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- Tasks: Lead analytical workflows for nucleic acids and peptides using advanced techniques like HPLC.
- Company: Innovative biotech organisation focused on large molecule therapeutics.
- Benefits: Up to £50,000 salary, flexible hours, and generous leave.
- Why this job: Make a real impact in bioprocessing while mentoring the next generation of scientists.
- Qualifications: PhD in Analytical Chemistry or related field with hands-on HPLC experience.
- Other info: Collaborative environment with excellent career growth and social events.
The predicted salary is between 36000 - 60000 £ per year.
We’re partnering with an innovative scientific organisation to recruit a Senior Scientist with strong experience in downstream analytical processes, including HPLC and bioprocessing techniques, to join a high-performing team based in Southampton. This hands-on role offers the chance to support the development of modified nucleic acids and peptides, drive analytical method development, and contribute to the advancement of large molecule therapeutics in a collaborative, fast-paced environment.
About the Role
You’ll take the lead on analytical workflows for nucleic acids, peptides, and antibodies, ensuring high standards of quality, compliance, and scientific rigour. The role will include method development, instrument maintenance, and cross-functional collaboration across R&D and production teams. This position is ideal for a scientist who enjoys working across disciplines, mentoring junior colleagues, and staying at the forefront of analytical innovation.
Key Responsibilities
- Lead downstream analytical workflows using HPLC, UPLC, PAGE, flash chromatography, and related techniques
- Contribute to the purification and characterisation of large molecules, such as peptides and antibodies
- Support method development and continuous improvement in analytical approaches
- Collaborate with chemistry and production teams to support small molecule and oligonucleotide preparation
- Maintain, calibrate, and optimise analytical instrumentation in line with ISO and internal quality systems
- Mentor and support Associate Scientists and Lab Technicians
- Ensure accurate documentation and maintain data integrity across workflows
- Promote and uphold Health, Safety, and Environmental (HSE) standards
- Manage stock levels of analytical reagents and consumables
- Stay up to date on emerging trends in bioprocessing and analytical technologies
About You
We’re looking for a motivated and collaborative scientist with a solid grounding in downstream analytical techniques and a passion for quality science.
You’ll ideally have:
- A PhD (or equivalent experience) in Analytical Chemistry, Biochemistry, or a related field
- Strong hands-on experience in HPLC and bioprocessing within a biotechnology, pharmaceutical, or life sciences environment
- Knowledge of purification and characterisation methods for peptides, antibodies, or similar large molecules
- Experience with TFF or tangential flow filtration (advantageous)
- Familiarity with ISO or GMP-regulated environments
- Ability to lead technical projects and support team development
- Strong communication and problem-solving skills
- A flexible, proactive mindset with strong attention to detail
Salary & Benefits
Salary: Up to £50,000 depending on experience
Location: On-site in Southampton
Holidays: 25 days annual leave + 8 bank holidays
Pension: 6% employer contribution
Life Assurance: 4x salary
Additional Benefits Include:
- Flexible working hours
- Long service awards and recognition scheme
- Employee Assistance Programme with 24/7 remote GP access
- Annual flu vaccinations
- Cycle to work scheme and gym discounts
- Discounts and savings platform
- Professional membership reimbursement
- Referral incentives
- Social events and volunteering days
Senior Scientist in Southampton employer: Cranleigh STEM, Sustainability & SHEQ Recruitment
Contact Detail:
Cranleigh STEM, Sustainability & SHEQ Recruitment Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior Scientist in Southampton
✨Tip Number 1
Network like a pro! Reach out to your connections in the biotech field, especially those who work with downstream analytics. A friendly chat can lead to insider info about job openings or even a referral.
✨Tip Number 2
Prepare for interviews by brushing up on your HPLC and bioprocessing knowledge. Be ready to discuss your hands-on experience and how you've contributed to method development in past roles.
✨Tip Number 3
Show off your collaborative spirit! During interviews, highlight examples of how you've worked with cross-functional teams. This is key in a role that involves mentoring and supporting others.
✨Tip Number 4
Don’t forget to apply through our website! It’s the best way to ensure your application gets noticed. Plus, we love seeing candidates who are proactive about their job search.
We think you need these skills to ace Senior Scientist in Southampton
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights your experience with downstream analytical processes, especially HPLC and bioprocessing. We want to see how your skills align with the role, so don’t be shy about showcasing relevant projects!
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you’re passionate about large molecule therapeutics and how your background makes you a perfect fit for our team. Keep it engaging and personal.
Showcase Your Collaborative Spirit: Since this role involves cross-functional collaboration, highlight any experiences where you’ve worked with different teams. We love seeing how you can bring people together to achieve common goals!
Apply Through Our Website: We encourage you to apply directly through our website. It’s the best way for us to receive your application and ensures you’re considered for the role. Plus, it’s super easy!
How to prepare for a job interview at Cranleigh STEM, Sustainability & SHEQ Recruitment
✨Know Your Techniques
Make sure you brush up on your knowledge of HPLC, UPLC, and other downstream analytical techniques. Be ready to discuss specific projects where you've applied these methods, as well as any challenges you faced and how you overcame them.
✨Showcase Your Collaboration Skills
This role involves working closely with R&D and production teams, so be prepared to share examples of how you've successfully collaborated in the past. Highlight any mentoring experiences too, as they’ll want to see your ability to support junior colleagues.
✨Demonstrate Your Problem-Solving Abilities
Think of a few scenarios where you encountered problems in your analytical workflows and how you resolved them. This will show your potential employer that you can think critically and adapt to challenges in a fast-paced environment.
✨Stay Current with Trends
Familiarise yourself with the latest trends in bioprocessing and analytical technologies. Being able to discuss recent advancements or innovations in the field will demonstrate your passion for quality science and your commitment to staying at the forefront of the industry.
