays mentioned in the job description. Be ready to discuss your experience with binding assays, SPR, and any relevant techniques you've used in past roles.
✨Showcase Your Problem-Solving Skills
Prepare examples that highlight your troubleshooting abilities and methodical approach to experiments. Think of specific challenges you've faced in the lab and how you overcame them, especially in high-pressure situations.
✨Communicate Clearly
Since excellent communication skills are essential for this role, practice explaining complex scientific concepts in a clear and concise manner. You might be asked to present your past work, so make sure you can articulate your findings effectively.
✨Demonstrate Team Spirit
Engitix values teamwork, so be prepared to discuss how you've collaborated with others in previous projects. Share examples of how you contributed to team success and how you handle feedback and differing opinions.