At a Glance
- Tasks: Lead innovative animal model studies and design impactful preclinical research in oncology.
- Company: Exciting early-stage biotech with a focus on programmable therapeutics for cancer.
- Benefits: Join a pivotal growth phase with opportunities to shape future clinical strategies.
- Other info: Collaborate with a dynamic team and contribute to groundbreaking therapeutic developments.
- Why this job: Make a real difference in cancer treatment by working at the forefront of biotechnology.
- Qualifications: PhD in relevant field and 5+ years of hands-on experience in cell biology.
The predicted salary is between 80000 - 100000 £ per year.
An exciting opportunity has arisen to join a newly funded, early-stage biotechnology company developing a highly ambitious programmable therapeutics platform for oncology. Having recently secured significant seed funding, the company is now expanding its scientific team as it moves from platform validation towards deeper preclinical development across multiple cancer indications. Their technology is focused on using programmable biology to recognise disease-defining genetic features and selectively eliminate target cells, opening the potential to address areas of oncology that remain difficult to drug through conventional therapeutic approaches.
This is a high-impact opportunity for a scientist who can bridge in vitro cell biology with in vivo pharmacology, generating the preclinical efficacy, biodistribution, safety and translational data that will shape the company’s path toward the clinic.
Why Join?
- Join a recently seed-funded biotech at a pivotal stage of growth
- Help build a novel oncology platform targeting disease biology at the genetic level
- Play a central role in shaping preclinical strategy across multiple indications
- Work at the intersection of in vivo pharmacology, translational biology, gene editing and oncology
- Take ownership of studies that will directly influence future clinical development
About the Role
You will lead animal model and translational biology programmes across multiple oncology indications. The role will involve designing and overseeing studies in disease-relevant animal models, coordinating with CRO partners, and generating the preclinical datasets needed to support therapeutic development. This position will suit a scientist who is equally comfortable designing mouse studies, interpreting biodistribution data, working hands-on with cell-based models and translating complex biological findings into actionable development decisions.
Key responsibilities:
- Designing and monitoring in vivo efficacy and biodistribution studies across multiple oncology indications
- Leading animal model studies and coordinating outsourced work with CRO partners
- Designing and executing immunogenicity assessments, including anti-Cas human PBMC ELISpot screens for pre-existing immunity and redosing scenarios
- Establishing and running patient-derived organoid assay panels to evaluate therapeutic selectivity
- Defining pharmacodynamic readout strategies, including tumour molecular analysis and biomarker monitoring
- Performing hands-on cell line experiments to support translational studies
- Interpreting preclinical efficacy, safety, biodistribution and pharmacodynamic data to inform programme direction
- Working closely with internal scientific leadership and external partners to progress programmes toward the clinic
About the Candidate
Essential
- PhD in Cancer Biology, Pharmacology, Immunology or a related discipline
- 5+ years of hands-on in vivo and in vitro cell line experience
- Experience working with bladder cancer, liver cancer and/or lung cancer models
- Experience with local or intravesical delivery in rodent models
- Strong understanding of biodistribution study design and tissue analysis techniques, including qPCR and IHC
- Hands-on patient-derived organoid culture and functional assay experience
- Familiarity with immunology assays, including ELISpot
- Experience designing, managing and interpreting outsourced studies with CRO partners
Desirable
- Experience with GLP-adjacent or GLP-compliant preclinical studies
- Familiarity with Australian and/or US regulatory frameworks for animal studies
- Prior experience working on in vivo gene therapy or gene editing programmes
- Experience contributing to preclinical packages supporting IND-enabling development
This is an excellent opportunity to join a recently funded oncology biotech at an early and highly influential stage, working on a novel therapeutic platform with the potential to reshape how genetically defined cancers are targeted.
Senior Cell Biologist in London employer: CT19
Join a pioneering biotechnology company at the forefront of oncology innovation, where your contributions will directly impact the development of groundbreaking programmable therapeutics. With a strong focus on employee growth and collaboration, we foster a dynamic work culture that encourages scientific exploration and creativity. Located in a vibrant area, our team enjoys access to cutting-edge resources and a supportive environment that values each member's expertise and insights.
StudySmarter Expert Advice🤫
We think this is how you could land Senior Cell Biologist in London
✨Get Involved in Local Research Communities
Tap into local biotechnology meetups and research forums. These are great places to mingle with industry professionals, share your passion, and even discover unadvertised job openings. It's all about getting your face known in the field!
✨Leverage University Alumni Networks
If you're a recent grad, don’t underestimate the power of your university’s alumni network! Reach out to alumni working in biotechnology to gather tips about job openings at companies like CT19. You'd be surprised how willing people are to help out a fellow grad!
✨Show Off Your Projects
Curate a portfolio showcasing any research projects or internships you've completed in biotechnology. This tangible evidence of your skills can really impress employers when you chat with them at networking events or interviews. It's about making that killer first impression!
✨Stay Up-to-Date with Industry Trends
Biotech is a fast-paced field, so keeping yourself updated with the latest advancements is crucial. Attend industry conferences, webinars, or workshops to broaden your knowledge and meet potential employers. Plus, it’ll give you fantastic talking points for your interviews at places like CT19!
We think you need these skills to ace Senior Cell Biologist in London
Some tips for your application 🫡
Show Off Your Lab Skills:In the biotechnology field, it's super important to highlight your lab experience in your CV. Be sure to mention specific techniques or instruments you've mastered (think PCR, gel electrophoresis, etc.) and any relevant projects you've worked on. This will show CT19 that you have the hands-on skills they need.
Tailor Your Technical Skills:Make sure to emphasise your technical skills, especially those relevant to the biotechnology sector. Include any software tools or programming languages you've used, like R or Python for data analysis, which could be key for this role at CT19.
Craft a Compelling Cover Letter:Since this is a full-time role, your cover letter should reflect not only your passion for biotechnology but also your long-term career ambitions. Share why you're excited about the work that CT19 does and how you envision contributing to their goals. This shows that you’re not just looking for any job, but you're genuinely invested in this opportunity.
Include Your Papers and Projects:If you've published any papers or contributed to significant projects, mention them! These documents can boost your application and provide tangible evidence of your expertise in the biotechnology field. Don’t forget to link to any relevant publications or project summaries—this can set you apart from other candidates.
How to prepare for a job interview at CT19
✨Brush Up on Lab Techniques
Since you're eyeing a full-time gig in biotechnology, make sure you're well-versed in the lab techniques relevant to the role. Be ready to talk about PCR, CRISPR, or any specific methods mentioned in the job description at CT19. You might even be asked to demonstrate your understanding of these processes.
✨Know Your Bioinformatics Tools
Get comfortable with bioinformatics tools that are commonly used in the industry, like BLAST or Bioconductor. These are key in biotechnology, and having hands-on experience or at least familiarity can set you apart. Prepare to discuss any relevant projects you've worked on, especially if they involved data analysis or genomic research.
✨Show Your Teamwork Skills
Biotech often involves collaboration across multiple disciplines. Be ready to share stories that highlight your teamwork and communication skills, especially in research projects. Think about working with different teams at university or any internships – this is where you can show how well you fit into CT19's culture.
✨Research Recent Biotech Innovations
Stay updated on the latest trends and breakthroughs in biotechnology. Knowing what's happening in the field can help you engage in more meaningful discussions during your interview. Bring up recent articles or advancements that excite you, especially those related to the work being done at CT19. This shows your passion for the industry!
