At a Glance
- Tasks: Lead analytical workflows for nucleic acids and peptides using advanced techniques like HPLC.
- Company: Innovative biotech organisation focused on large molecule therapeutics.
- Benefits: Up to £50,000 salary, flexible hours, and generous leave.
- Why this job: Make a real impact in bioprocessing while mentoring the next generation of scientists.
- Qualifications: PhD or equivalent in Analytical Chemistry or related field with hands-on HPLC experience.
- Other info: Collaborative environment with excellent career growth and professional development opportunities.
The predicted salary is between 36000 - 60000 £ per year.
We’re partnering with an innovative scientific organisation to recruit a Senior Scientist with strong experience in downstream analytical processes, including HPLC and bioprocessing techniques, to join a high-performing team based in Southampton. This hands-on role offers the chance to support the development of modified nucleic acids and peptides, drive analytical method development, and contribute to the advancement of large molecule therapeutics in a collaborative, fast-paced environment.
About the Role
You’ll take the lead on analytical workflows for nucleic acids, peptides, and antibodies, ensuring high standards of quality, compliance, and scientific rigour. The role will include method development, instrument maintenance, and cross-functional collaboration across R&D and production teams. This position is ideal for a scientist who enjoys working across disciplines, mentoring junior colleagues, and staying at the forefront of analytical innovation.
Key Responsibilities
- Lead downstream analytical workflows using HPLC, UPLC, PAGE, flash chromatography, and related techniques
- Contribute to the purification and characterisation of large molecules, such as peptides and antibodies
- Support method development and continuous improvement in analytical approaches
- Collaborate with chemistry and production teams to support small molecule and oligonucleotide preparation
- Maintain, calibrate, and optimise analytical instrumentation in line with ISO and internal quality systems
- Mentor and support Associate Scientists and Lab Technicians
- Ensure accurate documentation and maintain data integrity across workflows
- Promote and uphold Health, Safety, and Environmental (HSE) standards
- Manage stock levels of analytical reagents and consumables
- Stay up to date on emerging trends in bioprocessing and analytical technologies
About You
We’re looking for a motivated and collaborative scientist with a solid grounding in downstream analytical techniques and a passion for quality science.
You’ll ideally have:
- A PhD (or equivalent experience) in Analytical Chemistry, Biochemistry, or a related field
- Strong hands-on experience in HPLC and bioprocessing within a biotechnology, pharmaceutical, or life sciences environment
- Knowledge of purification and characterisation methods for peptides, antibodies, or similar large molecules
- Experience with TFF or tangential flow filtration (advantageous)
- Familiarity with ISO or GMP-regulated environments
- Ability to lead technical projects and support team development
- Strong communication and problem-solving skills
- A flexible, proactive mindset with strong attention to detail
Salary & Benefits
Salary: Up to £50,000 depending on experience
Location: On-site in Southampton
Holidays: 25 days annual leave + 8 bank holidays
Pension: 6% employer contribution
Life Assurance: 4x salary
Additional Benefits Include:
- Flexible working hours
- Long service awards and recognition scheme
- Employee Assistance Programme with 24/7 remote GP access
- Annual flu vaccinations
- Cycle to work scheme and gym discounts
- Discounts and savings platform
- Professional membership reimbursement
- Referral incentives
- Social events and volunteering days
Locations
Senior Scientist in Hampshire, Portsmouth employer: Cranleigh STEM, Sustainability & SHEQ Recruitment
Contact Detail:
Cranleigh STEM, Sustainability & SHEQ Recruitment Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior Scientist in Hampshire, Portsmouth
✨Network Like a Pro
Get out there and connect with people in the industry! Attend conferences, workshops, or local meetups related to biotech and analytical chemistry. You never know who might have a lead on your dream job or can introduce you to someone who does.
✨Show Off Your Skills
When you get the chance to chat with potential employers, make sure to highlight your hands-on experience with HPLC and bioprocessing. Share specific examples of projects you've led or contributed to, especially those that showcase your problem-solving skills and attention to detail.
✨Be Ready for Technical Questions
Prepare yourself for some deep dives into your technical knowledge during interviews. Brush up on your understanding of purification methods and analytical techniques, and be ready to discuss how you've applied them in real-world scenarios. Confidence is key!
✨Apply Through Our Website
Don't forget to apply through our website for the best chance at landing that Senior Scientist role! We love seeing candidates who are proactive and engaged, so make sure your application stands out by tailoring it to the job description.
We think you need these skills to ace Senior Scientist in Hampshire, Portsmouth
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights your experience with downstream analytical processes, especially HPLC and bioprocessing. We want to see how your skills align with the role, so don’t be shy about showcasing relevant projects!
Craft a Compelling Cover Letter: Your cover letter is your chance to shine! Use it to explain why you’re passionate about large molecule therapeutics and how your background makes you a perfect fit for our team. Keep it engaging and personal!
Showcase Your Collaborative Spirit: Since this role involves cross-functional collaboration, highlight any experiences where you’ve worked with different teams. We love seeing how you can bring people together to achieve common goals!
Apply Through Our Website: We encourage you to apply directly through our website. It’s the best way for us to receive your application and ensures you don’t miss out on any important updates from our team!
How to prepare for a job interview at Cranleigh STEM, Sustainability & SHEQ Recruitment
✨Know Your Techniques
Make sure you brush up on your HPLC and bioprocessing techniques before the interview. Be ready to discuss specific projects where you've applied these methods, as well as any challenges you faced and how you overcame them.
✨Showcase Your Collaboration Skills
Since this role involves working with cross-functional teams, prepare examples of how you've successfully collaborated with others in the past. Highlight your ability to communicate effectively and mentor junior colleagues, as this will demonstrate your leadership potential.
✨Stay Current with Trends
Familiarise yourself with the latest trends in bioprocessing and analytical technologies. Being able to discuss recent advancements or innovations in the field will show your passion for quality science and your commitment to staying at the forefront of the industry.
✨Prepare for Technical Questions
Expect technical questions related to method development and instrument maintenance. Review relevant ISO and GMP regulations, and be prepared to explain how you ensure compliance and maintain data integrity in your work.