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- Tasks: Lead innovative cancer research and develop preclinical models to enhance treatment efficacy.
- Company: Join the CRUK National Biomarker Centre, a leader in cancer research.
- Benefits: Enjoy a competitive pension scheme, health services, and generous leave entitlements.
- Why this job: Make a real impact in cancer therapeutics and collaborate with top researchers.
- Qualifications: PhD in Biological Sciences with expertise in cancer pharmacology and project management.
- Other info: Be part of a vibrant, multidisciplinary ecosystem at the Manchester Cancer Research Centre.
The predicted salary is between 55000 - 65000 £ per year.
About the role: The mission of the CRUK National Biomarker Centre (NBC) is to discover, develop, validate and qualify biomarkers that support optimised treatment of patients with cancer. An exciting opportunity exists to become the Deputy Team Lead of the NBC Preclinical Pharmacology (PP) Team. We seek an innovative and accomplished translational scientist with significant post-doctoral experience in cancer therapeutics and biomarker development to strategically develop our portfolio of preclinical cancer models and ex vivo approaches. Your goal is to enhance our mission to validate and credential new drug targets, to determine therapeutic efficacy, toxicity and resistance mechanisms and to discover and develop predictive, pharmacodynamic and response-monitoring biomarkers.
You will have expertise in preclinical models of cancer (patient-derived and immune-competent models) and be well-versed in drug efficacy and resistance studies. You will bring innovative ideas and have expertise in a range of ex vivo protocols to interrogate drug mechanisms and cellular impacts of drug/target interactions. You will work closely with the PP Team Lead, influencing the strategic direction and oversee day-to-day operational aspects of the PP Team’s research with line management responsibilities. You will be an effective networker, engaging collaborators in the Pharmaceutical and Biotech industry and will drive and contribute to grant submissions and publication outputs. You will relish the opportunity to interact with the other biomarker teams in the NBC, to collaborate with investigators at the CRUK Manchester Institute and will maximise the location of the NBC within the Manchester Cancer Research Centre.
About You: You should have a PhD in Biological Sciences, ideally in cancer pharmacology or cancer biology and/or a related discipline. You will possess comprehensive knowledge of personalised cancer medicines and will have experience in designing and running both in vitro and in vivo preclinical cancer therapeutics studies. You will have experience in management of integrated multidisciplinary project teams and an ability to effectively communicate between different specialists. This role is the perfect opportunity for an ambitious, collaborative and self-motivated individual looking to accelerate the success of the PP team with independent ideas and contribute to its strategic direction within the NBC mission.
What you will get in return: Fantastic market leading Pension scheme, Excellent employee health and wellbeing services including an Employee Assistance Programme, Exceptional starting annual leave entitlement, plus bank holidays, Local and national discounts at a range of major retailers.
Why choose the CRUK National Biomarker Centre? Within the University of Manchester, we are an internationally recognised cancer biomarker centre closely aligned to the world leading Cancer Research UK Manchester Institute. Both The CRUK National Biomarker Centre and CRUK Manchester Institute are core funded by Cancer Research UK, the largest independent cancer research organiser in the world. We are partnered with The Christie NHS Foundation Trust, one of the largest cancer treatment centres in Europe. CRUK, The University of Manchester and The Christie are strategically aligned under the umbrella of the Manchester Cancer Research Centre (MCRC) forming a vibrant, patient facing, multi-disciplinary ecosystem for Cancer Research. The CRUK National Biomarker Centre is located within the New Paterson Building, a £150 million flagship purpose-built biomedical research facility directly attached to The Christie hospital in South Manchester. Situated across the third floor, the NBC offers world-class research facilities with a bespoke suite of laboratories adjacent to exceptional discovery, translational and clinical research collaborators including the Christie’s clinical trialists, offering unrivalled opportunity for biomarker research.
How to apply? To apply for this position please visit our website. Please ensure you detail the names of three referees and ensure you submit your application before 10 May 2026 Sunday. Please note this vacancy will close for applications at 18:00 hours on the closing date specified. Informal enquiries to the NBC Director Prof Caroline Dive and PP Team Lead Dr Kathryn Simpson.
Deputy Preclinical Pharmacology Team Lead in Manchester employer: CRUK National Biomarker Centre
Contact Detail:
CRUK National Biomarker Centre Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Deputy Preclinical Pharmacology Team Lead in Manchester
✨Tip Number 1
Network like a pro! Reach out to professionals in the cancer research field, especially those connected to the CRUK National Biomarker Centre. Attend relevant conferences or webinars to make connections and show your enthusiasm for the role.
✨Tip Number 2
Prepare for the interview by brushing up on your knowledge of preclinical models and biomarker development. Be ready to discuss your past experiences and how they align with the mission of the NBC. We want to see your passion for cancer therapeutics!
✨Tip Number 3
Showcase your collaborative spirit! Highlight any previous teamwork experiences, especially in multidisciplinary settings. The more we see your ability to work with others, the better your chances of landing that Deputy Team Lead position.
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets noticed. Make sure to include those three referees and submit before the deadline – we’re excited to see what you bring to the table!
We think you need these skills to ace Deputy Preclinical Pharmacology Team Lead in Manchester
Some tips for your application 🫡
Tailor Your CV: Make sure your CV is tailored to the role of Deputy Preclinical Pharmacology Team Lead. Highlight your post-doctoral experience in cancer therapeutics and any relevant projects that showcase your expertise in preclinical models and biomarker development.
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you're passionate about cancer research and how your innovative ideas can contribute to our mission at the CRUK National Biomarker Centre. Be sure to mention specific experiences that align with the job description.
Showcase Your Collaboration Skills: Since this role involves engaging with collaborators in the Pharmaceutical and Biotech industry, make sure to highlight any past experiences where you've successfully worked in multidisciplinary teams. We love seeing how you can communicate effectively across different specialisms!
Apply Through Our Website: Don't forget to apply through our website! It's the best way to ensure your application gets to us directly. Remember to include the names of three referees and submit everything before the deadline on 10 May 2026 at 18:00 hours.
How to prepare for a job interview at CRUK National Biomarker Centre
✨Know Your Science
Make sure you brush up on the latest advancements in cancer pharmacology and biomarker development. Be ready to discuss your post-doctoral research and how it aligns with the mission of the CRUK National Biomarker Centre.
✨Showcase Your Leadership Skills
As a Deputy Team Lead, you'll need to demonstrate your ability to manage multidisciplinary teams. Prepare examples of past experiences where you've successfully led projects or collaborated with various specialists.
✨Engage with Their Mission
Familiarise yourself with the NBC's goals and recent publications. During the interview, express your enthusiasm for their work and how your innovative ideas can contribute to their strategic direction.
✨Network Like a Pro
Highlight your networking skills and any collaborations you've had with the Pharmaceutical and Biotech industry. Be prepared to discuss how you can leverage these connections to drive grant submissions and publication outputs.