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- Tasks: Lead and support clinical studies using advanced statistical methods in Rare Disease.
- Company: Cytel Inc., a leader in biostatistics with a collaborative hybrid work culture.
- Benefits: Competitive salary, flexible working hours, and opportunities for professional growth.
- Why this job: Make a real impact in healthcare by contributing to groundbreaking clinical research.
- Qualifications: Master's degree in statistics; 8+ years in clinical trials; strong SAS programming skills.
- Other info: Join a dynamic team and enjoy excellent career advancement opportunities.
The predicted salary is between 43200 - 72000 £ per year.
As Principal Biostatistician, adept at utilizing advanced statistical methods, you will support or lead one or more Phase I-III clinical studies, with a focus on multiple therapeutic areas, particularly Rare Disease.
Responsibilities
- Providing statistical support to clinical studies, with a focus on Rare Disease;
- Participating in the development of study protocols, including participation in study design discussions and sample size calculations;
- Reviewing CRFs and data review guidelines; developing statistical analysis plans (SAPs), including analysis dataset and TLG specifications;
- Performing statistical analyses;
- Interpreting statistical results;
- Preparing clinical study reports, including integrated summaries for submissions;
- Leading study activities when called upon;
- Utilizing your strong communication skills to present and explain methodology and consequences of decisions in lay terms;
- Serving as a team player, with a willingness to go the extra distance to get results, meet deadlines, etc.
Qualifications
- Master's degree in statistics or a related discipline. PhD strongly desired.
- 8+ years supporting clinical trials in the Pharmaceutical or Biotechnology industry. Experience working for a CRO strongly desired.
- Experience in sample size calculation, protocol concept development, protocol development, SAP and preparing clinical study reports including integrated summaries for submissions.
- Knowledge and implementation of advanced statistical methods, like longitudinal data analyses, missing data imputations, Survival analyses, etc.
- Good SAS programming skills for QCing critical outputs, Efficacy/Safety tables and working closely with Programmers. Knowledge of R programming a plus.
- Strong knowledge of ICH guidelines.
- Solid understanding & implementation of CDISC requirements for regulatory submissions.
- Adept in ADaM specifications generation and QC of datasets.
- Submissions experience is preferred.
- Experience working with cross-functional teams and representing the statistics group.
- Effective communicator: able to explain methodology and consequences of decisions in lay terms.
- Team player; willingness to go the extra distance to get results, meet deadlines, etc.
- Ability to be flexible when priorities change and deal with ambiguity.
Principal Biostatistician FSP - Hybrid Model United Kingdom (Hybrid) Posted on 12/05/2025 Be th[...] in London employer: Cytel Inc
Contact Detail:
Cytel Inc Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Principal Biostatistician FSP - Hybrid Model United Kingdom (Hybrid) Posted on 12/05/2025 Be th[...] in London
✨Tip Number 1
Network like a pro! Reach out to your connections in the industry, attend relevant events, and engage with professionals on platforms like LinkedIn. We all know that sometimes it’s not just what you know, but who you know that can help you land that Principal Biostatistician role.
✨Tip Number 2
Prepare for interviews by brushing up on your statistical methods and clinical trial knowledge. We recommend practising common interview questions and even doing mock interviews with friends or mentors. This way, you’ll be ready to showcase your expertise and communication skills when it counts!
✨Tip Number 3
Don’t underestimate the power of follow-ups! After an interview, send a thank-you email to express your appreciation and reiterate your interest in the position. It shows you’re proactive and genuinely excited about the opportunity, which can set you apart from other candidates.
✨Tip Number 4
Apply through our website! We make it easy for you to find and apply for roles like the Principal Biostatistician. Plus, it ensures your application gets the attention it deserves. So, don’t hesitate – get your application in and let’s get you that dream job!
We think you need these skills to ace Principal Biostatistician FSP - Hybrid Model United Kingdom (Hybrid) Posted on 12/05/2025 Be th[...] in London
Some tips for your application 🫡
Tailor Your CV: Make sure your CV is tailored to the Principal Biostatistician role. Highlight your experience in clinical trials, especially in Rare Disease, and showcase your advanced statistical skills. We want to see how your background aligns with what we're looking for!
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you're passionate about biostatistics and how your expertise can contribute to our team. Keep it engaging and relevant to the job description – we love a good story!
Showcase Your Communication Skills: Since effective communication is key in this role, make sure to demonstrate your ability to explain complex statistical concepts in simple terms. Whether it's in your CV or cover letter, let us know how you’ve successfully communicated with cross-functional teams in the past.
Apply Through Our Website: We encourage you to apply directly through our website. It’s the best way to ensure your application gets into the right hands. Plus, it shows us that you’re genuinely interested in joining our team at StudySmarter!
How to prepare for a job interview at Cytel Inc
✨Know Your Stats
Brush up on your advanced statistical methods, especially those relevant to clinical trials and rare diseases. Be ready to discuss how you've applied these methods in past projects, as this will show your expertise and confidence.
✨Protocol Proficiency
Familiarise yourself with the development of study protocols and statistical analysis plans (SAPs). Prepare to explain your experience with sample size calculations and how you’ve contributed to protocol discussions in previous roles.
✨Communication is Key
Practice explaining complex statistical concepts in simple terms. This is crucial for conveying your methodology and results to non-statistical team members. We recommend using examples from your past work to illustrate your points.
✨Team Player Attitude
Demonstrate your willingness to collaborate and go the extra mile. Share examples of how you've worked effectively within cross-functional teams and adapted to changing priorities, as this aligns with what they’re looking for in a candidate.
