Medical Director, Oncology Clinical Development

Reporting to the Executive Medical Director, Clinical Development Lead (CDL), Oncology Clinical Development, the Medical Director will be responsible for clinical research activities that advance GSK’s oncology portfolio and for engaging in medical dialogues with relevant scientific and medical leaders to lead clinical data generation activities. This individual will also play a leading role in managing effective relationships with Key External Experts.

An on‑site office presence for a minimum of two days a week is required in one of GSK’s UK (London or Stevenage), US (PA or MA), Switzerland (Zug), Poland (Warsaw), or Canada (Mississauga) campuses.

Key Responsibilities

• Collaborate with physicians, scientists, regulatory professionals, biostatisticians, and executive staff in a complex matrix environment to develop and execute phase 1‑3 interventional clinical trials.
• Ensure high‑quality protocol development aligned with the Clinical Development Plan to effectively determine a medicine’s potential efficacy, safety profile, key areas of product differentiation, and value to patients in the shortest possible timeframe.
• Use medical expertise to contribute to the end‑to‑end (protocol concept to final study report) to ensure scientific integrity and timely delivery of clinical trials consistent with the clinical development strategy for regulatory approvals, reimbursable medicines, and successful lifecycle management.
• Interpret and summarize study results consistent with objectives to define safety, efficacy, pharmacokinetic/pharmacodynamic outcomes, and patient‑reported outcomes, and the applicability of data to the targeted patient population.
• Assume medical responsibility for clinical trials, including active participation in real‑time medical monitoring of studies, patient eligibility assessment, study design questions, and addressing urgent safety questions (with inclusion of Safety/PV as relevant).
• Assume responsibility for medical review of clinical trial data, directly as needed or via oversight of delegated medical review, and oversee blinded review of data packages intended for IDMCs.
• Review/monitor safety data in collaboration with pharmacovigilance group for active clinical studies.
• Participate in the authoring of clinical study reports and regulatory documents, and collaborate with colleagues in Regulatory Affairs, CMC, Toxicology, Research, and Pharmacology to respond to health authority and ethics committee queries.
• Collaborate with Principal Investigators in the evaluation and assessment of publications (abstracts, posters, manuscripts) associated with clinical data.
• Network extensively to develop long‑term strategic partnerships with thought leaders both internally and externally, in support of GSK’s vision.
• Understand biological mechanisms, clinical strategy, and scientific interpretation of disease and target‑based literature.
• Serve as a core member of the Clinical Matrix Team for one or more assets in development.
• Represent Clinical Development on disease area strategy, integrated evidence, and medical affairs strategy teams.
• Participate in Oncology Clinical Development‑wide initiatives and workstreams as appropriate.

Basic Qualifications

• Medical degree with board certification/eligibility or registration qualifications in medical oncology, hematology, hematology/oncology, Gynecologic oncology, general surgery, or internal medicine.
• Oncology or gynecologic oncology experience in the pharmaceutical/biotechnology industry, clinical academic medicine, or clinical medical practice settings.
• Oncology clinical drug development process experience in the conduct/participation of clinical trials (investigator‑initiated, company‑sponsored, or cooperative group trials).

Preferred Qualifications

• Oncology clinical research and drug development experience focused on GYN cancer, Breast cancer, or other solid tumors.
• Regulatory experience to support registration and GCP principles.
• Robust knowledge of disease‑specific research priorities, public health needs, competitor landscape, clinical practice trends, and treatment guideline evolution.

Salary ranges are location dependent: in the U.S. the annual base salary for this position ranges $222,750 to $371,250; in Poland the annual base salary ranges from PLN 455,250 to PLN 758,750 gross. The position offers an annual bonus and eligibility to participate in a share‑based long‑term incentive program, as well as health care and other insurance benefits, retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information, military service or any basis prohibited under federal, state or local law.