Research Scientist - Biotechnology in City of London

A Clinical Scientist with a strong focus on clinical data review to support the interpretation and quality oversight of study data across our clinical development programmes. The successful candidate will review patient-level and aggregate clinical data, identify medically relevant trends and discrepancies, support safety and efficacy interpretation, and contribute to key study deliverables. This role requires strong scientific judgement, attention to detail, and the ability to collaborate closely with clinical, statistical, operational, and regulatory colleagues.

The Clinical Scientist will review clinical, safety, and efficacy data to identify trends, outliers, inconsistencies, and medically relevant findings. They will work closely with Clinical Development, Clinical Operations, Biometrics, Medical, Pharmacovigilance, Regulatory Affairs, and external vendors to support high-quality data review and interpretation.

• Conduct ongoing medical and scientific review of clinical trial data, including patient profiles, laboratory data, adverse events, concomitant medications, eligibility criteria, protocol deviations, and efficacy endpoints.
• Identify clinically significant trends, data discrepancies, safety signals, and potential issues requiring follow-up.
• Support the preparation and review of data listings, tables, figures, dashboards, and patient narratives.
• Contribute to medical data review plans, data cleaning strategies, query generation, and query resolution.
• Review clinical database outputs to ensure consistency with protocol objectives, statistical analysis plans, and medical expectations.
• Collaborate with cross-functional teams to support interim analyses, data cuts, dose-escalation reviews, safety review meetings, and database lock activities.
• Participate in review of protocol amendments, informed consent forms, case report forms, and data collection tools to ensure appropriate medical and scientific content.
• Execute day-to-day responsibilities of the role, ensuring quality, accuracy, and timeliness.
• Contribute to problem-solving and decision-making processes with an objective, data-driven approach.

The ideal candidate will have a strong scientific or medical background with experience reviewing clinical trial data in a biotechnology, pharmaceutical, CRO, or academic clinical research setting.

• Degree in life sciences, medicine, pharmacy, or a related discipline; MD, PhD, PharmD, or MSc preferred.
• Strong understanding of clinical trial conduct, GCP, protocol requirements, medical terminology, and clinical data standards.
• Ability to interpret complex clinical and scientific datasets and identify medically relevant patterns or concerns.
• Familiarity with clinical data review tools, EDC systems, listings, dashboards, and data visualization outputs.
• Strong attention to detail, with the ability to distinguish clinically meaningful findings from data noise.
• Ability to work effectively in cross-functional teams and communicate findings clearly to both scientific and operational colleagues.
• Analytical mindset with the ability to use facts and data to guide decisions.
• Accountability and Reliability: Take ownership for performance, be dependable, and support others to achieve collective goals.
• Align on common objectives and use facts and data to reach fair, effective decisions.
• Contribute to balanced roles within the team, support delegation, and help colleagues reach their full potential.