Director of Application Engineering

Director of Application Engineering

Full-Time 81000 - 99000 £ / year (est.) On-site
Causaly Inc.

At a Glance

  • Tasks: Lead engineering teams to develop AI-powered biomedical applications that drive real customer value.
  • Company: Causaly is revolutionising biomedicine with cutting-edge AI technology.
  • Benefits: Competitive salary, inclusive culture, and opportunities for professional growth.
  • Other info: Join a mission-driven team focused on accelerating scientific breakthroughs for all humankind.
  • Why this job: Make a significant impact in the biomedical field while leading innovative engineering teams.
  • Qualifications: 10+ years in software engineering and 4+ years in leadership roles, preferably in scale-up environments.

The predicted salary is between 81000 - 99000 £ per year.

About us: Causaly is redefining how humans acquire knowledge and develop insights in biomedicine. Our AI-powered platform enables researchers and decision-makers to discover and interpret evidence from millions of scientific publications, clinical trials, regulatory documents, and other complex data sources in minutes. We are building the world’s most advanced biomedical knowledge platform, powered by a high-precision Knowledge Graph and GenAI capabilities. Our technology is already used by leading biopharmaceutical organizations to accelerate drug discovery, improve safety, and drive better decision-making. Backed by top-tier investors including ICONIQ, Index Ventures, Pentech, and Marathon, we are scaling rapidly and expanding our product suite and market presence.

Leading the engineering organisation responsible for our agentic research product and customer-facing applications. You’ll set direction, strengthen the management layer and ensure teams deliver reliable products that create measurable customer value.

What you'll own

  • Direction and structure: set the direction for application engineering within our engineering strategy; define team structure and the operating model; make the significant resourcing and structural decisions.
  • Delivery: monthly plans that teams actually meet, built with Product on real capacity, with trade-offs made explicit when priorities change and progress visible to everyone; drive roadmaps and cross-functional technical programmes.
  • Customer value: keep your teams focused on outcomes, not output. Understand the problems our customers' scientists are solving, check that what we ship gets used and makes a difference, and change or stop what doesn't.
  • Quality and reliability: own the quality, security and operational health of what your teams ship, from release practice to incident response.
  • People and culture: manage and coach engineering managers, build a strong management layer, own the hiring plan, and be accountable for the culture across your org.
  • AI-first engineering: drive AI-first workflows across all your teams, invest in reusable tooling and enablement, and set standards and ROI targets for how we build with agents, from planning to code review to release.
  • Partnership: work with VPs and Product leadership on what we build, and with Data, DevOps and Security on how it fits together; represent engineering externally in hiring.

Your impact is department-wide: you'll be part of the engineering leadership team, help shape engineering-wide decisions, and step in to lead engineering when needed.

What success looks like

  • Teams plan on real capacity with Product and deliver predictably, in small increments.
  • Every area has a clear owner, and teams are shaped around clear mandates.
  • AI-first engineering is how the whole function works: from planning to automated testing, review and release.
  • Your engineering managers grow, and the teams become a place strong engineers want to join and stay.
  • Teams judge success by the value customers get, not the number of features shipped, and customers notice the difference release after release.

What we’re looking for

  • 10+ years in software engineering and 4+ years leading engineering managers, ideally in a scale-up environment.
  • A track record of predictable delivery: planning on real capacity, limiting work in progress, and saying no or making trade-offs with Product.
  • A customer-first mindset: you measure your teams by the value they deliver, not the features they ship, and you bring engineers close to the customers they build for.
  • Real experience leading teams that build with AI coding agents (Claude Code or similar), including how review, testing and quality change when agents write most of the code.
  • Experience leading distributed teams across countries and time zones.
  • Clear, direct communication with engineers, product leaders and executives.

How we’ll assess you

  • Leadership: broad engineering leadership across several sub‑domains; a strategic thinker who can judge direction for areas you don't personally know in depth.
  • AI fluency: you already embed AI in how your teams work, and you can take it to the next level for a whole function: AI‑first workflows across teams.

Nice to have

  • Experience leading teams that ship LLM, ML or other AI‑powered features to production, with enough technical depth to challenge architecture and quality decisions.
  • Life sciences, biomedical data or B2B SaaS for enterprise customers.
  • Hands‑on experience building agentic systems (multi‑step agents, tool use, evaluation).

We are on a mission to accelerate scientific breakthroughs for ALL humankind, and we are proud to be an equal opportunity employer. We welcome applications from all backgrounds and fairly consider qualified candidates without regard to race, ethnic or national origin, gender, gender identity or expression, sexual orientation, disability, neurodiversity, genetics, age, religion or belief, marital/civil partnership status, domestic / family status, veteran status or any other difference.

Director of Application Engineering employer: Causaly Inc.

Causaly is an exceptional employer, offering a dynamic work culture that fosters innovation and collaboration in the rapidly evolving field of biomedicine. With competitive compensation, comprehensive benefits including private medical insurance and personal development budgets, employees are empowered to grow their careers while making a meaningful impact on scientific breakthroughs. Located in New York, team members enjoy the vibrant city life alongside the opportunity to work with cutting-edge AI technology that is transforming the industry.

Causaly Inc.

Contact Details:

Causaly Inc. Recruitment Team

StudySmarter Expert Advice🤫

We think this is how you could land Director of Application Engineering

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We think you need these skills to ace Director of Application Engineering

Leadership in Software Engineering
Team Management
Predictable Delivery
Customer-Focused Mindset
AI Coding Agents Experience
Distributed Team Leadership
Clear Communication

Some tips for your application 🫡

Show off your coding skills:When applying for a software engineering role, it's super important to showcase your coding skills. Make sure your CV includes your tech stack, any relevant programming languages you’re comfortable with, and examples of projects you've worked on. If you have a GitHub profile, link it up! We love to see code in action.

Tailor your portfolio:For a full-time role, we’d expect to see some solid examples of your work in your portfolio. Make sure to include at least two or three projects that highlight your problem-solving skills and your ability to work with different technologies. Focus on the projects that are most relevant to the position at Causaly Inc..

Craft a killer cover letter:Your cover letter is your chance to stand out—make it personal! Explain why you want to work at Causaly Inc. and how your skills align with the role. Show us your passion for software development. We dig enthusiastic candidates who understand the value of collaboration and continuous learning!

Be clear and concise:When it comes to writing your CV and cover letter, clarity is key. Avoid jargon that could confuse us and stick to simple, direct language. Highlight your achievements with quantifiable results where possible, and keep everything easy to read. A well-organised application goes a long way!

How to prepare for a job interview at Causaly Inc.

✨Brush Up on Your Coding Skills

For a full-time software engineering role, it's crucial that we stay sharp with our coding abilities. Expect technical questions that might involve solving problems on the spot or discussing algorithms. Practise on platforms like LeetCode or HackerRank to get comfortable with the types of questions that often come up.

✨Know Your Tools and Frameworks

Make sure we’re well-acquainted with the tools and technologies listed in the job description. Familiarise ourselves with any specific frameworks or programming languages mentioned. If Causaly Inc. uses React or Node.js, for instance, be ready to discuss how we’ve used them in previous projects or coursework.

✨Showcase Your Projects

Bring along a portfolio that highlights our best work. This could be code samples, GitHub repositories, or any side projects we’ve built. Make sure we can talk through our thought process for each project, especially the challenges we faced and how we solved them—this shows our problem-solving skills in action.

✨Prepare for Behavioural Questions

While technical skills are key, full-time positions also require cultural fit. Be ready to discuss our previous experiences and how we handle teamwork, conflict, and deadlines. Brush up on the STAR method—Situation, Task, Action, Result—to clearly articulate our past experiences when discussing how we've contributed to a team.