Research Associate in Digital Twins for Healthcare in Sheffield

The University of Sheffield is a remarkable place to work. Our people are at the heart of everything we do. Their diverse backgrounds, abilities and beliefs make Sheffield a world-class university.

This is an exciting opportunity for a Research Associate from an engineering (systems, control or signal processing) or computer science (machine learning or data-driven modelling) background to support a major project at the intersection of systems engineering and healthcare delivery. You will work with a highly interdisciplinary research team and with our clinical and health data partners to ensure that systems engineering processes are applied to the reshaping of healthcare services. You will identify data analytics functions and digital twin requirements and develop software solutions integrating these components. You will have mathematical, modelling and computational skills, and be able to apply these in a dynamic and interdisciplinary research environment.

RESHAPE-CARE (re-engineering services for health, maximising person-centred care) is a research and innovation programme to transform care for people with multiple long-term conditions. It represents a partnership between systems engineers, healthcare researchers, health data experts and health service providers. It seeks to integrate the human (ensuring person-centred preferences about care) with the technological (digital twin computer models of health systems). The process of designing and implementing changes within services (general practices and community diagnostic centres) will follow systems engineering principles: an important part of this mixed methods researcher role is to participate in that process and also reflect and report on it. The project is underpinned by a strong commitment to Patient and Public Involvement and Engagement (PPIE) including people from underserved and under-represented communities.

Main duties and responsibilities:

• Work with systems engineers and the model-based systems engineering model of the digital twin to build data-driven models of patients with multiple long-term conditions to the requirements.
• Work with relevant health datasets to pre-process time-series and other data to deal with missing information, synchronisation and any feature extraction to enable data-driven models to be built.
• Develop static and dynamic data-driven models using patient test and treatment data of multiple long term conditions patients using synthetic and real datasets.
• Contribute to the development of digital twins and data analytics functions working across data platforms and operating environments, coordinating with project partners and the research team.
• Conduct a comprehensive literature review to highlight state-of-the-art research in digital twins and its applications in healthcare.
• Prepare high quality papers for journals/presentations at technical level at national/international conferences and seminars for dissemination, and at a lay-person level to inform findings to multiple stakeholders.
• Report to supervisors and the wider project team on a regular basis about your research plan and results to discuss / agree any changes to the plan.
• Deliver project objectives assigned to your work package in a timely fashion, and coordinate with other work packages to ensure the solutions are integrated for the success of the whole project.
• Produce documentation of software, models and digital twin implementations and follow appropriate handover protocols.
• Plan research effectively by continuously monitoring results; the unpredictability of research means that daily planning needs to accommodate new developments.
• Carry out other duties, commensurate with the grade and remit of the post.

As a Research Associate in Digital Twins for Healthcare, you will be responsible for working with the lead investigators to deliver the patient and population digital twins. This will involve working with stakeholders (public and services) and academics from engineering, data science and health. The engineering focus of RESHAPE-CARE will involve you working with relevant health datasets and services for diabetes and breathlessness as part of the management of people with multiple long-term conditions, and developing digital twins based solutions.

You will work, within an agile management framework, on a work package dedicated to the digital twins development. It will have a work-package or task-related team comprising investigators, researcher colleagues and experts by lived experience. You will also be a full member of the wider RESHAPE-CARE research team and be expected to share your work and its findings across the work packages. This means you will have to work with people from different backgrounds and academic disciplines. You will have project management and secretarial support from members of our professional services team.

You will use your data-driven modelling skills to develop the digital twins by working with the project partners. Experience of working with heterogeneous and complex data and/or health data would be valuable. You will apply software engineering skills to the development of data-driven models and digital twin based software solutions and deploy them as services. You will be responsible for producing software documentation and technical reports, as well as regular reports of your work in formats that are accessible to the team, including those from different disciplines.

You will be based in the School of Electrical and Electronic Engineering and work closely with colleagues in School of Health and Related Research (the buildings are only a short distance from each other). You will be required to visit the project partners and healthcare providers (GP practices and diagnostic centres in South Yorkshire, Manchester).

Our diverse community of staff and students recognises the unique abilities, backgrounds, and beliefs of all. We foster a culture where everyone feels they belong and is respected. Even if your past experience doesn't match perfectly with this role's criteria, your contribution is valuable, and we encourage you to apply.

Criteria:

• A PhD, or close to completion (or equivalent experience) in engineering (systems, control or signal processing), computer science (machine learning or data-driven modelling) or a related discipline.
• Demonstrable experience of data-driven modelling.
• Demonstrable knowledge of modelling dynamical systems from time-series data.
• Demonstrable ability to work with large and complex datasets.
• Demonstrable understanding/experience of working with health data.
• Demonstrable ability to work flexibly across data platforms and operating environments.
• Demonstrable experience of developing software in Matlab, C++ or Python.
• Demonstrable writing skills including both academic papers and reports for other internal and external purposes.
• Excellent communication skills including managing meetings, making presentations and effective 1:1 communication.
• Demonstrable ability to work effectively with people from different disciplines.
• Demonstrable ability to work independently, plan own workload and prioritise conflicting deadlines.
• Demonstrable ability to apply creative approaches to solving complex technical problems.

Further Information:

• Grade: 7
• Salary: £38,784 - £41,064
• Work arrangement: Full time (100% FTE, 35 hours per week)
• Duration: 41 months with an end date no later than 31 January 2030
• Line manager: Professor Visakan Kadirkamanathan

Closing Date: 30/08/2026