At a Glance
- Tasks: Lead and manage multi-centre cancer clinical trials, ensuring compliance and quality assurance.
- Company: Join the Sheffield Clinical Trials Research Unit, a leader in oncology research.
- Benefits: Enjoy 41 days annual leave, flexible working, and a generous pension scheme.
- Other info: Dynamic role with opportunities for mentorship and professional growth.
- Why this job: Make a real impact in cancer research while developing your career in a supportive environment.
- Qualifications: Postgraduate qualification and experience in managing large oncology trials required.
The predicted salary is between 48822 - 65509 £ per year.
We offer a fantastic range of benefits including a highly competitive annual leave entitlement (with the ability to purchase more), a generous pensions scheme, flexible working opportunities, a commitment to your development and wellbeing, a wide range of retail discounts, and much more. Find out more about our benefits and join us to become part of something special.
Overview
A position has arisen for a Senior Trial Manager, equivalent to Senior Research Fellow (Grade 9) or Research Fellow (Grade 8), based in the Sheffield Clinical Trials Research Unit (CTRU). Sheffield CTRU has received substantial infrastructure funding to grow and diversify its portfolio of multi‑centre cancer clinical trials. The post holder will be responsible for trial design, grant development, and submission, as well as oversight of Quality Assurance and senior‑level study implementation, with a specific focus on oncology‑based CTIMPs as part of the Sheffield Oncology Clinical Trials Infrastructure Programme (SOCTIP). You will work closely with the CTRU Academic Lead for Oncology, CTRU staff and Chief Investigators to secure research funding and ensure that studies under your supervision are implemented in accordance with randomised controlled trial scientific principles, the study protocols, and regulatory standards.
You will provide oversight of all CTRU input into the specialist oncology studies within your portfolio, ensuring that all services provided by the Unit are compliant with professional, national, and international regulatory frameworks. Whilst the post is funded fixed term until March 2031, if successful, it is envisaged that the position will be income generating and so funded on an ongoing basis beyond this.
Main duties and responsibilities
- Portfolio Management: Support the CTRU Director and Academic Lead for Oncology in the strategic delivery of the Sheffield Oncology Clinical Trials Infrastructure Programme (SOCTIP).
- Trial Delivery: Responsible for overseeing the set‑up, coordination, and delivery of large multi‑site clinical trials, including protocol development, obtaining regulatory approvals (IRAS/MHRA), and site initiation.
- Leadership (G9): Lead the development of a specialist oncology research portfolio, taking a primary role in designing studies and securing large research grants.
- Support & Advice (G8): Provide expert advice and support to researchers developing new funding proposals, specifically regarding trial design, resource costing, drug procurement and project management timelines.
- Regulatory & Quality Assurance: Oversee Quality Assurance processes and ensure compliance with the Medicines for Human Use (Clinical Trials) Regulations 2004, GCP, and data protection requirements.
- Staff Supervision: Supervise Trial Managers and study‑specific staff, providing mentorship and guidance on trial implementation.
- Research Output (G9): Lead the preparation of papers for high‑impact oncology and academic journals and present findings at international conferences.
- Research Output (G8): Contribute and lead to academic papers and the dissemination of research findings through reports and publications.
Person Specification
Our diverse community of staff and students recognises the unique abilities, backgrounds, and beliefs of all. We foster a culture where everyone feels they belong and is respected. Even if your past experience doesn't match perfectly with this role's criteria, your contribution is valuable, and we encourage you to apply. Please ensure that you reference the application criteria in the application statement when you apply.
Essential Qualifications
- Postgraduate qualification or equivalent experience in a relevant health‑related or methodological area.
Trial Experience
- Experience in trial set‑up and delivery for large, multi‑centre CTIMPs.
- Proven track record of managing large, multi‑centre oncology CTIMPs from set‑up to close‑out.
Oncology Expertise
- Extensive experience and deep understanding of cancer‑specific trial complexities.
- Research experience within the oncology field (desirable).
CTIMP Experience
- Experience coordinating Clinical Trials of Investigative Medicinal Products (CTIMPs).
- Extensive experience working on complex oncology CTIMPs and oncology pharmacovigilance.
Income Generation
- Experience supporting the writing of grant applications and coordinating expertise for proposals.
- Proven track record of successfully securing major research grants (e.g., NIHR, CRUK, MRC).
Publications
- Experience in substantial contribution to papers of clinical trials in academic journals, including some as first author.
- Strong track record of high‑quality, peer‑reviewed research papers of clinical trials in high‑impact oncology journals.
Leadership
- Experience in supervising/coordinating study staff and motivating a team.
- Experience in supervising Trial Managers and mentoring early‑career researchers.
Salary and Benefits
Grade 8: £48,822–£65,509 per annum. Grade 9: £61,759–£80,254 per annum. Full‑time (Hybrid). Fixed term until 31 March 2031. Benefits include: 41 days annual leave (pro‑rata) with the ability to purchase more, flexible working opportunities, generous pension scheme, a wide range of staff discounts and rewards, inclusive staff networks, recognition awards, and a commitment to development through learning and mentoring schemes.
Next steps in the recruitment process
It is anticipated that the selection process will take place in September. This will consist of a 10‑minute presentation and subsequent interview. If you need any support, equipment or adjustments to enable you to participate in any element of the recruitment process you can contact dph‑section‑ Disability support. We are a Disability Confident Employer. If you have a disability and meet the essential criteria for this job you will be invited to take part in the next stage of the selection process.
Contact
For informal enquiries about this job contact Prof Matt Hammond, Director of the Sheffield Clinical Trials Research Unit.
Closing Date: 03 Aug 2026
Senior Trial Manager Research Fellow or Senior Research Fellow in Sheffield employer: Dunhillmedical
The University of Sheffield is an exceptional employer, offering a vibrant academic environment where innovation in teaching and research thrives. With a strong commitment to employee development, you will have access to numerous growth opportunities, collaborative projects, and a supportive community that values inclusivity and excellence in education. Located in a dynamic city known for its rich culture and student-friendly atmosphere, this role as a Lecturer in Business Analytics promises not only professional fulfilment but also a rewarding lifestyle.
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