At a Glance
- Tasks: Lead innovative bioprocessing projects and drive automation in cutting-edge therapies.
- Company: Join a pioneering organisation at the forefront of cell and gene therapy.
- Benefits: Competitive salary, flexible working, and opportunities for professional growth.
- Other info: Collaborative environment with excellent career advancement opportunities.
- Why this job: Make a real impact in the biotech field and shape the future of healthcare.
- Qualifications: PhD or BSc in life sciences with relevant industry experience required.
The predicted salary is between 40500 - 49500 £ per year.
The Senior Bioprocessing Scientist will apply in-depth technical expertise across a range of projects to support the development of bioprocesses by adapting manual 2D processes into closed and automated processes, using technologies including stirred-tank bioreactors and other closed processing systems, linking unit operations, and integrating state of the art automation and digitalisation technologies to reduce cost of manufacturing and strengthen supply for manufacture of ATMPs. The role will be high profile, both within the organisation and outward facing to the Company’s stakeholders and Collaborators. As an active member of the CGT Catapult Scale Enabling Technology (SET) Edinburgh team, the Senior Bioprocessing Scientist will work closely with the London and Stevenage SET teams as well as the CGT Catapult Manufacturing Innovation Centres (MICs) in Stevenage and Braintree to plan and deliver on commercial, collaborative and in-house process development projects to drive the Up-Stream Process (USP) development work, automation and control within the CGT Catapult portfolio.
Key Responsibilities
- Provide subject matter expertise in bioprocessing of ATMPs including autologous and allogeneic products.
- Engage and collaborate with CGT Catapult teams across different sites and disciplines.
- Use in-depth knowledge of ATMP process development, upstream bioprocessing, PAT and data analysis techniques to enable the delivery of process development and automation projects.
- Drive towards integration of automation and digitalisation for cost of goods reduction by working with data, analytical, and IT teams.
- Provide subject matter expertise in the planning and execution of laboratory work, the review of ATMP related products and processes, and the preparation of technical reports.
- Provide leadership/ownership of laboratory activities associated with assigned USP development projects, including stock control, experimental design/planning/reporting, compliance with onsite procedures.
- Support, engage and communicate effectively with internal and external stakeholders to disseminate newly established innovative capabilities to the wider UK industry.
- Agree resource requirements and budgets with project sponsors, project managers and Lead Scientists.
- Produce, review experimental plans, witness completed experiments in the ELN, ensure raw data is processed according to data integrity guidelines and stored according to company policies, producing and reviewing study reports.
- Present data at conferences and meetings where appropriate.
- Provide line management and leadership to junior team members and mentoring of scientists within the team.
- Work with technology providers and organisations to ensure that the CGT Catapult is a leader in scalable, automated process development for ATMPs.
- Support Lead Scientist in day to day operational management of the facility.
- Drive continuous improvement initiatives to optimise operational, laboratory and administrative processes whilst enhancing efficiency.
- Contribution to out of hours work as required, demonstrating flexibility to meet project and business needs.
Skills, Knowledge and Expertise
- Relevant experience gained within a commercial biotechnology, biopharmaceutical, advanced therapies, or life sciences environment is essential.
- Experience in analytical assays such as flow cytometry, qPCR, metabolite profiling and cell counting is essential.
- Demonstrable experience of executing agreed research independently with minimal supervision is essential.
- Experience of bioprocessing data structuring, analysis and formatting is essential.
- Experience in bioprocessing and scaling, including upstream processing using stir tank bioreactor and other cell culture technologies and techniques are essential, including DASbox, BioBLU, ambr250, Quantum Flex, univessel bioreactor systems, 2D/3D culture systems, cell handling (e.g. T-cells, NK-cells, HEK cells), cell thawing, expansion, differentiation and banking.
- Proven experience in PSC cell bioprocessing, including the culture, expansion and optimisation of cells using 2D and 3D systems.
- Proven experience of effectively delivering training and developing other team members.
- Experience in conducting technical Genetically Modified Organisms risk assessments to ensure biosafety compliance.
- Experience of designing end to end bioprocess workflows with a focus on automation and digitalisation to drive standardisation and process closure.
- Experience in Health and Safety management, including generation of risk assessments and ensuring COSHH compliance, contribution to incidents and near miss investigations, safety inspections and audits, equipment safety with an interest in advancing knowledge through NEBOSH certification.
- Experience of statistical tools such as method validation and/or Design of Experiments to drive efficient and robust experimental design is desirable.
- Experience of process scale-up and technology transfer to/from commercial and research organisations is desirable.
- Experience of integrating PAT technologies into bioprocessing development workflows is desirable.
Education/Qualifications
- PhD or BSc in a relevant subject, supported by relevant industrial experience in the life sciences or bio-engineering field.
Senior Bioprocessing Scientist in Edinburgh employer: Cell and Gene Therapy Catapult
At Cell and Gene Therapy Catapult, we pride ourselves on being an excellent employer that fosters a collaborative and innovative work culture in the heart of Fisher's Pond, England. Our commitment to employee growth is evident through continuous training opportunities and a supportive environment that encourages professional development, making it an ideal place for those passionate about advancing cutting-edge therapies.
Contact Details:
Cell and Gene Therapy Catapult Recruitment Team
StudySmarter Expert Advice🤫
We think this is how you could land Senior Bioprocessing Scientist in Edinburgh
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We think you need these skills to ace Senior Bioprocessing Scientist in Edinburgh
Some tips for your application 🫡
Show Off Your Lab Skills:In the biotechnology field, it's super important to highlight your lab experience in your CV. Be sure to mention specific techniques or instruments you've mastered (think PCR, gel electrophoresis, etc.) and any relevant projects you've worked on. This will show Cell and Gene Therapy Catapult that you have the hands-on skills they need.
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How to prepare for a job interview at Cell and Gene Therapy Catapult
✨Brush Up on Lab Techniques
Since you're eyeing a full-time gig in biotechnology, make sure you're well-versed in the lab techniques relevant to the role. Be ready to talk about PCR, CRISPR, or any specific methods mentioned in the job description at Cell and Gene Therapy Catapult. You might even be asked to demonstrate your understanding of these processes.
✨Know Your Bioinformatics Tools
Get comfortable with bioinformatics tools that are commonly used in the industry, like BLAST or Bioconductor. These are key in biotechnology, and having hands-on experience or at least familiarity can set you apart. Prepare to discuss any relevant projects you've worked on, especially if they involved data analysis or genomic research.
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✨Research Recent Biotech Innovations
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