At a Glance
- Tasks: Join our drug discovery team to innovate in medicinal chemistry and develop high-quality compounds.
- Company: CardiaTec is a cutting-edge biosciences company focused on cardiovascular disease research.
- Benefits: Enjoy hybrid working options, competitive salary, share options, and a flexible work environment.
- Why this job: Make a real-world impact in drug discovery while collaborating with top experts in a dynamic team.
- Qualifications: PhD in Medicinal Chemistry with 3+ years of drug discovery experience; expertise in organic chemistry required.
- Other info: We value diversity and encourage applicants who may not meet every requirement to apply.
The predicted salary is between 43200 - 72000 £ per year.
Medicinal Chemist, Drug Discovery – Senior/Associate Principal Scientist
CardiaTec Biosciences LTD
9 Hills Road, Cambridge, UK, CB2 1GE
About the Job
We are looking for a senior medicinal chemist to join our drug discovery team to drive innovation by applying organic and medicinal chemistry expertise to our drug discovery and development projects.
Location : Cambridge, London, or Oxford – Hybrid working. Fully remote options are also available limited to the UK and Europe.
Contract : Full-time
Compensation : Competitive Salary and Share Options Package
Start Date: As soon as possible
Responsibilities:
- Apply expertise in organic and medicinal chemistry to design and develop high-quality compounds with favourable drug-like properties, aligned with CardiaTec’s platform target predictions.
- Provide strategic direction and technical oversight to CROs and external collaborators, ensuring timely delivery of high-quality data and outputs.
- Collaborate with multidisciplinary teams, including biology and technology experts, to drive innovative drug discovery and infrastructure development.
- Implement and manage frameworks to identify and prioritise the most promising small molecules and starting points for drug discovery projects.
- Maintain detailed experimental records using Benchling and contribute to publications, grant applications, and scientific presentations to support the company’s research goals.
Key Requirements:
- PhD in Medicinal Chemistry or a related discipline, with over 3 years of experience in drug discovery within the pharmaceutical, biotech, or CRO industry, focusing on small molecules.
- Proven expertise in organic and medicinal chemistry, including structure-based and ligand-based drug discovery, and familiarity with computational approaches.
- Track record of leading or co-leading drug discovery programmes from hit identification to lead optimisation, ideally to candidate delivery.
- Experience managing and collaborating with external chemistry partners and CROs.
- Demonstrable skills in the design, synthesis, and characterisation of small molecules, with familiarity in computational chemistry tools.
If you feel that you do not meet every single requirement of this role, we still want to hear from you! We encourage you to apply and have a discussion with us about the role or others that we may have either now or in the future.
Working at CardiaTec:
Join our dynamic team to contribute to groundbreaking innovations with real-world impact. We embrace diversity and inclusion, fostering lasting professional and personal connections. Our flexible work environment combines remote and office work, with scheduled in-person weeks for team collaboration, brainstorming sessions, and fun team-building activities.
If you are enthusiastic about making a difference in the world of drug discovery and enjoy tackling complex challenges, CardiaTec is the perfect place for you!
Company Description:
CardiaTec’s highly multidisciplinary team works to leverage computational methods to decode the biology behind cardiovascular disease. Here, we analyse large and high-dimensional human multi-omics data from heart tissues to better navigate complex disease biology and identify novel and differentiated therapeutics.
The company spun out of the Han Lab at the University of Cambridge and has brought together some of the best minds in the field, represented across leading organisations including Bristol Myers Squibb, Cleveland Clinic, and Recursion Pharmaceuticals.
Seniority level
Mid-Senior level
Employment type
Full-time
Job function
Research, Analyst, and Information Technology
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Medicinal Chemist, Drug Discovery - Senior/Associate Principal Scientist employer: CardiaTec Bio
Contact Detail:
CardiaTec Bio Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Medicinal Chemist, Drug Discovery - Senior/Associate Principal Scientist
✨Tip Number 1
Make sure to highlight your experience in drug discovery, especially if you've led projects from hit identification to lead optimization. This is crucial for a role that requires strategic direction and technical oversight.
✨Tip Number 2
Familiarize yourself with the latest computational chemistry tools and methodologies. Since the role emphasizes collaboration with multidisciplinary teams, showcasing your knowledge in this area can set you apart.
✨Tip Number 3
Network with professionals in the field through platforms like LinkedIn. Engaging with CardiaTec’s content or employees can give you insights into their culture and values, which is beneficial during interviews.
✨Tip Number 4
Prepare to discuss your collaborative experiences with CROs and external partners. Being able to demonstrate your ability to manage these relationships effectively will be key in this role.
We think you need these skills to ace Medicinal Chemist, Drug Discovery - Senior/Associate Principal Scientist
Some tips for your application 🫡
Understand the Role: Make sure to thoroughly read the job description for the Medicinal Chemist position. Highlight the key responsibilities and requirements, and think about how your experience aligns with them.
Tailor Your CV: Customize your CV to emphasize your relevant experience in medicinal chemistry and drug discovery. Include specific examples of projects you've worked on that demonstrate your expertise in organic and medicinal chemistry.
Craft a Compelling Cover Letter: Write a cover letter that showcases your passion for drug discovery and your fit for the role. Mention your PhD and any significant achievements in drug discovery, as well as your ability to collaborate with multidisciplinary teams.
Highlight Collaborative Experience: Since collaboration is key in this role, be sure to mention any experience you have working with external partners or CROs. Provide examples of how you contributed to successful outcomes in these collaborations.
How to prepare for a job interview at CardiaTec Bio
✨Showcase Your Expertise
Be prepared to discuss your experience in organic and medicinal chemistry in detail. Highlight specific projects where you applied your skills in drug discovery, especially those that involved small molecules. This will demonstrate your capability to contribute effectively to CardiaTec's innovative drug discovery efforts.
✨Collaborative Mindset
Since the role involves working with multidisciplinary teams, emphasize your experience in collaboration. Share examples of how you've successfully worked with biologists, technology experts, or external partners to drive projects forward. This will show that you can thrive in a team-oriented environment.
✨Familiarity with Tools
Make sure to mention your experience with computational chemistry tools and platforms like Benchling. Discuss how you've used these tools in past projects to design, synthesize, and characterize compounds. This knowledge is crucial for maintaining detailed experimental records and contributing to scientific publications.
✨Passion for Innovation
Express your enthusiasm for drug discovery and your desire to tackle complex challenges. Share any personal motivations or experiences that drive your passion for making a difference in the field. This will resonate well with CardiaTec's mission and culture of innovation.