At a Glance
- Tasks: Conduct groundbreaking research on autoimmune diseases and TLR7 signalling.
- Company: Join the Francis Crick Institute, Europe's largest biomedical research hub.
- Benefits: Enjoy a competitive salary, generous leave, and health support.
- Other info: Collaborative environment with excellent career growth opportunities.
- Why this job: Make a real impact in immunology and improve patient outcomes.
- Qualifications: PhD in Immunology and experience with mouse models required.
The predicted salary is between 47500 - 47500 € per year.
Salary for this Role: From £47,500 with benefits subject to skills and experience.
Reports to: Carola Vinuesa
Closing Date: 01/Jun/2026 23.59 GMT
Details of the role:
This is a full-time, 4 year fixed term position on Crick terms and conditions of employment.
About us
The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.
The Research Group
Dr Vinuesa’s laboratory focuses on understanding the regulation of protective antibody responses and the mechanisms underpinning antibody-mediated diseases. The research aims to unravel the pathogenesis of autoimmune and allergic diseases, and the processes that control the quality of antibody responses.
The Project
The purpose of this role is to study the role of different triggers of TLR7 signalling including bacterial and viral infections to the onset of autoimmunity.
What you will be doing
- Undertaking own research project and independently designing and performing experiments to study different triggers of TLR7 signalling including bacterial and viral infections to the onset of autoimmunity
- Mouse colony management and independently conducting in-vivo experiments
- Conducting single cell BCRseq and clonal analysis using bioinformatic pipelines
- Scientific and technical support for group members
- Data management and analysis, writing up of manuscripts
- Presenting at scientific meetings
- Guiding PhDs in their research
About you
- PhD in Immunology or in the final stages of PhD submission
- Experience in mouse models of immunology, including mouse models of vaccination, allergy, and autoimmunity
- Experience with mouse husbandry, sample harvesting and processing
- Expertise in multiple aspects of B cell biology, including germinal center and extrafollicular responses, plasma cell biology, class switch recombination and somatic hypermutation
- Experience in BCR sequencing and clonal analysis
- Experience in mucosal immunology and mucosal B cell responses
- Excellent track record of high-quality research as evidenced by first author publications in referred journals
About Working at the Crick
Our values: Everyone who works at the Crick has a valuable role to play in advancing the Crick’s mission and shaping our culture. We are bold. We make space for creative, dynamic and imaginative ideas and approaches. We’re not afraid to do things differently. We are open. We’re highly collaborative and interactive, and make sure our activities are visible to the outside world. We are collegial. We show respect for one another, work cooperatively and support the wider community.
At the Francis Crick Institute, we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued, respected, and empowered to succeed, regardless of their background, identity, or personal circumstances.
What will you receive?
- Visas: Applicants for this role will be eligible for sponsorship to work in the UK
- Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays
- Pension Scheme: Defined contribution pension with employer contributions of up to 16%
- Health & Well-being: 24/7 GP consultation services, occupational health services and mental health support programs, eye care vouchers and discounted healthcare plans
- Work-Life Balance: Back-up care for dependents, childcare support allowance, annual leave purchase options
- Perks: Discounted gym memberships, bike-to-work scheme, and shopping discounts, subsidised on-site restaurant and social spaces for team interaction
Please note you must meet the essential criteria listed within the Role Profile, to have your application reviewed.
Postdoctoral Fellow – Vinuesa Lab employer: Crick Group
The Francis Crick Institute is an exceptional employer, offering a dynamic and collaborative work environment that fosters innovation and scientific exploration. With generous benefits including 28 days of annual leave, a robust pension scheme, and extensive health and well-being support, employees are empowered to thrive both personally and professionally. Located in London, the institute provides unique opportunities for growth and development in cutting-edge biomedical research, making it an ideal place for those passionate about advancing human health.
StudySmarter Expert Advice🤫
We think this is how you could land Postdoctoral Fellow – Vinuesa Lab
✨Tip Number 1
Network like a pro! Reach out to current or former members of the Vinuesa Lab or the Crick Institute. A friendly chat can give you insider info and maybe even a referral, which can really boost your chances.
✨Tip Number 2
Prepare for the interview by diving deep into the lab's research. Familiarise yourself with their recent publications and projects. This shows you're genuinely interested and ready to contribute to their mission.
✨Tip Number 3
Practice your pitch! Be ready to explain how your skills and experiences align with the lab's focus on autoimmune diseases. Highlight your unique contributions and how they can help advance their research.
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets seen. Plus, it shows you’re serious about joining the team at the Crick Institute.
We think you need these skills to ace Postdoctoral Fellow – Vinuesa Lab
Some tips for your application 🫡
Tailor Your Application:Make sure to customise your CV and cover letter for the Postdoctoral Fellow role. Highlight your relevant experience in immunology and mouse models, as well as any publications you've authored. We want to see how your background aligns with our research goals!
Showcase Your Research Skills:In your application, emphasise your hands-on experience with B cell biology and TLR7 signalling. Mention specific techniques you’ve mastered, like BCR sequencing or in-vivo experiments. This will help us understand your technical expertise and how you can contribute to our lab.
Be Clear and Concise:When writing your application, keep it straightforward and to the point. Use clear language and avoid jargon where possible. We appreciate a well-structured application that makes it easy for us to see your qualifications and enthusiasm for the role.
Apply Through Our Website:Don’t forget to submit your application through our official website! It’s the best way to ensure we receive all your materials correctly. Plus, it shows you’re serious about joining our team at the Crick!
How to prepare for a job interview at Crick Group
✨Know Your Research
Make sure you’re well-versed in the latest findings related to TLR7 signalling and autoimmune diseases. Familiarise yourself with Dr Vinuesa's work and be ready to discuss how your research aligns with the lab's goals.
✨Showcase Your Skills
Prepare to talk about your experience with mouse models, B cell biology, and any relevant techniques like BCR sequencing. Bring examples of your past research and publications to demonstrate your expertise.
✨Ask Insightful Questions
Think of thoughtful questions that show your interest in the lab’s projects and the broader implications of their research. This not only shows your enthusiasm but also helps you gauge if the lab is the right fit for you.
✨Emphasise Collaboration
The Crick values collaboration, so highlight your teamwork experiences. Share examples of how you've supported colleagues or guided PhD students in their research, showcasing your collegial approach.
