Principal Scientist, Molecular Biology

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Site Name: UK – Hertfordshire – Stevenage
Posted Date: Mar 4 2025

We are seeking a highly motivated Scientist with hands-on expertise in genomics/molecular biology to join the Oncology Translational Research team within GSK Oncology TA. The successful candidate will work as part of a team that evaluates patient-derived tissues through cutting-edge cellular, genomic and molecular techniques, and partners with AI/ML and analytics experts to integrate data from these multimodal approaches to generate clinical insights. The goal of this is to improve cancer patient risk stratification, identify clinical biomarkers and predict future targeted and/or immuno-therapy susceptibilities.

In this role you will

• Create protocols and perform the sample processing for genomic experiments (e.g. RNAseq, WES, scRNAseq). These capabilities will be applied to ex vivo models and biobanked tumour tissues.
• Work closely with other leaders in the Oncology Translational Research team to ensure alignment and integration of cancer genomics with other functions.
• Actively consider and recommend internal vs external options for delivery of individual genomics approaches.
• Keep abreast of the latest research and technological advancements in genomics and molecular biology to ensure the team is using the most current and effective methods.
• Execute and deliver data of the project to a high quality and within defined timeframes.
• Offer technical expertise and support to other team members, helping them troubleshoot and optimize their experimental protocols. Solve technical issues operate as part of a cross-functional project team.
• Ensure proper storage, tracking, and documentation of samples used for genomics experiments.
• Collaborating with KCL scientists within the GSK-KCL Translational Oncology Research Hub, an exclusive research collaboration between GSK and the Comprehensive Cancer Centre at KCL.

Why you?

Basic Qualifications & Skills

We are looking for professionals with these required skills to achieve our goals:

• Strong background in developing and applying cutting-edge genomic technologies to study cancer biology
• Experience with functional genomic and molecular biology methods, including RNAseq and NGS approaches
• Strong understanding of cancer biology, including the molecular mechanisms underlying tumorigenesis and cancer progression
• Ability to communicate with team members from different backgrounds by training/discipline, as well as senior members of the GSK stakeholders/research partner units
• Ability to deliver high quality, consistent results in a timely fashion with a positive can-do and result oriented attitude

Preferred Qualifications & Skills

Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:

• PhD in Cancer Biology, Genomics, or related field, with extensive experience in cancer genomics
• A track record of scientific Publication
• Experience in collaboration with biopharma
• Excellent leadership and communication skills
• Strong strategic thinking and problem-solving skills, with the ability to navigate complex scientific and business challenges

Closing Date for Applications – 17th March 2025 (COB).

Please take a copy of the Job Description, as this will not be available post closure of the advert.

When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease. Science and technology are coming together in a way they never have before, and we have strong tech-enabled capabilities that allow us to build a deeper understanding of the patient, human biology and disease mechanisms, and transform medical discovery. We are revolutionising the way we do R&D. We’re uniting science, technology and talent to get ahead of disease together.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

As an Equal Opportunity Employer, we are open to all talent.

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