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- Tasks: Join our team to design and optimise drug candidates for postpartum depression.
- Company: Be part of Cardiff University's Medicines Discovery Institute, leading in innovative therapeutic research.
- Benefits: Enjoy a competitive salary, flexible working options, and a vibrant, inclusive community.
- Why this job: Make a real impact in neuroscience and mental health while collaborating with top researchers.
- Qualifications: Seeking skilled Medicinal Chemists with a passion for drug discovery and innovation.
- Other info: Full-time role starting April 2025, with opportunities for professional growth.
The predicted salary is between 34000 - 45000 Β£ per year.
Research Associate
19870BR
Cardiff School of Biosciences
Research
Advert
Research Associate (2 Posts)
The Medicines Discovery Institute (MDI) represents a major investment in translational science by Cardiff University. The goal of the Institute is to translate world-leading research on scientific understanding of disease mechanisms into innovative therapeutic approaches. Our vision is to play a leading role in discovering new medicines in areas of high unmet need, with a particular emphasis on neuroscience, mental health, and cancer. We have created a vibrant community of researchers across both academic and biotech sectors engaged in major research programmes which build off the unique strengths of Cardiff University and work collaboratively with other universities and companies across Wales and internationally.
The Medicines Discovery Institute is looking to recruit Research Associates to support the medicinal chemistry activities of a MRC funded project to develop selective allosteric modulators of extrasynaptic Ξ΄-GABAA receptors for the treatment of postpartum depression (PPD). In particular, we are seeking highly skilled and motivated Medicinal Chemists to join our Late Lead Optimization team. The successful candidates will work alongside the project team and contribute to the design, optimisation and synthesis of lead compounds to develop potential drug candidates.
This will include the design and synthesis of novel compounds to improve potency, selectivity, and pharmacokinetic properties; conducting structure-activity relationship (SAR) studies to identify key molecular features; utilise computational chemistry tools to guide compound design; analyze and interpret biological data to inform chemical modifications; preparing and presenting research findings to internal stakeholders.
The posts will be based at Cardiff University and will be part of a multi-disciplinary drug discovery team. For informal inquiries, please contact medicinesdiscovery@cardiff.ac.uk.
These positions are full-time (35 hours per week), starting 1 April 2025 and fixed term until 31 March 2026.
Salary: Β£40,497 β Β£45,413 per annum (Grade 6). Appointments to roles at Cardiff University are usually made at bottom of scale unless in exceptional circumstances.
Date advert posted: Thursday, 17 April 2025
Closing date: Thursday, 8 May 2025
Applications may be submitted in Welsh, and an application submitted in Welsh will not be treated less favourably than an application submitted in English.
Cardiff University is committed to supporting and promoting equality and diversity and to creating an inclusive working environment. We believe this can be achieved through attracting, developing, and retaining a diverse range of staff from many different backgrounds. We therefore welcome applicants from all sections of the community regardless of sex, ethnicity, disability, sexual orientation, trans identity, relationship status, religion or belief, caring responsibilities, or age. In supporting our employees to achieve a balance between their work and their personal lives, we will also consider proposals for flexible working or job share arrangements.
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Research Associate employer: Cardiff University / Prifysgol Caerdydd
Contact Detail:
Cardiff University / Prifysgol Caerdydd Recruiting Team
StudySmarter Expert Advice π€«
We think this is how you could land Research Associate
β¨Tip Number 1
Network with professionals in the field of medicinal chemistry and drug discovery. Attend relevant conferences, workshops, or seminars where you can meet researchers from the Medicines Discovery Institute and other institutions. Building these connections can provide valuable insights and potentially lead to referrals.
β¨Tip Number 2
Familiarise yourself with the latest research and developments in allosteric modulators and their applications in treating postpartum depression. Being well-versed in current literature will not only enhance your understanding but also demonstrate your genuine interest and expertise during any discussions.
β¨Tip Number 3
Prepare to discuss your previous research experiences and how they relate to the specific requirements of the role. Highlight any relevant projects where you designed or synthesised compounds, as well as your experience with structure-activity relationship studies and computational chemistry tools.
β¨Tip Number 4
Practice your presentation skills, as you will need to prepare and present research findings to internal stakeholders. Being able to communicate complex scientific concepts clearly and effectively will be crucial in this role, so consider doing mock presentations to friends or colleagues for feedback.
We think you need these skills to ace Research Associate
Some tips for your application π«‘
Understand the Role: Read the job description thoroughly to understand the specific skills and experiences required for the Research Associate position. Highlight your relevant experience in medicinal chemistry and any related projects you've worked on.
Tailor Your CV: Customise your CV to reflect the qualifications and experiences that align with the role. Emphasise your expertise in drug discovery, compound design, and any computational chemistry tools you have used.
Craft a Compelling Cover Letter: Write a cover letter that not only outlines your qualifications but also demonstrates your passion for neuroscience and mental health research. Mention specific projects or achievements that relate to the goals of the Medicines Discovery Institute.
Proofread and Edit: Before submitting your application, carefully proofread all documents for spelling and grammatical errors. Ensure that your application is clear, concise, and professionally presented to make a strong impression.
How to prepare for a job interview at Cardiff University / Prifysgol Caerdydd
β¨Understand the Research Focus
Familiarise yourself with the specific research areas of the Medicines Discovery Institute, particularly in neuroscience and mental health. Be prepared to discuss how your background and skills align with their goals, especially regarding postpartum depression and drug discovery.
β¨Showcase Your Technical Skills
Highlight your experience in medicinal chemistry, particularly in lead optimisation and structure-activity relationship (SAR) studies. Be ready to provide examples of past projects where you designed or synthesised compounds, and discuss any computational chemistry tools you have used.
β¨Prepare for Collaborative Discussion
Since the role involves working within a multi-disciplinary team, be prepared to discuss your teamwork experiences. Share examples of how you've collaborated with others in research settings, and demonstrate your ability to communicate complex scientific concepts clearly.
β¨Present Your Research Findings
As part of the role, you'll need to present findings to stakeholders. Practice summarising your research in a concise manner, focusing on key results and implications. This will show your ability to communicate effectively and engage with various audiences.