UK date and time: 24-September-:03
Research Facility Scientist (Transgenics and Genome Engineering)
Radcliffe Department of Medicine, MRC Weatherall Institute of Molecular Medicine, Genome Engineering Services Facility, John Radcliffe Hospital, Headington, Oxford, OX3 9DS
An underfill at Grade 6 will be considered with amended duties and a 12-month development plan and mentoring put in place for the successful candidate.
This vacancy is being re-advertised. Previous applicants need not apply
We have an exciting opportunity to join the Institute as a Research Facility Scientist within the MRC WIMM Genome Engineering, Transgenics and Virus Production Facility.
The MRC WIMM Genome Engineering, Transgenics and Virus Production Facility is a specialist core Facility providing expertise in the design, generation and validation of genetically modified model systems. Working with research groups across the Institute, we combine molecular and cellular biology with state-of-the-art genome engineering and transgenic technologies to produce high-quality, validated reagents and models that enable cutting-edge biomedical research.
Our work encompasses CRISPR-based genome engineering, generation of genetically modified cell lines and mouse models, molecular validation, mouse embryonic stem cell technologies, cryopreservation and rederivation. We work closely with researchers from initial experimental design through to delivery of validated, ready-to-use models.
About the Role
As a Research Facility Scientist, you will join an experienced specialist team and contribute to all aspects of the design, generation and validation of genetically modified models.
You will work closely with researchers to understand their experimental requirements and help develop appropriate genome-engineering strategies. You will take responsibility for technically complex laboratory workflows, from molecular design and reagent generation through to genome editing, screening and molecular validation.
An important part of the role will be working collaboratively with Facility users. You will discuss project requirements with researchers, provide technical advice and communicate experimental progress and results clearly. You will manage multiple projects at different stages of delivery and work closely with other members of the facility to ensure an efficient and high-quality service.
About You
You will hold a degree in Biological Sciences, Molecular Biology, Genetics or a closely related discipline and have substantial relevant laboratory experience. Experience in core molecular biology techniques, including significant experience in CRISPR/Cas9 technology and cell culture techniques including iPSC, mESC and other cell lines, will be essential.
You will be confident in planning and carrying out technically complex laboratory work and will have a systematic approach to experimental design, troubleshooting and interpretation of results. You will be able to work independently, exercise sound scientific judgement and manage multiple projects and competing priorities while maintaining consistently
high standards of accuracy and reproducibility.
Excellent interpersonal and communication skills and being comfortable working collaboratively with researchers from a wide range of scientific backgrounds will be required. You will be able to explain technical information clearly, discuss experimental options and limitations, and provide constructive scientific advice.
You will be proactive, organised and collaborative, with a strong commitment to delivering a high-quality research service.
Contract Type
This is a full-time (37.5 hours per week) fixed-term position for 3 years.
The closing date for this position is 12 noon on Wednesday 14 October 2026. Interviews will be held on Tuesday 3 November 2026.
Research Facility Scientist (Transgenics and Genome Engineering) in Oxford employer: Corehr
As a leading research institution, we offer an exceptional environment for postdoctoral researchers to thrive, particularly in the vibrant city of Liverpool. Our commitment to collaboration across prestigious universities fosters a dynamic work culture that prioritises innovation and inclusivity, while our hybrid working model supports a healthy work-life balance. With ample opportunities for professional growth and a focus on diversity, we are dedicated to creating a meaningful and rewarding experience for all employees.
