At a Glance
- Tasks: Lead the design and development of innovative clinical data applications using cutting-edge technologies.
- Company: Join eClinical Solutions, a leader in transforming healthcare through technology.
- Benefits: Competitive salary, remote work options, and a culture that values diversity and inclusion.
- Other info: Be part of a team that celebrates innovation and personal growth.
- Why this job: Make a real-world impact on healthcare while advancing your career in a fast-growing company.
- Qualifications: 10+ years in software development with expertise in C#, .NET, and full-stack web applications.
The predicted salary is between 63000 - 77000 £ per year.
About eClinical Solutions eClinical Solutions is transforming clinical development with elluminate®, our Clinical Data Cloud, helping life sciences organizations unify, analyze, and unlock the value of their data faster than ever before. By combining a modern cloud platform with expert data services, we empower smarter decisions across the clinical trial lifecycle—accelerating innovation that ultimately improves patient outcomes. Our engineering teams build enterprise-grade, revenue-generating products at the intersection of cloud, data, analytics, and emerging AI technologies. If you’re excited about building sophisticated software that makes a real-world impact on healthcare, this is the place to do it.
You will make an impact: As a Principal Full Stack Software Engineer, you will be a technical leader within the elluminate Product Development team. You’ll help design and build the core services and user experiences of a next-generation clinical data and analytics platform—while influencing architecture, engineering standards, and technical direction. This role is ideal for an experienced engineer who enjoys hands‑on development, mentoring others, and bringing modern capabilities—including AI‑assisted and agentic workflows—into production‑grade systems.
Your day to day:
- Design, develop, test, and deploy scalable, secure, and highly interactive web applications
- Own and evolve core platform modules, from concept through release and support
- Influence application and system architecture with a focus on performance, reliability, security, and maintainability
- Lead by example through clean, well‑tested code, thoughtful design reviews, and pragmatic technical decisions
- Collaborate closely with Product Management, QA, and other engineers throughout the SDLC
- Provide technical mentorship and guidance to other engineers on the team
- Diagnose and resolve complex production issues across distributed systems
- Ensure solutions meet eClinical Solutions quality standards and applicable industry regulations
- Contribute to technical documentation including design specs, acceptance criteria, and release notes
AI & Modern Engineering Focus We’re actively incorporating AI‑powered capabilities into our platform, and you’ll help shape how this is done responsibly and effectively in an enterprise environment. This includes:
- Integrating LLMs and AI services into .NET- and Python‑based systems
- Designing and implementing AI‑assisted workflows, copilots, or intelligent automation features
- Working with agentic AI patterns (e.g., task orchestration, tool‑using agents, workflow automation)
- Applying prompt engineering, evaluation techniques, and guardrails to ensure reliability and compliance
- Collaborating with data and platform teams to operationalize AI—not just prototype it
Deep ML expertise is not required—we’re looking for strong engineers who understand how to apply AI capabilities in real products.
Here is what we are looking for in this role. Qualifications:
- Bachelor’s or Master’s degree in Computer Science or equivalent practical experience
- 10+ years in software design and development using the Microsoft technology stack preferred
- Expert‑level proficiency in C#, .NET, and ASP.NET (MVC/Web APIs)
- Strong experience building full‑stack web applications (Angular, TypeScript, HTML, CSS)
- Solid understanding of software design principles, patterns, and best practices
- Experience across the full Software Development Lifecycle (Agile preferred)
- Proven ability to work independently while collaborating effectively in a fast‑paced environment
- Excellent communication, documentation, and technical leadership skills
AI & Platform Experience
- Hands‑on experience integrating LLM‑based services (e.g., OpenAI, Azure OpenAI, or similar) into applications
- Experience using Python and/or .NET alongside AI/LLM workflows
- Familiarity with agent‑based or workflow‑driven AI architectures is a strong plus
- Understanding of secure and responsible AI usage in enterprise systems
Nice to Have
- Strong SQL expertise (Microsoft SQL Server preferred), including performance tuning
- Experience with microservices, distributed systems, and cloud platforms (AWS preferred)
- Secure development experience, including awareness of common vulnerabilities and mitigations
- Experience with clinical trial data, life sciences, or regulated SaaS environments
- Experience building data visualizations or analytics‑driven user experiences
Accelerate your skills and career within a fast-growing company while impacting the future of healthcare. We have shared our story, now we look forward to learning yours!
eClinical is a winner of the 2025 Top Workplaces USA Award for Remote Work! We have also received numerous Top Workplaces Culture Excellence Awards celebrating our exceptional company vision, values, and work‑life balance.
eClinical Solutions is a people first organization. Our inclusive culture values the contribution that diversity brings to our business. We celebrate individual experiences that connect us and that inspire innovation in our community. Our team seeks out opportunities to learn, grow and continuously improve. Bring your authentic self, you are welcome here! We are proud to be an equal opportunity employer that values diversity. Our management team is committed to the principle that employment decisions are based on qualifications, merit, culture fit and business need.
Principal Software Engineer in Mansfield employer: eClinical Solutions
eClinical Solutions is an exceptional employer, offering a dynamic work environment where innovation meets impact in the healthcare sector. With a strong focus on employee growth and a commitment to diversity, we provide opportunities for professional development while fostering a culture that values collaboration and inclusivity. Our recognition as a Top Workplace for Remote Work underscores our dedication to work-life balance and employee satisfaction, making it an ideal place for passionate engineers to thrive.
StudySmarter Expert Advice🤫
We think this is how you could land Principal Software Engineer in Mansfield
✨Join Local Tech Meetups
Get out there and mingle with fellow developers by joining local tech meetups. It’s a fantastic way to meet people who might be working at eClinical Solutions or know someone who does. Plus, you can pick up some trendy tech skills and trends while you're at it!
✨Contribute to Open Source Projects
Show off your coding chops by jumping into open-source projects. Not only does this give you practical experience, but it also gets you noticed in the dev community. You'll create a killer portfolio that speaks volumes about your skills to eClinical Solutions.
✨Tap into Online Developer Communities
Don’t underestimate the power of online developer communities like GitHub, Stack Overflow, and even Reddit. Participate in discussions, share your projects, and build your visibility. We can often find opportunities through these channels that can lead to a full-time gig at companies like eClinical Solutions.
✨Explore Job Boards Specifically for Tech Roles
Keep your eyes peeled on job boards that focus on tech roles. Sites like TechCareers or Stack Overflow Jobs can often have listings for companies like eClinical Solutions that might not show up on broader job sites. Make it a habit to check these regularly, and don’t hesitate to apply directly through our website!
We think you need these skills to ace Principal Software Engineer in Mansfield
Some tips for your application 🫡
Show off your coding skills:When applying for a software engineering role, it's super important to showcase your coding skills. Make sure your CV includes your tech stack, any relevant programming languages you’re comfortable with, and examples of projects you've worked on. If you have a GitHub profile, link it up! We love to see code in action.
Tailor your portfolio:For a full-time role, we’d expect to see some solid examples of your work in your portfolio. Make sure to include at least two or three projects that highlight your problem-solving skills and your ability to work with different technologies. Focus on the projects that are most relevant to the position at eClinical Solutions.
Craft a killer cover letter:Your cover letter is your chance to stand out—make it personal! Explain why you want to work at eClinical Solutions and how your skills align with the role. Show us your passion for software development. We dig enthusiastic candidates who understand the value of collaboration and continuous learning!
Be clear and concise:When it comes to writing your CV and cover letter, clarity is key. Avoid jargon that could confuse us and stick to simple, direct language. Highlight your achievements with quantifiable results where possible, and keep everything easy to read. A well-organised application goes a long way!
How to prepare for a job interview at eClinical Solutions
✨Brush Up on Your Coding Skills
For a full-time software engineering role, it's crucial that we stay sharp with our coding abilities. Expect technical questions that might involve solving problems on the spot or discussing algorithms. Practise on platforms like LeetCode or HackerRank to get comfortable with the types of questions that often come up.
✨Know Your Tools and Frameworks
Make sure we’re well-acquainted with the tools and technologies listed in the job description. Familiarise ourselves with any specific frameworks or programming languages mentioned. If eClinical Solutions uses React or Node.js, for instance, be ready to discuss how we’ve used them in previous projects or coursework.
✨Showcase Your Projects
Bring along a portfolio that highlights our best work. This could be code samples, GitHub repositories, or any side projects we’ve built. Make sure we can talk through our thought process for each project, especially the challenges we faced and how we solved them—this shows our problem-solving skills in action.
✨Prepare for Behavioural Questions
While technical skills are key, full-time positions also require cultural fit. Be ready to discuss our previous experiences and how we handle teamwork, conflict, and deadlines. Brush up on the STAR method—Situation, Task, Action, Result—to clearly articulate our past experiences when discussing how we've contributed to a team.
