At a Glance
- Tasks: Lead bioanalytical projects and develop innovative methods for drug discovery.
- Company: Join Charles River, a leader in drug development with a global impact.
- Benefits: Enjoy competitive pay, health perks, flexible work options, and professional growth.
- Other info: Be part of a diverse team dedicated to improving lives through science.
- Why this job: Make a real difference in healthcare while advancing your career in a dynamic environment.
- Qualifications: Experience in bioanalysis and LC-MS; strong problem-solving and communication skills.
The predicted salary is between 50000 - 65000 £ per year.
For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.
Are you already an experienced bioanalyst looking for your next role? Do you have refined skills in LC-MS maintenance and troubleshooting? Are you proficient in bespoke method development within small molecules? If you answered yes to any, or all of those questions then good news, our Cambridge site has a vacancy for a Senior Technical Specialist - DMPK!
A highly experienced lab and office based bioanalyst providing wide in-depth scientific and technical expertise to both multidisciplinary integrated Drug Discovery projects and standalone DMPK projects. This role combines hands-on bioanalytical expertise with project leadership, mentoring, and continuous improvement responsibilities to support small and large molecule drug discovery programmes. Offering you opportunities across varied DMPK and broader scientific projects and development across multiple scientific and technical areas.
Main Tasks:
- Developing, optimising and executing the bioanalysis of samples from in vivo DMPK studies for small and large molecule drug discovery projects in an early discovery setting.
- Extensive knowledge of modern UPLC-MS systems and software including chromatographic method development.
- Demonstrated ability to perform routine and complex troubleshooting, maintenance, and optimisation of mass spectrometry and LC equipment, ensuring reliable operation and rapid resolution of technical issues.
- Experience in the analysis of different sample types such as plasma, blood, brain, lung, bile, faeces, urine.
- Demonstrated experience of pharmacokinetic parameter determination and an understanding of the underlying principles.
- Comprehensive troubleshooting and problem-solving skills using both technical and scientific expertise.
- Strong organisation and time management skills alongside an inbuilt flexibility to adapt to change.
- Excellent communication skills and be an effective team player; these will be essential to successful execution of projects whilst working in a matrix and multi-skilled environment.
- Lead scientific and technical projects, ensuring delivery of high-quality data to agreed timelines.
- Drive innovation through the development of novel assays, protocols and analytical approaches.
- Mentor, coach and develop colleagues, acting as a technical role model and recognised subject matter expert.
Qualifications and Experience:
- BSc or equivalent in relevant scientific area.
- Industry experience in pharma, biotech or other commercial organisations.
- Expert user of Mass Spectrometry instrumentation.
- Experience in the bioanalytical method development of challenging analytes, in complex matrices.
- Accurate & diligent experimental planning, execution and troubleshooting.
- Good communication skills (verbal/written) internally and externally.
- Excellent team player.
- Positive ‘can do’ attitude.
- Creative problem solving.
- Ability to plan & execute work independently.
- Project management.
- Strong organisation and time management skills alongside an inbuilt flexibility to adapt to change.
- Experience of guiding/mentoring junior colleagues.
- LC-MS/MS maintenance and troubleshooting.
- Bespoke method development for small molecules.
What We Offer You:
Charles River Laboratories provides a competitive benefits package starting from day one of employment.
- Financial & Retirement: Highly competitive pension contribution packages, group life assurance, bonus and group income protection.
- Health & Wellness: Private medical insurance (often extending to family members), private dental care, 24/7 remote GP access, and critical illness cover.
- Work-Life Balance: Generous parental leave policies, flexible working arrangements depending on business needs, and the option to buy or sell annual leave.
- Additional Perks: Cycle to work scheme, electric car scheme, paid professional development and training opportunities, and a dedicated employee assistance programme for well-being support.
About Discovery:
Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 350 patents and 80 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.
About Charles River:
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.
At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 86% of the drugs approved by the FDA in 2021.
At Charles River Laboratories, we recognize and recruit all talent. We are a company committed to the principle of diversity and inclusion and work daily in this direction.
Senior Technical Specialist - DMPK in Essex employer: Charles River
At Charles River, we pride ourselves on being an exceptional employer, fostering a collaborative and innovative work culture that empowers our employees to make a meaningful impact in drug discovery. Located in Portishead, our team enjoys a comprehensive benefits package, including a generous bonus scheme and non-contributory pension, alongside ample opportunities for professional development and growth. Join us to lead scientific excellence while mentoring the next generation of scientists in a supportive environment dedicated to health and well-being.
StudySmarter Expert Advice🤫
We think this is how you could land Senior Technical Specialist - DMPK in Essex
✨Get Involved in Local Research Communities
Tap into local biotechnology meetups and research forums. These are great places to mingle with industry professionals, share your passion, and even discover unadvertised job openings. It's all about getting your face known in the field!
✨Leverage University Alumni Networks
If you're a recent grad, don’t underestimate the power of your university’s alumni network! Reach out to alumni working in biotechnology to gather tips about job openings at companies like Charles River. You'd be surprised how willing people are to help out a fellow grad!
✨Show Off Your Projects
Curate a portfolio showcasing any research projects or internships you've completed in biotechnology. This tangible evidence of your skills can really impress employers when you chat with them at networking events or interviews. It's about making that killer first impression!
✨Stay Up-to-Date with Industry Trends
Biotech is a fast-paced field, so keeping yourself updated with the latest advancements is crucial. Attend industry conferences, webinars, or workshops to broaden your knowledge and meet potential employers. Plus, it’ll give you fantastic talking points for your interviews at places like Charles River!
We think you need these skills to ace Senior Technical Specialist - DMPK in Essex
Some tips for your application 🫡
Show Off Your Lab Skills:In the biotechnology field, it's super important to highlight your lab experience in your CV. Be sure to mention specific techniques or instruments you've mastered (think PCR, gel electrophoresis, etc.) and any relevant projects you've worked on. This will show Charles River that you have the hands-on skills they need.
Tailor Your Technical Skills:Make sure to emphasise your technical skills, especially those relevant to the biotechnology sector. Include any software tools or programming languages you've used, like R or Python for data analysis, which could be key for this role at Charles River.
Craft a Compelling Cover Letter:Since this is a full-time role, your cover letter should reflect not only your passion for biotechnology but also your long-term career ambitions. Share why you're excited about the work that Charles River does and how you envision contributing to their goals. This shows that you’re not just looking for any job, but you're genuinely invested in this opportunity.
Include Your Papers and Projects:If you've published any papers or contributed to significant projects, mention them! These documents can boost your application and provide tangible evidence of your expertise in the biotechnology field. Don’t forget to link to any relevant publications or project summaries—this can set you apart from other candidates.
How to prepare for a job interview at Charles River
✨Brush Up on Lab Techniques
Since you're eyeing a full-time gig in biotechnology, make sure you're well-versed in the lab techniques relevant to the role. Be ready to talk about PCR, CRISPR, or any specific methods mentioned in the job description at Charles River. You might even be asked to demonstrate your understanding of these processes.
✨Know Your Bioinformatics Tools
Get comfortable with bioinformatics tools that are commonly used in the industry, like BLAST or Bioconductor. These are key in biotechnology, and having hands-on experience or at least familiarity can set you apart. Prepare to discuss any relevant projects you've worked on, especially if they involved data analysis or genomic research.
✨Show Your Teamwork Skills
Biotech often involves collaboration across multiple disciplines. Be ready to share stories that highlight your teamwork and communication skills, especially in research projects. Think about working with different teams at university or any internships – this is where you can show how well you fit into Charles River's culture.
✨Research Recent Biotech Innovations
Stay updated on the latest trends and breakthroughs in biotechnology. Knowing what's happening in the field can help you engage in more meaningful discussions during your interview. Bring up recent articles or advancements that excite you, especially those related to the work being done at Charles River. This shows your passion for the industry!
