At a Glance
- Tasks: Lead psychedelic clinical trials, ensuring compliance and participant care.
- Company: Clerkenwell Health is a pioneering Research Organisation focused on mental health and psychedelic drug development.
- Benefits: Enjoy a collaborative work environment and the chance to make a real impact in mental health research.
- Other info: Weekly travel to Doncaster is necessary; strong communication skills are essential.
- Why this job: Join a team dedicated to innovation and compassion in improving mental health outcomes.
- Qualifications: Medical degree, GMC registration, and experience as a Principal Investigator required.
The predicted salary is between 43200 - 72000 £ per year.
Job Description
Who are we?
Clerkenwell Health is an innovative and leading Research Organisation specialising in the delivery of scientifically grounded Clinical Trials using its collaborative Contract Research Organisation, extensive Site Network and leading Therapy Development Programme. We focus on supporting Mental Health and CNS research, with particular expertise in psychedelic drug development.
The role
We are seeking an experienced Principal Investigator (PI) to lead the medical oversight and delivery of psychedelic-assisted psychotherapy clinical trials. The post holder will play a critical leadership role in ensuring the highest standards of clinical and research integrity, regulatory compliance, and participant care throughout the study lifecycle.
What will the role entail?
- Serve as the Principal Investigator on psychedelic clinical trials, fulfilling all responsibilities outlined under ICH-GCP, including governance, oversight, pharmacovigilance, and reporting.
- Promote and ensure adherence to Good Clinical Practice (GCP) and all protocol requirements across trial operations.
- Oversee the medical and psychiatric evaluation of participants at screening, dosing, and follow-up stages; manage referrals to GP or specialist services as needed.
- Ensure full protocol compliance during trial procedures; identify and document any deviations appropriately.
- Accurately report serious adverse events (SAEs) and adverse events (AEs) to the trial sponsor and Chief Investigator.
- Supervise and mentor clinical staff involved in study-specific assessments and procedures.
- Provide clinical leadership, training, and ongoing mentorship to trial staff to uphold GCP and protocol standards.
- Foster a positive and collaborative team environment within Clerkenwell Health and with external stakeholders.
- Ensure accurate and complete documentation in source notes and clinical trial case report forms (CRFs).
- Oversee the use, storage, dispensing, and accountability of Investigational Medicinal Products (IMP) and non-IMPs.
- Monitor and review the completion of psychometric and structured interview assessments conducted with trial participants.
- Maintain current knowledge of psychedelic-assisted therapies, relevant clinical protocols, and therapeutic innovations.
What will you need?
- To be able to travel to Doncaster at least once a week
- Medical degree (e.g., MBBS, MD)
- GMC full registration with licence to practise
- MRCPsych, MRCP, or equivalent medical college membership
- Previous Experience as a Principal Investigator (PI)
- Experience in mental health or CNS therapeutic areas would be advantageous
- In-depth knowledge of clinical research regulations (FDA, EMA, MHRA), ICH-GCP guidelines, and local/international laws
- Excellent communication and interpersonal skills for liaising with sponsors, CROs, and site teams
- Familiarity with ethical research conduct, informed consent, and IRB/Ethics Committee review processes
- Sound risk management and safety practices
- Experience with rating tools such as MINI, CAPS-5, and C-SSRS
What will the process be?
An initial screening call with the recruiter followed by a 2 stage interview process over Teams.
Is This the Role for You?
At Clerkenwell Health, our core values are Compassion, Collaboration, Innovation, and Integrity. If you're passionate about improving mental health outcomes through research and ready to take a lead role in pioneering psychedelic-assisted therapies - we’d love to hear from you.
Principal Investigator (PI) in Doncaster employer: Clerkenwell Health
Clerkenwell Health is an exceptional employer, offering a dynamic work environment that prioritises compassion, collaboration, and innovation in the field of mental health research. As a Principal Investigator, you will have the opportunity to lead groundbreaking clinical trials while benefiting from a supportive culture that fosters professional growth and mentorship. Located in Doncaster, our team thrives on collaboration with external stakeholders, ensuring that you are at the forefront of pioneering psychedelic-assisted therapies that can make a meaningful impact on mental health outcomes.
StudySmarter Expert Advice🤫
We think this is how you could land Principal Investigator (PI) in Doncaster
✨Get Involved in Research Communities
Dive headfirst into the scientific research world by joining relevant communities and forums. Engage in discussions, share your insights, and even attend conferences or seminars in your field. This not only boosts your visibility but can also lead to potential job opportunities—don't forget to connect with like-minded folks!
✨Show Off Your Research Projects
Have you worked on any cool research projects? Make it easy for potential employers to see your work by creating a portfolio or a personal website. This way, when you apply for roles like the one at Clerkenwell Health, you can point them to your projects and publications, showcasing your expertise directly.
✨Utilise Professional Networks
Networking is key in scientific research. Join professional bodies or organisations related to your field. They often have job boards and resources tailored for job seekers. Make connections with professionals who may know about openings or can give you tips on landing a full-time position.
✨Keep Your Eyes on Openings & Apply Directly
Don’t just rely on job boards! Keep an eye on the careers section of the websites of companies like Clerkenwell Health. Apply directly through their website because sometimes they post jobs there before anywhere else. Plus, it shows your proactive approach!
We think you need these skills to ace Principal Investigator (PI) in Doncaster
Some tips for your application 🫡
Highlight Your Research Experience:When applying for a full-time role in scientific research, make sure to emphasise your research experience prominently in your CV. Share specific projects you’ve worked on, the methodologies you used, and any significant findings. If you’ve published papers or presented at conferences, definitely include that too – it shows you’re on it in the academic world!
Tailor Your Cover Letter to the Research Area:Your cover letter should reflect your passion for the specific area of research at Clerkenwell Health. Mention relevant experiences that align with the organisation’s goals or projects. This shows that you’ve done your homework and are genuinely interested in the position – plus, it helps us see how you’d fit into the team dynamics.
Showcase Your Data Analysis Skills:In scientific research, data analysis skills are a big deal! Make sure to detail any relevant analytical tools or software you’re familiar with, like R, Python, or statistical packages. Employers are keen to know you can handle the data-heavy elements of the role, so add specific examples where you’ve used these skills effectively.
Discuss Your Future Research Goals:In your motivation section, it’s a great idea to talk about your future research goals and how they align with the work being done at Clerkenwell Health. This shows that you’re not just looking for any job, but rather a chance to contribute meaningfully to the field. We love to see applicants who are forward-thinking and enthusiastic about their research journey!
How to prepare for a job interview at Clerkenwell Health
✨Showcase Your Research Skills
In scientific research, it’s crucial to demonstrate your ability to design and conduct experiments. Come armed with examples of past projects where you've developed hypotheses, collected data, and analysed results. Be ready to discuss any specific methodologies or tools you’ve used, like PCR techniques or statistical software.
✨Prepare for Technical Questions
Expect some technical questions specific to your field. Make sure you're up to speed with recent advancements in scientific research related to the role at Clerkenwell Health. Brush up on concepts relevant to their projects and be prepared to discuss how you would approach a specific research problem or challenge they might face.
✨Know Your Publications
If you've authored or co-authored any papers, be prepared to discuss them! Highlighting your contributions to published research can really set you apart. It shows not only your expertise but also your ability to communicate complex ideas clearly, which is key in scientific research roles.
✨Exhibit Your Team Spirit
In full-time roles, collaboration is often at the heart of scientific research. Prepare examples that show how you've successfully worked in teams, dealt with conflicts, or contributed to group projects. We want to know how you can work effectively with the team at Clerkenwell Health to drive research projects forward.
