Senior LCMS Scientist

Senior LCMS Scientist

Portsmouth +1 Full-Time 36000 - 54000 £ / year (est.) No home office possible
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At a Glance

  • Tasks: Lead analytical strategies and mentor junior scientists in a modern lab.
  • Company: Innovative scientific organisation based in Southampton.
  • Benefits: Up to £45,000 salary, flexible hours, and generous holiday allowance.
  • Why this job: Make a real impact in mass spectrometry and nucleic acid production.
  • Qualifications: PhD in Chemistry and hands-on experience with Mass Spectrometry.
  • Other info: Dynamic environment with excellent career growth and supportive culture.

The predicted salary is between 36000 - 54000 £ per year.

Senior Scientist – Subject Matter Expert (SME) in Mass Spectrometry

Up to £45,000 + Benefits

Full-time, On-site – Southampton

We’re partnering with an innovative scientific organisation to find an experienced Senior Scientist with deep expertise in Mass Spectrometry to join a high-performing team based in Southampton. This role offers the chance to lead analytical strategies, contribute to cutting-edge projects, and support the development of high-quality modified nucleic acid in a fast-paced, collaborative environment.

About the Role

As the subject matter expert in mass spectrometry, you’ll play a central role in driving analytical method development, ensuring high standards in nucleic acid production, and mentoring junior team members. This is a hands-on role in a modern laboratory, where scientific excellence and operational efficiency go hand-in-hand.

Key Responsibilities

  • Lead and manage analytical workflows using LC-MS, UPLC-MS, HPLC, PAGE, and flash chromatography
  • Act as the go-to expert for mass spectrometry, including troubleshooting and continuous improvement
  • Collaborate with cross-functional teams to support small molecule preparation and oligonucleotide synthesis
  • Maintain, calibrate, and optimise analytical instrumentation in line with internal and ISO quality standards
  • Support and mentor Associate Scientists and Lab Technicians, providing technical guidance and training
  • Ensure high levels of documentation accuracy and data integrity
  • Uphold Health, Safety and Environmental (HSE) standards and promote a safety-first culture
  • Manage the inventory of analytical reagents and consumables
  • Stay informed on emerging techniques in nucleic acid chemistry and analytical science

About You

We’re looking for a driven and detail-focused scientist who thrives in a collaborative lab environment and is passionate about pushing the boundaries of analytical science.

You’ll ideally have:

  • PhD in Chemistry, Analytical Chemistry, or a closely related field
  • Significant hands-on experience with Mass Spectrometry, ideally including Waters LC-MS systems (Waters Connect experience highly desirable)
  • Proven track record in high-throughput chemistry or oligonucleotide production environments
  • Strong grounding in nucleic acid chemistry and experience with purification techniques
  • Experience working in ISO or GMP-regulated environments
  • Ability to lead projects and mentor junior staff
  • Excellent communication, problem-solving and organisational skills
  • A proactive mindset, able to adapt and perform under pressure

Salary & Benefits

  • Salary: Up to £45,000 depending on experience
  • Location: On-site in Southampton
  • Holidays: 25 days annual leave + 8 bank holidays
  • Pension: 6% employer contribution
  • Work-Life Balance: Flexible working hours
  • Life Assurance: 4x salary
  • Other Benefits:
  • Long service awards
  • Reward and recognition scheme
  • Employee Assistance Programme with 24/7 remote GP access
  • Annual flu vaccinations
  • Cycle to work scheme
  • Gym discounts
  • Discount and savings platform
  • Professional membership reimbursement
  • Referral incentives
  • Social events and volunteering days

Want to lead innovation in mass spectrometry and oligonucleotide production?

If you\’re ready to make an impact in a dynamic and supportive environment, we’d love to hear from you. Apply today or get in touch to learn more.

Locations

Portsmouth Hampshire

Senior LCMS Scientist employer: Cranleigh STEM, Sustainability & SHEQ Recruitment

Join a pioneering scientific organisation in Southampton, where you will be part of a high-performing team dedicated to innovation in mass spectrometry and nucleic acid production. With a strong emphasis on collaboration, employee growth, and a supportive work culture, this role offers competitive benefits including flexible working hours, professional development opportunities, and a commitment to health and safety. Experience a rewarding career in a modern laboratory that values scientific excellence and operational efficiency.
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Contact Detail:

Cranleigh STEM, Sustainability & SHEQ Recruitment Recruiting Team

StudySmarter Expert Advice 🤫

We think this is how you could land Senior LCMS Scientist

✨Network Like a Pro

Get out there and connect with people in the industry! Attend conferences, workshops, or local meetups related to mass spectrometry. You never know who might have a lead on your dream job or can introduce you to someone at that innovative scientific organisation.

✨Show Off Your Skills

When you get the chance to chat with potential employers, make sure to highlight your hands-on experience with LC-MS and other analytical techniques. Share specific examples of how you've led projects or mentored junior staff to demonstrate your expertise and leadership.

✨Tailor Your Approach

Before any interview, do your homework! Research the company and its recent projects in nucleic acid chemistry. Tailor your responses to show how your background aligns with their goals and how you can contribute to their cutting-edge work.

✨Apply Through Our Website

Don’t forget to apply through our website for the best chance at landing that Senior Scientist role! We’re all about making connections and helping you find the right fit, so take advantage of our platform to showcase your skills and passion for analytical science.

We think you need these skills to ace Senior LCMS Scientist

Mass Spectrometry
LC-MS
UPLC-MS
HPLC
PAGE
Flash Chromatography
Analytical Method Development
Nucleic Acid Chemistry
Purification Techniques
ISO Quality Standards
GMP Regulations
Project Leadership
Mentoring
Communication Skills
Problem-Solving Skills

Some tips for your application 🫡

Tailor Your CV: Make sure your CV highlights your experience with mass spectrometry and analytical methods. We want to see how your skills align with the role, so don’t be shy about showcasing your relevant projects and achievements!

Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you’re passionate about this role and how your background makes you the perfect fit. We love seeing enthusiasm and a personal touch, so let your personality come through.

Showcase Your Team Spirit: Since this role involves collaboration, highlight any experiences where you’ve worked in teams or mentored others. We value a collaborative mindset, so share examples that demonstrate your ability to support and lead within a team.

Apply Through Our Website: We encourage you to apply directly through our website for a smoother application process. It’s the best way for us to receive your application and ensures you don’t miss out on any important updates from our team!

How to prepare for a job interview at Cranleigh STEM, Sustainability & SHEQ Recruitment

✨Know Your Mass Spectrometry Inside Out

Make sure you brush up on your mass spectrometry knowledge, especially with Waters LC-MS systems. Be prepared to discuss specific techniques and how you've applied them in previous roles. This will show that you're not just familiar with the equipment but can also lead analytical strategies effectively.

✨Showcase Your Mentoring Skills

Since this role involves mentoring junior team members, think of examples where you've successfully guided others. Prepare to discuss your approach to training and how you ensure high standards in a collaborative environment. This will highlight your leadership capabilities.

✨Demonstrate Problem-Solving Prowess

Expect questions that assess your problem-solving skills, particularly in troubleshooting analytical methods. Have a few scenarios ready where you identified issues and implemented solutions, showcasing your proactive mindset and ability to perform under pressure.

✨Familiarise Yourself with ISO and GMP Standards

Since the role requires experience in ISO or GMP-regulated environments, be ready to discuss your understanding of these standards. Highlight any relevant experiences where you maintained compliance and ensured data integrity, as this will resonate well with the interviewers.

Senior LCMS Scientist
Cranleigh STEM, Sustainability & SHEQ Recruitment
Location: Portsmouth
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