At a Glance
- Tasks: Conduct cutting-edge research in Computational Structural Biology and develop innovative computational methods.
- Company: Join the University of Birmingham, a leader in research and diversity.
- Benefits: Competitive salary, financial support for visa fees, and opportunities for professional growth.
- Other info: Collaborate with international teams and contribute to groundbreaking research.
- Why this job: Make a real impact in understanding biomolecular structures and dynamics at atomic resolution.
- Qualifications: PhD (or near completion) in relevant fields and expertise in molecular dynamics simulations.
The predicted salary is between 36636 - 46049 £ per year.
Salary: Full time starting salary is normally in the range £36,636 to £46,049, with potential progression once in post to £48,822
Applications are welcomed from candidates in Europe and other overseas countries.
Financial support for visa application fees is available, subject to eligibility and organisational policy.
A Research Fellow position is available in Computational Structural Biology within the group of Prof.
Teresa Carlomagno.
The group investigates the structural and functional mechanisms of proteins, intrinsically disordered proteins, membrane proteins, nucleic acids, and their complexes using an integrative structural biology approach.
Combining experimental and computational methods, the laboratory aims to understand biomolecular structure, dynamics, and function at atomic resolution.
The post holder will apply advanced computational approaches to study membrane proteins, protein-ligand complexes, and biologically relevant macromolecular assemblies, focusing on molecular recognition, conformational dynamics, allosteric regulation, and ligand binding.
Candidates should have strong expertise in molecular dynamics simulations and enhanced-sampling methodologies such as metadynamics, accelerated molecular dynamics, or related approaches, together with advanced simulation data analysis including dimensionality reduction, conformational landscape analysis, and identification of metastable states.
Experience in multiscale modelling is highly desirable.
The successful candidate will integrate computational approaches with experimental data from X-ray crystallography, NMR spectroscopy, cryo-electron microscopy, mass spectrometry, and biophysical measurements, while developing novel computational methods and modelling strategies.
Main Duties
- Develop research objectives and proposals in Computational Structural Biology.
- Generate, analyse, and interpret computational data alongside structural biology, biochemical, and biophysical data.
- Apply advanced molecular dynamics techniques to investigate membrane proteins, protein‑ligand complexes, and macromolecular assemblies.
- Integrate computational models with experimental structural and biochemical data.
- Collect research data through experimentation and literature reviews.
- Develop new computational approaches, workflows, methodologies, models, and techniques.
- Disseminate findings through seminars, conferences, posters, publications, and manuscript preparation.
- Supervise students and provide guidance to Ph D researchers.
- Contribute to research funding applications.
Person Specification
- Ph D (or near completion) in Computational Structural Biology, Biophysics, Structural Biology, Computational Chemistry, Biochemistry, Physics, or a related field.
- Proficiency in computational studies of biomolecular systems.
- Expertise in the structural and functional investigation of membrane proteins and/or protein‑ligand complexes.
- Experience with molecular modelling, structural analysis, computational biophysics, or related computational methodologies.
- Experience in integrating computational approaches with experimental structural biology data.
- Practical biochemical laboratory experience and/or nucleic acid handling is desirable.
- Demonstrated ability to develop and apply new computational methods and research approaches.
- Strong quantitative, analytical, problem‑solving, written, and oral communication skills.
- Experience publishing in peer‑reviewed journals.
- Ability to manage resources effectively, work independently, and collaborate within multidisciplinary international teams.
- Understanding of research management, administration, planning, and organisation.
- Commitment to the Equality Act 2010 principles and willingness to work in a competitive international research environment.
- Informal enquiries to Teresa Carlomagno, email: t. carlomagno@bham. ac. uk
- Valuing excellence, sustaining investment
We value diversity and inclusion at the University of Birmingham and welcome applications from all sections of the community and are open to discussions around all forms of flexible working
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Research Fellow in Computational Structural Biology in Birmingham employer: Chemistry Guide
The University of Birmingham is an exceptional employer, offering a dynamic and inclusive work culture that fosters innovation and collaboration in the field of Computational Structural Biology. With competitive salaries, opportunities for professional development, and a commitment to diversity, employees are encouraged to grow their skills while contributing to groundbreaking research in a supportive environment. Located in a vibrant city, the university provides access to a wealth of resources and a strong network of international researchers, making it an ideal place for those seeking meaningful and rewarding careers.
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We think you need these skills to ace Research Fellow in Computational Structural Biology in Birmingham
Some tips for your application 🫡
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