Principal Software Engineer (AI / Healthcare) — Europe / Remote in London
Principal Software Engineer (AI / Healthcare) — Europe / Remote

Principal Software Engineer (AI / Healthcare) — Europe / Remote in London

London Full-Time 60000 - 84000 £ / year (est.) No home office possible
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At a Glance

  • Tasks: Develop AI systems that transform healthcare delivery and improve patient outcomes.
  • Company: Stealth healthcare AI startup backed by top-tier venture capital.
  • Benefits: Competitive salary, equity options, and remote work flexibility.
  • Why this job: Make a real impact in healthcare with cutting-edge AI technology.
  • Qualifications: Senior-level experience in software engineering, especially with Python.
  • Other info: High ownership role with excellent growth opportunities in a dynamic environment.

The predicted salary is between 60000 - 84000 £ per year.

Our client is a stealth healthcare AI startup backed by a top-tier global venture capital firm, founded by experienced entrepreneurs with a strong track record in healthtech and large-scale consumer platforms. Their mission is ambitious: to automate GP-level diagnosis using AI agents, transforming how healthcare is accessed and delivered globally.

This is a hands-on Principal Software Engineer role for someone who wants to operate at the intersection of AI, healthcare, and distributed systems, working directly with real hospitals and clinics to deploy production-grade solutions.

What You'll Work On

  • Deploy and refine enterprise-grade AI systems used in real healthcare environments
  • Build AI-driven patient communication and triage systems
  • Design and operate agent orchestration frameworks with strong guardrails
  • Develop secure healthcare data layers with strict privacy and compliance requirements
  • Implement low-latency voice and video systems for clinical use cases
  • Solve complex problems in distributed systems, scalability, and enterprise integration
  • Work closely with hospitals, clinics, and internal stakeholders to ship real-world solutions

Tech Stack & Focus

  • Primary language: Python (core requirement)
  • AI systems for patient communication and decision support
  • Distributed systems at scale
  • Secure data architectures for healthcare
  • Enterprise integrations and production deployments
  • Flexibility to use other languages where appropriate for senior engineers

What We're Looking For

  • Senior / Principal-level software engineering experience
  • Strong expertise in Python and production systems
  • Experience working with hospitals, clinics, or regulated healthcare environments
  • Proven ability to deploy and maintain enterprise-grade systems
  • Comfort operating in ambiguous, high-impact problem spaces
  • Strong ownership mindset and ability to work autonomously

Why This Role?

  • Direct impact on real healthcare outcomes, not experiments
  • Work on doctor-level AI agents, not superficial automation
  • Backed by top-tier investors with long-term vision
  • High ownership, high trust, and minimal bureaucracy
  • Competitive compensation with meaningful equity upside

Who This Role Is Not For

  • Engineers looking for purely academic or research-only roles
  • Candidates uncomfortable with production responsibility
  • Those preferring narrow scope or rigid processes

Apply now if you want to build AI systems that operate at the heart of healthcare — at scale, in production, and with real-world impact.

Principal Software Engineer (AI / Healthcare) — Europe / Remote in London employer: Cross Border Talents

Join a pioneering stealth healthcare AI startup that is redefining the future of medical diagnosis through innovative technology. With a strong focus on employee growth and a collaborative work culture, you will have the opportunity to make a tangible impact on healthcare outcomes while enjoying competitive compensation and equity options. Our remote-friendly environment fosters autonomy and creativity, allowing you to thrive in a dynamic setting alongside experienced professionals dedicated to transforming healthcare delivery.
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Contact Detail:

Cross Border Talents Recruiting Team

StudySmarter Expert Advice 🤫

We think this is how you could land Principal Software Engineer (AI / Healthcare) — Europe / Remote in London

Tip Number 1

Network like a pro! Reach out to folks in the healthcare AI space on LinkedIn or at industry events. A personal connection can often get your foot in the door faster than any application.

Tip Number 2

Show off your skills! Create a portfolio showcasing your projects, especially those related to AI and healthcare. This gives potential employers a taste of what you can do and sets you apart from the crowd.

Tip Number 3

Prepare for interviews by brushing up on your problem-solving skills. Expect to tackle real-world scenarios that reflect the challenges faced in healthcare AI. Practice makes perfect!

Tip Number 4

Don’t forget to apply through our website! It’s the best way to ensure your application gets seen by the right people. Plus, we love seeing candidates who are proactive about their job search.

We think you need these skills to ace Principal Software Engineer (AI / Healthcare) — Europe / Remote in London

Python
AI Systems Development
Distributed Systems
Enterprise Integration
Secure Data Architectures
Healthcare Compliance
Low-Latency Systems
Problem-Solving in Complex Environments
Autonomous Work Ethic
Stakeholder Collaboration
Production System Deployment
Patient Communication Systems
Agent Orchestration Frameworks
Scalability Solutions

Some tips for your application 🫡

Tailor Your CV: Make sure your CV reflects the skills and experiences that align with the role. Highlight your expertise in Python and any experience you have in healthcare environments. We want to see how you can bring value to our mission!

Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Share your passion for AI and healthcare, and explain why you're excited about this role. We love seeing genuine enthusiasm, so let your personality come through!

Showcase Relevant Projects: If you've worked on projects related to AI systems or healthcare, make sure to mention them. We’re interested in real-world applications, so share any examples of how you've tackled complex problems in distributed systems.

Apply Through Our Website: We encourage you to apply directly through our website. It’s the best way for us to receive your application and ensures you don’t miss out on any important updates. Plus, we love seeing candidates who take that extra step!

How to prepare for a job interview at Cross Border Talents

Know Your Tech Stack Inside Out

Make sure you’re well-versed in Python and the specific technologies mentioned in the job description. Brush up on your experience with AI systems, distributed systems, and secure data architectures. Being able to discuss your past projects in detail will show that you’re not just familiar with the tech but can also apply it effectively.

Understand the Healthcare Landscape

Since this role is focused on healthcare, take some time to research current trends and challenges in the industry. Familiarise yourself with how AI is being used in healthcare settings, especially in patient communication and triage systems. This knowledge will help you demonstrate your genuine interest and understanding of the field during the interview.

Prepare for Problem-Solving Questions

Expect to face complex problem-solving scenarios related to distributed systems and scalability. Practice articulating your thought process clearly and logically. Use examples from your previous work where you successfully tackled similar challenges, as this will showcase your hands-on experience and ownership mindset.

Showcase Your Collaboration Skills

This role involves working closely with hospitals and clinics, so be ready to discuss your experience collaborating with various stakeholders. Highlight instances where you’ve worked autonomously but also engaged with teams to deliver impactful solutions. This balance will illustrate your ability to thrive in a high-trust environment.

Principal Software Engineer (AI / Healthcare) — Europe / Remote in London
Cross Border Talents
Location: London

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