Clinical Scientist, Clinical Sciences (Fixed-Term Contract) in London

Compass Pathways plc (Nasdaq: CMPS) is a biotechnology company dedicated to accelerating patient access to evidence-based innovation in mental health. The Company is headquartered in London, UK, with offices in New York City in the US. We focus on developing novel treatments that have the potential to improve the lives of those who are suffering with mental health conditions and who are not helped by current treatments. We are pioneering a new paradigm for treating mental health conditions focused on rapid and durable responses through the development of our investigational COMP360 synthetic psilocybin treatment, potentially a first in class treatment. COMP360 has Breakthrough Therapy designation from the US Food and Drug Administration (FDA) and has received Innovative Licensing and Access Pathway (ILAP) designation in the UK for treatment-resistant depression (TRD) due to the pressing unmet need in this area. We are currently in phase 3 for TRD, have completed phase 2 studies for both post-traumatic stress disorder (PTSD) and anorexia nervosa and are planning a further late-stage study in PTSD. We envision a world where mental health means not just the absence of illness but the ability to thrive.

The Clinical Scientist, Clinical Sciences will assist with the clinical development and scientific oversight of late stage clinical trials. The role partners closely with Clinical Operations, Statistics, Data Management, Clinical Safety, Regulatory Sciences, and HEOR to deliver high-quality studies, enabling timely, compliant, and insight-driven decision making.

Location: Hybrid in our Soho London office or remote in the United Kingdom.

Reports to: Principal Clinical Scientist, Clinical Sciences.

Duration: Until the end of 2026.

Roles and responsibilities (Include but are not limited to):

• Serve as the primary “point person” for assigned clinical research duties.
• Support scientific oversight during study execution, supporting database design, medical monitoring, site initiation visits, protocol deviation review and clarification, and interpretation of clinical signals across programs.
• Author and review participant-facing documents such as the informed consent form and advertisement material.
• Support development of study conduct and statistical analysis plans; review data to ensure quality of study conduct and data collection.
• Accountable for compliance with ethical and scientific standards, regulatory requirements, and the Compass Quality Management System, ensuring participant safety, data integrity, and accuracy throughout the trial process.
• Contribute to cross-functional readiness for key milestones (database lock, regulatory documents), establishing operating rhythms and documentation standards consistent with Compass values and governance.
• Champion patient-centric design, incorporating feasibility data, KOL feedback, and ethical considerations into procedures, visit schedules, and burden-reduction strategies.

Candidate Profile:

• A PhD or PharmD is highly preferred but not required. MS candidates with equivalent experience also will be considered.
• PhD or post-doctoral training should be in neuroscience, pharmacology, psychology, psychiatry, or other relevant biomedical science.
• PharmD graduates should have training in research methods or postdoctoral research experience as above.
• MS graduates should demonstrate scientific accomplishment comparable to that acquired in doctoral training as above.
• Relevant experience in conducting and designing clinical research in neuroscience, pharmacology, psychiatry, or neurology.
• Proven capability to translate biology and patient insights into clear study objectives, endpoints, and operationally feasible designs.
• Strong analytical and statistical skills, experience authoring scientific documents, and well-developed communication skills appropriate to varying target audiences.
• Excellent scientific writing, data interpretation, and communication skills, with a track record of high-quality clinical documents and timely milestone delivery.
• Mission-aligned, inclusive contributor who reflects Compass values and a wellbeing-first, stigma free culture.

Benefits & Compensation: For an overview of our benefits package and compensation information, please visit "Working at Compass".

Equal opportunities: Reasonable accommodation. We are committed to building a workplace where everyone’s wellbeing matters. If you need reasonable accommodation during the interview process to be at your best, please let our recruiting team know.

We are proud of our commitment to diversity and equality (pursuant to the Equality Act 2010). We do not discriminate based upon race, religion or belief, colour, nationality, ethnic or national origin, gender, pregnancy or maternity, marital or civil partner status, sexual orientation, gender reassignment, age or disability.

Unfortunately, we cannot sponsor employment visas and can only accept applications if you have employment rights in the country to which you are applying.

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