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- Tasks: Engineer enzymes using cutting-edge AI technology and collaborate with a multidisciplinary team.
- Company: Join Imperagen, an innovative AI-powered enzyme engineering company in Manchester.
- Benefits: Competitive salary, equity options, and the chance to work on groundbreaking projects.
- Other info: Exciting opportunity for career growth in a dynamic lab environment.
- Why this job: Be part of a pioneering team shaping the future of biocatalysis and autonomous experimentation.
- Qualifications: PhD in chemistry or biochemistry, with experience in enzyme assays and analytical techniques.
The predicted salary is between 40000 - 50000 £ per year.
About Imperagen
Imperagen is building an AI-powered enzyme engineering company focused on biocatalysis. Our ambition is to create a proprietary AI platform that connects computational design, experimental validation, and real-world commercial outcomes in a system that gets smarter over time. We believe the future of biocatalysis will be shaped by autonomous closed-loop experimentation, where AI, software, and lab workflows work together to accelerate discovery, improve decision quality, and compound learning across programs.
The Role
We are hiring a biocatalysis and analytical development expert to join our team in Manchester. You will work closely within our multidisciplinary team delivering enzyme engineering programs and contributing to the development of our closed-loop enzyme technology platform.
Responsibilities
- This is a laboratory-based role, where the primary task will be to use Imperagen’s closed-loop platform to engineer enzymes in commercial programs.
- You will have responsibility for maintaining the analytical equipment (HPLC, UPLC and LC-MS).
- Knowledge of biocatalysis and enzyme chemistry is also highly desirable.
- You will be required to:
- Establish and optimise analytical and screening methods using UV/Vis, fluorescence, HPLC, and MS.
- Provide expertise in analytical methodologies and techniques to the team, especially relative to high throughput assay development and maintenance of the equipment.
- Provide expertise in biocatalysis and biotransformations reactions to the team.
- Design and perform molecular biology experiments including PCR and site-directed mutagenesis.
- Express recombinant proteins (e.g. in E. coli) and carry out purification protocols.
- Develop and run enzyme screening and characterisation assays.
- Analyse, document, and communicate experimental data.
- Collaborate with computational scientists to integrate experimental and in silico workflows.
- Contribute to development of automated and scalable laboratory systems and processes.
Required Experience and Qualifications
- PhD in chemistry, biochemistry or a related field.
- Experience with enzyme assays and analytical techniques (HPLC, UPLC, LC-MS, GC).
- Deep understanding of biocatalysis and biotransformation reaction chemistry.
- Strong understanding of enzyme engineering and directed evolution.
- Experience with microbial culture and recombinant protein expression.
- Proficiency in molecular biology techniques.
- Strong teamwork and communication skills.
- Postdoctoral or industry experience in enzyme engineering.
- Knowledge of enzyme mechanisms, kinetics, or structural biology.
- Experience with lab automation or high-throughput workflows.
- Familiarity with computational biology tools or data systems.
Eligibility to work in the UK
Candidates must have the legal right to work in the UK. Please note that Imperagen is not able to provide visa or work permit sponsorship for this role.
Compensation
Imperagen offers a competitive salary plus equity.
Why Join Imperagen
This is a rare opportunity to build something foundational. You will join a skilled and motivated team, working on real-world systems where software, models, and experimental science come together.
Closing date: Wednesday 13th May
Relevant candidates should reach out to us on: Biocatalysis_Analytical_Development@imperagen.com
Biocatalysis & Analytical Development Scientist in Manchester employer: Energy Jobline ZR
Contact Detail:
Energy Jobline ZR Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Biocatalysis & Analytical Development Scientist in Manchester
✨Tip Number 1
Network like a pro! Reach out to professionals in the biocatalysis and analytical development field on LinkedIn. Join relevant groups, participate in discussions, and don’t hesitate to ask for informational interviews. We all know that sometimes it’s not just what you know, but who you know!
✨Tip Number 2
Prepare for your interview by brushing up on your technical knowledge. Make sure you can discuss enzyme engineering, analytical techniques, and your past experiences confidently. We recommend practising common interview questions with a friend or even in front of the mirror to nail that delivery!
✨Tip Number 3
Showcase your passion for biocatalysis! During interviews, share your enthusiasm for the field and any personal projects or research you've done. We want to see that spark in you, so let your excitement shine through!
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets seen by the right people. Plus, it shows you’re genuinely interested in joining our team at Imperagen. Let’s make this happen together!
We think you need these skills to ace Biocatalysis & Analytical Development Scientist in Manchester
Some tips for your application 🫡
Tailor Your CV: Make sure your CV is tailored to the role of Biocatalysis & Analytical Development Scientist. Highlight your relevant experience with enzyme engineering, analytical techniques, and any specific projects that align with our AI-powered platform.
Craft a Compelling Cover Letter: Your cover letter should tell us why you're passionate about biocatalysis and how your skills can contribute to our team. Be sure to mention any unique experiences or insights you have that relate to our mission at Imperagen.
Showcase Your Teamwork Skills: Since this role involves collaboration with a multidisciplinary team, emphasise your teamwork and communication skills in your application. Share examples of how you've successfully worked with others in past projects.
Apply Through Our Website: We encourage you to apply through our website for a smoother application process. It helps us keep track of your application and ensures you don’t miss out on any important updates from us!
How to prepare for a job interview at Energy Jobline ZR
✨Know Your Biocatalysis Basics
Make sure you brush up on your biocatalysis and enzyme chemistry knowledge. Be ready to discuss specific techniques you've used, like HPLC or LC-MS, and how they relate to the role. This shows you're not just familiar with the theory but have practical experience too.
✨Showcase Your Analytical Skills
Prepare to talk about your experience with analytical methodologies. Think of examples where you've established or optimised screening methods. Being able to articulate your approach to high-throughput assay development will impress the interviewers.
✨Collaboration is Key
Since this role involves working closely with a multidisciplinary team, be ready to share examples of successful collaborations. Highlight how you've communicated complex data or worked with computational scientists in the past to integrate workflows.
✨Ask Insightful Questions
Prepare some thoughtful questions about Imperagen's closed-loop platform and their future projects. This not only shows your interest in the company but also demonstrates your proactive mindset and eagerness to contribute to their innovative work.