At a Glance
- Tasks: Lead a team in cutting-edge cryo-electron microscopy research and development.
- Company: Join Diamond Light Source, a world-leading scientific facility driving innovation.
- Benefits: Enjoy 26 days leave, flexible hours, and a fantastic pension scheme.
- Other info: Collaborate with diverse talents in a dynamic, supportive environment.
- Why this job: Make a real impact in life sciences with state-of-the-art technology.
- Qualifications: PhD or equivalent experience in cryoEM methods and structural biology.
The predicted salary is between 36000 - 60000 £ per year.
Overview
Diamond Light Source is one of the world’s most advanced scientific facilities. We’re home to the UK’s synchrotron light source, producing beams of light 10 billion times brighter than the sun. Probing the structure and composition of matter, our work drives innovation in everything from vaccines to nanotech.
The electron Bio-Imaging Centre (eBIC) at Diamond is the UK National Centre for cryo-electron microscopy in the life sciences. eBIC provides scientists with state-of-the-art instruments and expertise in the field of cryo-electron imaging, for single particle analysis, tomography, and electron diffraction.
About the Role
We now have an excellent opportunity at group-leader level for a Principal EM Scientist to underpin and further develop eBIC as a leading centre for cryoEM.
eBIC together with B24, a full-field cryo X-ray transmission microscopy beamline, makeup the Biological Cryo-Imaging group at Diamond, which combined with the capabilities of the physical science Imaging and Microscopy group provide an extraordinarily strong platform for using electrons, X-rays and visible light to image a diverse range of samples across a range of length and time scales.
As Principal EM Scientist you will lead a small team of scientists to establish a competitive research programme which exploits the capabilities of eBIC and Diamond in general and contribute to the development and operation of eBICs rapidly growing international user programme.
To facilitate establishing your research programme, funding for a post-doctoral research fellow is likely to be available, subject to a suitable case being made, as well as the opportunity for PhD studentships within Diamond\'s PhD programme. You will have access to state-of-the-art laboratories for structural and cellular biology embedded at eBIC and within the Research Complex at Harwell to pursue your research. We also expect candidates to apply for external grant funding through national and international funding agencies to take full advantage of the stimulating and exciting research environment at Diamond.
Instrumentation and software development is facilitated by dedicated support from Diamond’s computing, engineering and scientific software groups as well as partnerships with CCP-EM and the Rosalind Franklin Institute amongst others.
About You
Suitable candidates will hold an appropriate first degree along with a relevant MSc or PhD or demonstrate significant equivalent experience.
You will demonstrate expertise and a proven track record in cryoEM methods. A strong background in in situ structural biology, particularly cryoFIB/SEM, cryo-electron tomography and sub-tomogram averaging is highly desirable.
You will also have substantial experience with structural and cellular biology techniques, as well as proficiency in Windows, Linux, and Unix environments.
You will demonstrate strong interpersonal, communication and presentation skills, so as to interact effectively with staff and facility users at all levels.
Benefits
Diamond offers an exceptional benefits package to support staff in achieving a positive work/life balance. This includes 26 days annual leave plus Christmas closure, public holidays, 2 annual volunteering days and flexible working hours. We also offer an excellent defined benefit pension scheme. Staff also have access to a range of amenities on site including a nursery, cafes, a restaurant and sports and leisure facilities. A relocation allowance may also be available where applicable.
This role qualifies for a non-pensionable allowance of £3,500 per annum.
To Apply
Applicants are required to outline their suitability for this role via the online application process and should include a summary of current and future research plans (max 3 pages).
Diamond is a thriving international organization, attracting a diverse range of talented individuals from around the world. Our staff currently comprises 56 nationalities and we welcome applications from everyone interested in joining us.
The closing date for applications is 5th October 2025
Principal Electron Microscopy Scientist – eBIC employer: Diamond Light Source
At Diamond Light Source, we pride ourselves on being a leading employer in the scientific community, offering an exceptional work culture that fosters innovation and collaboration. Our employees benefit from a comprehensive package that includes generous annual leave, flexible working hours, and access to state-of-the-art facilities, all while contributing to groundbreaking research in cryo-electron microscopy. With ample opportunities for professional growth, including funding for post-doctoral research and PhD studentships, Diamond is committed to supporting your career development in a vibrant and diverse environment.
StudySmarter Expert Advice🤫
We think this is how you could land Principal Electron Microscopy Scientist – eBIC
✨Tip Number 1
Network like a pro! Reach out to current employees at Diamond Light Source on LinkedIn or attend relevant conferences. A friendly chat can sometimes lead to insider info about the role and even a referral!
✨Tip Number 2
Prepare for the interview by diving deep into eBIC's recent projects and publications. Show us you’re not just interested in the role, but that you’re genuinely excited about what we do and how you can contribute.
✨Tip Number 3
Practice your presentation skills! As a Principal EM Scientist, you'll need to communicate complex ideas clearly. Consider doing mock presentations with friends or colleagues to get comfortable.
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets seen. Plus, it shows us you’re serious about joining the Diamond team.
We think you need these skills to ace Principal Electron Microscopy Scientist – eBIC
Some tips for your application 🫡
Show Your Passion:When writing your application, let your enthusiasm for cryo-electron microscopy shine through! We want to see how excited you are about the role and how your background aligns with our mission at eBIC.
Tailor Your Research Plans:Make sure to include a summary of your current and future research plans that specifically relates to the work we do at eBIC. This is your chance to show us how you can contribute to our cutting-edge projects!
Be Clear and Concise:Keep your application clear and to the point. We appreciate well-structured documents that are easy to read. Remember, you have a maximum of 3 pages, so make every word count!
Apply Through Our Website:Don’t forget to submit your application through our website! It’s the best way to ensure it gets to the right people. Plus, you’ll find all the details you need to complete your application there.
How to prepare for a job interview at Diamond Light Source
✨Know Your CryoEM Inside Out
Make sure you brush up on your cryo-electron microscopy knowledge. Be prepared to discuss specific techniques like cryoFIB/SEM and sub-tomogram averaging, as well as your past experiences with these methods. This will show that you’re not just familiar with the field but are genuinely passionate about it.
✨Showcase Your Leadership Skills
As a Principal EM Scientist, you'll be leading a team. Think of examples from your past where you've successfully managed projects or mentored others. Be ready to share how you can inspire and guide a small team towards establishing a competitive research programme at eBIC.
✨Prepare for Funding Discussions
Since securing funding is part of the role, come prepared with ideas on how you would approach grant applications. Familiarise yourself with national and international funding agencies and think about how your research aligns with their priorities. This will demonstrate your proactive approach to building your research programme.
✨Engage with the Interviewers
Remember, interviews are a two-way street! Prepare thoughtful questions about the eBIC's current projects, user programmes, and future directions. This shows your genuine interest in the role and helps you assess if the environment is the right fit for you.
