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- Tasks: Conduct histology and tissue studies to validate therapeutic targets in disease models.
- Company: Engitix Therapeutics, a pioneering biotech focused on transformative therapies.
- Benefits: Join a mission-driven team with state-of-the-art labs and impactful projects.
- Why this job: Make a real difference in drug discovery for fibrosis and oncology patients.
- Qualifications: PhD in relevant field and 3-5+ years of industry experience required.
- Other info: Dynamic environment with opportunities for professional growth and collaboration.
The predicted salary is between 36000 - 60000 ÂŁ per year.
Engitix Therapeutics is a pioneering biotech dedicated to unlocking extracellular matrix biology to develop transformative therapies in fibrosis and oncology. We are seeking a Scientist or Senior Scientist (12âmonth fixedâterm contractor) to provide expert histology and tissueâbased target validation support across our discovery pipeline.
Your mission
In this role, you will apply histology, immunohistochemistry and immunofluorescence approaches to characterise therapeutic targets in diseaseârelevant models and human tissues. Your work will generate highâquality data to support discovery programmes and inform decision making. This is an exciting opportunity for an experienced industry scientist to contribute handsâon, impactful science across multiple programs in a dynamic biotech environment.
Key Responsibilities
- Design and execute experiments to confirm and characterise therapeutic target expression using tissueâbased approaches.
- Lead handsâon delivery of histology, immunohistochemistry (IHC) and immunofluorescence studies to assess target expression, localisation, and regulation in diseaseârelevant models and human tissues.
- Analyse, interpret and present histological data to support target validation and discovery decision making.
- Optimise and apply advanced tissue technologies such as multiplex IF, digital pathology and image analysis workflows.
- Maintain robust, reproducible and well documented histology workflows.
- Ensure high standards of data integrity, quality and traceability in line with Engitix standards.
- Provide histology expertise to discovery teams, working closely with biologists, programme leads and data scientists.
- Communicate results clearly to internal stakeholders to support scientific decisions.
Education
PhD (or equivalent experience) in Molecular Biology, Cell Biology, Pathology, or related discipline.
Experience
- 3-5+ years' experience in the biotechnology or pharmaceutical industry (Scientist: 3+ years; Senior Scientist 5+ years), with strong handsâon expertise in histology and tissueâbased target expression studies.
- Experience supporting drug discovery programmes with histological data.
- Practical experience with digital pathology and image analysis platforms (e.g. HALO, Visiopharm and Vectra).
- A strong understanding of relevant regulations and ethical guidelines related to biospecimen research, including HTA and GDPR requirements.
Skills
- Execution: Delivers reproducible highâquality data.
- Scientific Judgement: Applies histology expertise to guide experiments and interpret data.
- Collaboration & Communication: Works across stakeholders and teams and communicates findings clearly.
- Adaptability: Thrives in a fastâpaced biotech environment.
Desirable: Experience in oncology, tissue fibrosis and immune microenvironment pathology.
Why us?
At Engitix, you'll be part of a missionâdriven biotech pioneering extracellular matrix biology to develop transformative therapies in fibrosis and oncology. This fixedâterm contract offers the chance to apply histology expertise to impactful discovery programmes, working alongside talented scientists in stateâofâtheâart laboratories at The Westworks, White City.
Join us and contribute to a mission that combines scientific excellence with the drive to bring new medicines to patients who need them most.
About Us
Engitix is a growing biotech company based in White City Place, West London. We are dedicated to developing better therapies for advanced fibrosis and solid tumours by leveraging our pioneering extracellular matrix (ECM) platform. Our platform allows the synthesis of realistic in vitro 3D models that serve as tools to transform our ability to identify new targets and biomarkers, determine mechanisms of action and more accurately predict the efficacy of therapeutic candidates.
Join us today in our mission to create a healthier future for patients with lifeâthreatening diseases such as fibrosis and cancer.
Seniority level: MidâSenior level
Employment type: Contract
Job function: Science and Research
Industries: Business Consulting and Services
Scientist/Senior Scientist - Histology and Target Expression (12 month FTC) in London employer: Engitix Therapeutics
Contact Detail:
Engitix Therapeutics Recruiting Team
StudySmarter Expert Advice đ¤Ť
We think this is how you could land Scientist/Senior Scientist - Histology and Target Expression (12 month FTC) in London
â¨Tip Number 1
Network like a pro! Reach out to your connections in the biotech field, especially those who work at Engitix or similar companies. A friendly chat can sometimes lead to insider info about job openings or even a referral.
â¨Tip Number 2
Prepare for interviews by brushing up on your histology and tissue-based techniques. Be ready to discuss your hands-on experience with IHC and immunofluorescence, as well as how you've contributed to drug discovery programmes in the past.
â¨Tip Number 3
Showcase your adaptability! In a fast-paced biotech environment, it's crucial to demonstrate how you've thrived under pressure. Share examples of how you've successfully navigated challenges in previous roles.
â¨Tip Number 4
Don't forget to apply through our website! Itâs the best way to ensure your application gets noticed. Plus, it shows you're genuinely interested in joining our mission at Engitix.
We think you need these skills to ace Scientist/Senior Scientist - Histology and Target Expression (12 month FTC) in London
Some tips for your application đŤĄ
Tailor Your CV: Make sure your CV highlights your relevant experience in histology and tissue-based studies. We want to see how your skills align with our mission at Engitix, so donât hold back on showcasing your hands-on expertise!
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why youâre passionate about our work in fibrosis and oncology. Let us know how your background makes you the perfect fit for this role.
Showcase Your Data Skills: Since we value high-quality data integrity, make sure to mention any experience you have with digital pathology and image analysis platforms. We love seeing candidates who can bring advanced tissue technologies to the table!
Apply Through Our Website: We encourage you to apply directly through our website. Itâs the best way for us to receive your application and ensures youâre considered for this exciting opportunity at Engitix!
How to prepare for a job interview at Engitix Therapeutics
â¨Know Your Histology Inside Out
Make sure you brush up on your histology, immunohistochemistry, and immunofluorescence techniques. Be ready to discuss specific experiments you've designed or executed in the past, and how they relate to the role at Engitix. This will show that youâre not just familiar with the concepts but have practical experience.
â¨Prepare for Data Discussion
Since you'll be analysing and presenting histological data, think about examples where your data influenced decision-making in previous roles. Be prepared to explain your thought process and how you ensured data integrity and quality in your work.
â¨Showcase Your Collaboration Skills
Engitix values teamwork, so come equipped with stories that highlight your ability to work across different teams. Think of instances where you collaborated with biologists or data scientists, and how your communication helped drive a project forward.
â¨Stay Adaptable and Enthusiastic
The biotech environment can be fast-paced and ever-changing. Share experiences that demonstrate your adaptability and enthusiasm for tackling new challenges. This will resonate well with Engitix's mission-driven culture and their focus on impactful science.
