Clinical Rater in Sheffield

Clerkenwell Health is a pioneering mental health research organisation specialising in psychedelic-assisted therapy. We conduct innovative, scientifically grounded clinical trials through our integrated Contract Research Organisation (CRO), broad Clinical Research Facility (CRF) network, and Therapist Training Programme. We have also expanded our focus to the treatment of central nervous system (CNS) disorders, in addition to complex mental health conditions.

We’re looking for a Clinical Trials Psychologist/Rater who will support the delivery of Phase 1–3 clinical trials, to ensure high-quality patient care and adherence to Sponsor requirements, ICH-GCP, and relevant regulatory standards. The role is central to studies involving psychedelic compounds, mental health, neuropsychiatric disorders, and future therapeutic areas, with a strong focus on the timely and ethical conduct of clinical research.

This position combines hands-on clinical research responsibilities with direct participant interaction, including validated psychiatric and neurological assessments, supporting dosing sessions, and collecting high-quality clinical data. You will provide leadership within the research team, collaborate cross-functionally, and maintain the highest standards of participant safety, protocol compliance, and data integrity in complex and sensitive research environments.

Key responsibilities include:

• Conduct structured and semi-structured psychiatric and neuropsychiatric assessments, including but not limited to: MADRS, MINI, CGI-S / CGI-I & HAM-A.
• Conduct participant screening, eligibility assessments, baseline evaluations and outcome measurements following study protocols, regulatory approvals, and GCP guidelines.
• Identify, document and escalate adverse events. Provide session oversight, including real-time clinical decision-making and adverse event management.
• If appropriate, taking informed consent, performing concomitant medication assessment, physical examinations, medical history, etc.
• Where possible, support dosing sessions as a dosing session monitor (lead or assistant DSM or facilitator during clinical sessions, ensuring participant safety and adherence to the protocol).
• Act as a key site/scientific representative during sponsor reviews, CRO oversight, audits, and regulatory inspections (e.g., MHRA, FDA).
• Ensure clinical data quality, accurate source documentation standards per ALCOA++ principle and endpoint reliability.
• Support staff induction, onboarding, and ongoing training in clinical assessments, study procedures, and GCP compliance.

Essential Experience & Qualifications:

• Advanced degree or equivalent experience in Psychology, Neuroscience, Pharmacology, Biomedical Science, Medicine or related field.
• Significant experience delivering interventional CNS, psychedelic, psychopharmacology or mental health clinical trials in commercial or regulated environments.
• Demonstrated competence in psychiatric assessments (MADRS, MINI, CGI, HAM-A).
• Strong working knowledge of GCP and relevant regulatory guidelines.

At Clerkenwell Health, our core values are Compassion, Collaboration, Innovation, and Integrity. If you’re excited about contributing to pioneering psychedelic and mental health research, and you’re passionate about delivering safe, ethical, and evidence-based therapy, we’d love to hear from you.