At a Glance
- Tasks: Develop innovative ocular disease models and conduct advanced bioassays.
- Company: Join a cutting-edge CRO focused on human-relevant drug discovery.
- Benefits: Opportunity to make a real impact in a dynamic lab environment.
- Other info: Be part of a growing team dedicated to reducing animal testing.
- Why this job: Combine hands-on lab work with scientific innovation and commercial growth.
- Qualifications: Experience with iPSC-derived systems and strong lab skills in bioassays.
The predicted salary is between 40000 - 50000 £ per year.
We are seeking an Ophthalmology Bioassay Senior Scientist to join a growing, innovative CRO environment focused on developing next-human-relevant disease models. This role sits at the forefront of moving drug discovery away from traditional animal models, with a strong emphasis on advanced in vitro systems, including iPSC-derived models and 3D organoids for ocular diseases. You will play a key role in building and developing capability in ophthalmology, contributing to both project delivery and the longer-term growth of this area of the business. This is an excellent opportunity for someone who enjoys combining hands-on lab work, scientific innovation, and commercial impact.
Responsibilities
- Ocular Model Development
- Develop and optimise human-relevant ocular disease models
- Design and implement iPSC-derived systems, including retinal and epithelial models
- Contribute to the development of complex 3D organoid and co-culture systems
- Assay Development & Delivery
- Design and execute bioassays relevant to ocular disease, including:
- Imaging and fluorescence-based assays
- Immunoassays
- Functional and translational assays
- Analyse and interpret experimental data and present findings clearly to stakeholders
- Molecular & Cell Biology
- Apply molecular biology techniques including:
- Gene knockdown approaches (e.g., siRNA, shRNA)
- Work with primary cells, cell lines, and stem-cell derived models
- Support development of increasingly complex and physiologically relevant systems
- Project Delivery & Growth
- Support delivery of CRO projects across drug discovery programmes
- Troubleshoot experimental challenges and drive continuous improvement
- Contribute to building and scaling ophthalmology capability, including future team growth
- Engage with clients and support scientific discussions where required
About You
You are a scientist with strong hands-on experience in advanced cellular models, particularly within ophthalmology or closely related disease areas. You’ll bring:
- Experience working with iPSC-derived systems and/or 3D organoid models (critical)
- Strong laboratory experience across bioassays, imaging, and molecular biology techniques
- Experience working with ocular models or strong transferable cell biology experience
- A proactive, problem-solving mindset with the ability to work independently
Desirable (but not essential)
- PhD in Ophthalmology, Cell Biology, Stem Cell Biology, or a related discipline
- Experience in a CRO or fast-paced applied research environment
- Exposure to replacing or reducing animal models with human-relevant systems
- Interest in helping build or grow a new scientific capability or team
If you’re excited by organoids, stem cell models, and reducing reliance on animal testing, this role will give you the platform to make a real impact. Apply now by attaching your CV in Word, or contact Paige Keenan for further information about this new role.
Ophthalmology Bioassay Senior Scientist in Nottingham employer: Energy Jobline ZR
Join a pioneering CRO in Nottingham that champions innovation and scientific advancement in ophthalmology. With a strong focus on employee growth, you will have the opportunity to engage in cutting-edge research while contributing to meaningful projects that reduce reliance on traditional animal models. Our collaborative work culture fosters creativity and encourages professional development, making it an ideal environment for passionate scientists eager to make a significant impact in drug discovery.
StudySmarter Expert Advice🤫
We think this is how you could land Ophthalmology Bioassay Senior Scientist in Nottingham
✨Tip Number 1
Network like a pro! Reach out to professionals in the ophthalmology and bioassay fields on LinkedIn. Join relevant groups, attend webinars, and don’t be shy about asking for informational interviews. We all know that sometimes it’s not just what you know, but who you know!
✨Tip Number 2
Prepare for those interviews! Research the company and its projects, especially their work with iPSC-derived systems and 3D organoids. We want you to show your passion for innovative drug discovery and how you can contribute to their growth.
✨Tip Number 3
Showcase your hands-on experience! During interviews, share specific examples of your lab work, especially any projects involving ocular models or advanced cellular techniques. We love hearing about real-world applications of your skills!
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets seen by the right people. Plus, we’re always looking for passionate individuals who want to make a difference in the field of ophthalmology.
We think you need these skills to ace Ophthalmology Bioassay Senior Scientist in Nottingham
Some tips for your application 🫡
Tailor Your CV:Make sure your CV highlights your experience with iPSC-derived systems and 3D organoid models. We want to see how your skills align with our focus on innovative ocular disease models, so don’t hold back!
Showcase Your Lab Skills:In your application, emphasise your hands-on lab experience, especially with bioassays and molecular biology techniques. We’re looking for someone who can hit the ground running, so let us know what you’ve done!
Be Clear and Concise:When writing your cover letter, keep it straightforward and to the point. We appreciate clarity, so make sure you communicate your passion for reducing reliance on animal testing and your interest in building new scientific capabilities.
Apply Through Our Website:Don’t forget to apply through our website! It’s the best way for us to receive your application and ensures you’re considered for this exciting opportunity. We can’t wait to hear from you!
How to prepare for a job interview at Energy Jobline ZR
✨Know Your Models
Make sure you brush up on your knowledge of iPSC-derived systems and 3D organoid models. Be ready to discuss how you've used these in your previous work, as well as any innovative approaches you've taken. This will show that you're not just familiar with the concepts but can also apply them effectively.
✨Showcase Your Problem-Solving Skills
Prepare examples of challenges you've faced in the lab and how you overcame them. Highlight your proactive mindset and ability to troubleshoot experimental issues. This is crucial for a role that emphasises continuous improvement and project delivery.
✨Communicate Clearly
Practice presenting your findings in a clear and concise manner. You might be asked to explain complex data or methodologies to stakeholders who may not have a scientific background. Being able to communicate effectively will set you apart from other candidates.
✨Engage with the CRO Environment
Familiarise yourself with the specific challenges and opportunities within a Contract Research Organisation (CRO). Show enthusiasm for contributing to project delivery and growth in ophthalmology. This demonstrates that you understand the business side of science and are eager to make an impact.
