At a Glance
- Tasks: Develop and optimise assays to support drug discovery in fibrosis and oncology.
- Company: Engitix Therapeutics, a pioneering biotech company in West London.
- Benefits: Join a mission-driven team with opportunities for impactful research and career growth.
- Other info: Collaborative environment focused on innovation and patient health.
- Why this job: Make a real difference in developing transformative therapies for serious diseases.
- Qualifications: PhD or MSc with relevant experience in drug discovery and assay development.
The predicted salary is between 40000 - 55000 € per year.
Your mission is to contribute to Engitix Therapeutics, a pioneering biotech company dedicated to unlocking extracellular matrix (ECM) biology to develop transformative therapeutics in fibrosis and oncology. We are seeking an accomplished Scientist to play a key role in the development and execution of biochemical and cell-based assays to support drug discovery activities. This is an exciting fully lab-based role in which we are looking for a scientist with strong experience in assay development within a drug discovery setting.
You will contribute across the discovery cascade, from target validation through to biologics/small molecule profiling, to enable progression of therapeutic programmes. In this role you will apply innovative experimental approaches to interrogate pathway biology, validate novel targets, and characterise candidate drugs in fibrosis and oncology. Interest or experience in ECM biology is highly desirable.
Key Responsibilities- Apply a range of molecular, cellular, and biochemical techniques to investigate mechanism of action and pathway biology
- Design, develop, optimise, and troubleshoot robust biochemical and cell-based assays to support target validation, screening, and biologics / small molecule characterisation
- Perform pharmacological profiling of compounds, including dose-response studies and data interpretation (e.g. IC₅₀/EC₅₀ analysis)
- Establish and maintain mono and co-cultures of primary cells and cell lines
- Contribute to ongoing research on oncology and fibrosis drug discovery projects
- Independently analyse, interpret, report and present results
- Demonstrable experience in cell-based and biochemical assay development within a drug discovery context
- Experience generating and interpreting pharmacological data (e.g. dose-response analysis)
- Experience working with primary cells and/or complex cellular systems (e.g. co-cultures)
- Hands-on experience of relevant techniques such as qRT-PCR, ELISA/Luminex/MSD, western blotting, flow cytometry and cell-based functional assays
- Practical experience in either immuno‑oncology or fibrosis would be an advantage
- Prior industry experience in biotech/pharma (2+ years) is strongly preferred
- PhD in Biomedical sciences, Immunology, Biochemistry, Biotechnology or related discipline or MSc plus 2 years practical experience in cellular/molecular biology, molecular pharmacology or cancer/fibrosis biology
- The post holder will be good at troubleshooting, methodical, well organised, pay close attention to detail, and maintain accurate records
- Able to plan, execute and critically assess experiments independently
- Excellent time‑management skills and ability to work to set deadlines
- Work well within a team and in matrix environment, with strong written and verbal communication skills
About Us: Engitix is a growing biotech company based in White City Place, West London. We are dedicated to developing better therapies for advanced fibrosis and solid tumours by leveraging our pioneering extracellular matrix (ECM) platform. Our platform allows the synthesis of realistic in vitro 3D models that serve as tools to transform our ability to identify new targets and biomarkers, determine mechanisms of action and more accurately predict the efficacy of therapeutic candidates. Join us today in our mission to create a healthier future for patients with life‑threatening diseases such as fibrosis and cancer.
Scientist, Drug Discovery employer: Engitix Therapeutics
Engitix Therapeutics is an exceptional employer, offering a dynamic work environment in the heart of West London where innovation thrives. As a growing biotech company, we provide our scientists with unparalleled opportunities for professional development and collaboration on groundbreaking projects in drug discovery, particularly in fibrosis and oncology. Our commitment to fostering a supportive culture, combined with access to cutting-edge technology and resources, makes Engitix an ideal place for those looking to make a meaningful impact in healthcare.
StudySmarter Expert Advice🤫
We think this is how you could land Scientist, Drug Discovery
✨Tip Number 1
Network like a pro! Reach out to people in the biotech field, especially those working in drug discovery. Attend industry events or webinars, and don’t be shy about asking for informational interviews – you never know who might have a lead on your dream job!
✨Tip Number 2
Show off your skills! When you get the chance to chat with potential employers, be ready to discuss your hands-on experience with techniques like qRT-PCR or flow cytometry. Share specific examples of how you've tackled challenges in assay development – it’ll make you stand out!
✨Tip Number 3
Don’t just apply anywhere; focus on companies that align with your passion for ECM biology and drug discovery. Use our website to find roles that excite you, and tailor your approach to highlight how your background fits their mission.
✨Tip Number 4
Prepare for interviews by brushing up on your knowledge of oncology and fibrosis. Be ready to discuss recent advancements in these areas and how they relate to the role. Showing that you’re informed and enthusiastic can really impress hiring managers!
We think you need these skills to ace Scientist, Drug Discovery
Some tips for your application 🫡
Tailor Your CV:Make sure your CV is tailored to the Scientist role at Engitix. Highlight your experience in assay development and any relevant techniques you've mastered. We want to see how your background aligns with our mission in drug discovery!
Craft a Compelling Cover Letter:Your cover letter is your chance to shine! Use it to explain why you're passionate about ECM biology and how your skills can contribute to our projects. Keep it engaging and personal – we love to see your enthusiasm!
Showcase Relevant Experience:When detailing your experience, focus on specific projects or roles where you developed biochemical and cell-based assays. We’re looking for concrete examples that demonstrate your expertise in drug discovery and pharmacological profiling.
Apply Through Our Website:We encourage you to apply directly through our website. It’s the best way to ensure your application gets into the right hands. Plus, it shows us you’re serious about joining our team at Engitix!
How to prepare for a job interview at Engitix Therapeutics
✨Know Your Assays
Make sure you brush up on your knowledge of biochemical and cell-based assays. Be ready to discuss specific techniques you've used, like qRT-PCR or ELISA, and how they relate to drug discovery. This will show that you’re not just familiar with the theory but have hands-on experience.
✨Showcase Your Problem-Solving Skills
Prepare examples of how you've tackled challenges in assay development or data interpretation. Highlight your troubleshooting abilities and how you’ve optimised protocols in previous roles. This will demonstrate your methodical approach and attention to detail.
✨Understand ECM Biology
Since interest in ECM biology is highly desirable, do some research on its role in fibrosis and oncology. Be prepared to discuss how this knowledge can contribute to the company’s mission and how you can apply it in your work.
✨Communicate Effectively
Practice articulating your research findings clearly and concisely. You might be asked to present results or explain complex concepts, so being able to communicate effectively is key. Think about how you can convey your ideas in a way that’s engaging and easy to understand.
