At a Glance
- Tasks: Execute hands-on cell biology assays to drive cancer treatment innovations.
- Company: Exciting early-stage biotech focused on programmable therapeutics for oncology.
- Benefits: Join a dynamic team with growth potential and impactful work in cancer research.
- Other info: Opportunity to shape therapeutic candidates in a fast-paced, innovative environment.
- Why this job: Be at the forefront of developing selective therapies that could change cancer treatment.
- Qualifications: Experience in cell biology, mammalian cell culture, and flow cytometry required.
The predicted salary is between 40000 - 50000 £ per year.
An exciting opportunity has arisen to join a newly funded, early-stage biotechnology company developing a highly ambitious programmable therapeutics platform for oncology. Having recently secured significant seed funding, the company is expanding its biology team as it progresses from platform validation into preclinical development across multiple cancer indications. Their technology is focused on engineering programmable therapeutic systems that can distinguish cancer cells from normal tissue based on disease-defining biology, with the aim of creating a more selective approach to oncology treatment.
This is a hands-on cell biology role at the centre of the company’s discovery and preclinical engine. You will generate the in vitro data that determines whether therapeutic constructs selectively activate in cancer cells while sparing normal tissue, directly informing which candidates progress toward animal studies and further development.
Why Join?
- Join a recently seed-funded biotech at a pivotal stage of scientific growth
- Work on a novel oncology platform designed around programmable, target-selective therapeutic biology
- Generate the key in vitro data that drives construct selection and programme advancement
- Work across multiple oncology programmes using diverse cancer and normal cell line panels
- Play a central role in shaping which candidates move into in vivo studies and preclinical development
About the Role
As Cell Biology Scientist, you will execute the in vitro assays that determine whether therapeutic constructs selectively activate in cancer cells while sparing normal tissue. Working across multiple oncology programmes, you will maintain a diverse panel of cancer and normal cell lines, run high-throughput discrimination assays, and generate quantitative data to support construct selection and programme progression. This is a highly hands-on role suited to a scientist who is comfortable managing parallel experiments, working with mammalian cell culture systems and producing rigorous, well-documented assay data. Your work will sit at the interface of cell biology, CRISPR-based therapeutic development, oncology and preclinical translation.
Key responsibilities
- Executing target-selective kill-discrimination assays across multiple oncology programmes using panels of cancer and normal cell lines
- Generating dose-response, multiplexing and specificity data in support of preclinical data packages
- Maintaining mammalian cell cultures across a diverse panel of cancer and normal cell lines
- Performing flow cytometry, including multi-colour analysis and sorting
- Running viability, cytotoxicity and apoptosis assays, including CellTiter-Glo, Annexin V and PI-based assays
- Performing reporter assays, including luminescent and fluorescent readouts
- Carrying out transfection and/or electroporation of CRISPR components
- Running parallel experiments across multiple programmes with strong organisation, documentation and data integrity
- Working closely with molecular biology and translational teams to connect construct design with functional cell-based performance
About the Candidate
Essential
- BS, MS or PhD in Cell Biology, Molecular Biology, Biochemistry or a related discipline
- 3–5 years of mammalian cell culture experience, including work with cancer cell lines
- Experience working with diverse cell line panels across cancer and normal tissue models
- Proficiency in flow cytometry, including multi-colour analysis and cell sorting
- Experience with cell viability and cytotoxicity assays, such as CellTiter-Glo, Annexin V and PI
- Experience with transfection and/or electroporation of CRISPR components
- Strong organisational skills with the ability to manage multiple parallel experiments
- Rigorous approach to experimental documentation, assay execution and data quality
Desirable
- Experience with CRISPR editing readout methods, including T7E1, ICE and/or amplicon NGS
- Hands-on experience with luminescence or fluorescence reporter assay systems
- Experience supporting construct selection or candidate progression in a discovery or preclinical setting
- Prior experience working in a fast-moving biotech or platform biology environment
This is an excellent opportunity for a hands-on cell biology scientist to join a recently funded oncology biotech at an early and highly influential stage, generating the data that will directly shape which therapeutic candidates advance toward preclinical development.
Cell Biologist in London employer: CT19
Join a pioneering biotechnology company at the forefront of oncology innovation, where your contributions will directly influence the development of groundbreaking programmable therapeutics. With a strong focus on employee growth and a collaborative work culture, this role offers you the chance to engage in meaningful research while working alongside passionate professionals in a dynamic environment. Benefit from the excitement of being part of a newly funded venture that values creativity and scientific excellence, all while making a significant impact in the fight against cancer.
StudySmarter Expert Advice🤫
We think this is how you could land Cell Biologist in London
✨Get Involved in Local Research Communities
Tap into local biotechnology meetups and research forums. These are great places to mingle with industry professionals, share your passion, and even discover unadvertised job openings. It's all about getting your face known in the field!
✨Leverage University Alumni Networks
If you're a recent grad, don’t underestimate the power of your university’s alumni network! Reach out to alumni working in biotechnology to gather tips about job openings at companies like CT19. You'd be surprised how willing people are to help out a fellow grad!
✨Show Off Your Projects
Curate a portfolio showcasing any research projects or internships you've completed in biotechnology. This tangible evidence of your skills can really impress employers when you chat with them at networking events or interviews. It's about making that killer first impression!
✨Stay Up-to-Date with Industry Trends
Biotech is a fast-paced field, so keeping yourself updated with the latest advancements is crucial. Attend industry conferences, webinars, or workshops to broaden your knowledge and meet potential employers. Plus, it’ll give you fantastic talking points for your interviews at places like CT19!
We think you need these skills to ace Cell Biologist in London
Some tips for your application 🫡
Show Off Your Lab Skills:In the biotechnology field, it's super important to highlight your lab experience in your CV. Be sure to mention specific techniques or instruments you've mastered (think PCR, gel electrophoresis, etc.) and any relevant projects you've worked on. This will show CT19 that you have the hands-on skills they need.
Tailor Your Technical Skills:Make sure to emphasise your technical skills, especially those relevant to the biotechnology sector. Include any software tools or programming languages you've used, like R or Python for data analysis, which could be key for this role at CT19.
Craft a Compelling Cover Letter:Since this is a full-time role, your cover letter should reflect not only your passion for biotechnology but also your long-term career ambitions. Share why you're excited about the work that CT19 does and how you envision contributing to their goals. This shows that you’re not just looking for any job, but you're genuinely invested in this opportunity.
Include Your Papers and Projects:If you've published any papers or contributed to significant projects, mention them! These documents can boost your application and provide tangible evidence of your expertise in the biotechnology field. Don’t forget to link to any relevant publications or project summaries—this can set you apart from other candidates.
How to prepare for a job interview at CT19
✨Brush Up on Lab Techniques
Since you're eyeing a full-time gig in biotechnology, make sure you're well-versed in the lab techniques relevant to the role. Be ready to talk about PCR, CRISPR, or any specific methods mentioned in the job description at CT19. You might even be asked to demonstrate your understanding of these processes.
✨Know Your Bioinformatics Tools
Get comfortable with bioinformatics tools that are commonly used in the industry, like BLAST or Bioconductor. These are key in biotechnology, and having hands-on experience or at least familiarity can set you apart. Prepare to discuss any relevant projects you've worked on, especially if they involved data analysis or genomic research.
✨Show Your Teamwork Skills
Biotech often involves collaboration across multiple disciplines. Be ready to share stories that highlight your teamwork and communication skills, especially in research projects. Think about working with different teams at university or any internships – this is where you can show how well you fit into CT19's culture.
✨Research Recent Biotech Innovations
Stay updated on the latest trends and breakthroughs in biotechnology. Knowing what's happening in the field can help you engage in more meaningful discussions during your interview. Bring up recent articles or advancements that excite you, especially those related to the work being done at CT19. This shows your passion for the industry!
