At a Glance
- Tasks: Lead experimental work on innovative gene therapies for neurological diseases.
- Company: Join the prestigious University of Oxford's Cader Lab at the Kavli Institute.
- Benefits: Competitive salary, collaborative environment, and access to cutting-edge research.
- Other info: Full-time position with opportunities for collaboration across Europe.
- Why this job: Make a real impact in gene therapy and advance your scientific career.
- Qualifications: Postdoctoral experience in stem-cell biology or neurovascular physiology preferred.
The predicted salary is between 39424 - 47779 £ per year.
The postholder will join the Cader Lab at the Kavli Institute for Nanoscience Discovery, University of Oxford, to lead experimental work for one of the key workpackages of the EU Innovation Council SECURE project, a major multi-partner programme developing self adaptive gene therapies for neurological disease.
This will involve:
- Producing a single nuclei atlas of the substantia nigra
- Developing and applying advanced human iPSC-derived blood–brain barrier (BBB) models to evaluate next‑generation CNS‑targeted viral vectors
The successful candidate will use models to assess vector transcytosis and tropism in both healthy and disease contexts. The work will generate human‑relevant data on BBB permeability, receptor expression and transcriptomic signatures that will directly inform AI‑driven viral vector design within the SECURE consortium.
This is an exceptional opportunity for a motivated postdoctoral scientist to contribute to a transformative gene therapy platform and to work at the interface of stem‑cell biology, neurovascular physiology and translational therapeutics. The postholder will benefit from the Cader Lab’s extensive expertise in iPSC modelling, neurovascular systems, and multi‑omics profiling, and will collaborate closely with academic and industrial partners across Europe.
The post is full time for a fixed term until 30th January 2029 in the first instance. Only applications received before 12.00 midday on Friday 26th June will be considered. Interviews will be held as soon as possible thereafter.
Salary (£): £39,424 – £47,779 per annum. A less experienced candidate may be appointed at Research Grade 6 (£35,681 - £41,636 per annum), with a commensurate adjustment in either the essential criteria, responsibilities or duties.
Postdoctoral Researcher in Human Neurovascular Cell Models in Oxford employer: Corehr
The Nuffield Department of Clinical Neurosciences at the University of Oxford offers an exceptional work environment for postdoctoral researchers, fostering a culture of innovation and collaboration. With access to cutting-edge resources and a strong emphasis on employee development, you will have the opportunity to contribute to groundbreaking research in gene therapy while working alongside leading experts in the field. Located in the historic city of Oxford, this role not only promises meaningful scientific contributions but also a vibrant community and rich cultural experiences.
StudySmarter Expert Advice🤫
We think this is how you could land Postdoctoral Researcher in Human Neurovascular Cell Models in Oxford
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We think you need these skills to ace Postdoctoral Researcher in Human Neurovascular Cell Models in Oxford
Some tips for your application 🫡
Show Off Your Lab Skills:In the biotechnology field, it's super important to highlight your lab experience in your CV. Be sure to mention specific techniques or instruments you've mastered (think PCR, gel electrophoresis, etc.) and any relevant projects you've worked on. This will show Corehr that you have the hands-on skills they need.
Tailor Your Technical Skills:Make sure to emphasise your technical skills, especially those relevant to the biotechnology sector. Include any software tools or programming languages you've used, like R or Python for data analysis, which could be key for this role at Corehr.
Craft a Compelling Cover Letter:Since this is a full-time role, your cover letter should reflect not only your passion for biotechnology but also your long-term career ambitions. Share why you're excited about the work that Corehr does and how you envision contributing to their goals. This shows that you’re not just looking for any job, but you're genuinely invested in this opportunity.
Include Your Papers and Projects:If you've published any papers or contributed to significant projects, mention them! These documents can boost your application and provide tangible evidence of your expertise in the biotechnology field. Don’t forget to link to any relevant publications or project summaries—this can set you apart from other candidates.
How to prepare for a job interview at Corehr
✨Brush Up on Lab Techniques
Since you're eyeing a full-time gig in biotechnology, make sure you're well-versed in the lab techniques relevant to the role. Be ready to talk about PCR, CRISPR, or any specific methods mentioned in the job description at Corehr. You might even be asked to demonstrate your understanding of these processes.
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Get comfortable with bioinformatics tools that are commonly used in the industry, like BLAST or Bioconductor. These are key in biotechnology, and having hands-on experience or at least familiarity can set you apart. Prepare to discuss any relevant projects you've worked on, especially if they involved data analysis or genomic research.
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