Director, Precision Medicine (Cell Medicine)

We are seeking to hire a Precision Medicine Scientific Lead to oversee the development and execution of biomarker strategies for novel cell therapies, cell transfer conditioning agents and combinations with bispecific antibodies across multiple disease areas (Oncology and Immunology). In this highly matrixed role, they will design, develop, communicate across levels and operationally implement clinical biomarker strategies to support selective programs in early and late stage drug development. Clinical biomarker assays include pharmacokinetic assays, mechanism of action, patient stratification assays and pharmacodynamic assays.

The candidate will collaborate with teams internal to RCM and more broadly Regeneron or with contract research organizations to develop and implement clinical biomarker assays. As a Director, a typical day may include the following:

• Program-level Precision Medicine lead that develops and implements the strategic vision for pharmacokinetic, pharmacodynamic, and exploratory biomarkers for clinical studies enabling indication and/or patient selection, early indication of biological activity, and to identify potential novel combinations.
• Strong collaboration with Biomarker and clinical operation teams to implement specific biomarker and exploratory sample collection and analyses in all relevant clinical studies in selected programs.
• Key individual contributor and precision medicine representative to development and Cell therapy characterization teams with a remit to integrate, influence and deliver biomarker strategies from initial concept to execution, data delivery and results interpretation.
• Collaborate with internal Regeneron laboratories and groups (e.g. BioAnalytical, Clinical Pharmacology, Molecular Profiling, CDX, Discovery Research, Analytical Innovations, DMSQ etc.) to develop plan for validation and application of assays in the clinic.
• Accountability for ensuring complex clinical assays used in programs are fit‑for‑purpose (whether developed and validated internally or externally).
• Collaborate with Discovery Research and product development teams to facilitate appropriate incorporation of Precision Medicine biomarker strategies for molecules in discovery phases (leading to candidate molecule selection) through to the clinic.
• Represent Regeneron externally through collaborations and/or presentations.
• Contribute to Clinical Protocol, schedule of Assessments, clinical study reports, technical reports, data agreements, scientific publications and make recommendations to development teams and management.

This role may be for you if:

• The ability to drive, manage, complete and deliver results for complex multi‑functional projects.
• Excellent communication and presentation skills and high emotional intelligence, organizational skills and effective team skills.

To be considered for this role, you must have a PhD and 10+ years of experience participating effectively on cross‑disciplinary teams in pharmaceutical or biotech industry. Experience in clinical assay development, validation and implementation with strong experience in Immunology is preferred.

We have an inclusive culture that provides comprehensive benefits, which vary by location. In the U.S., benefits may include health and wellness programs (including medical, dental, vision, life, and disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees at all levels.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations.

The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company’s business.

Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.